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Sinovac COVID vaccine shows modest efficacy against SARS-CoV-2 infection in children 3 to 5 years

Researchers investigate the efficacy of CoronaVac, COVID-19 vaccine developed by Sinovac Biotech, in children aged three to five years.

20 Mar 2022

Trial shows safety and immunogenicity of immunotherapy with chemoradiation in cervical cancer patients

A Phase I/Ib trial conducted by the National Cancer Institute (NCI) National Clinical Trials Network (NCTN) group NRG Oncology, NRG-GY017, concluded that the addition of the immunotherapy drug atezolizumab prior to and concurrently given with chemoradiation (CRT) treatment was safe for women with node-positive, locally advanced cervical cancer.

19 Mar 2022

HRR mutational status associated with survival outcomes in recurrent platinum-sensitive ovarian cancer

Results of a biomarker analysis of the NRG Oncology NRG-GY004 trial were presented at a Seminal Session during the Society for Gynecologic Oncology's (SGO) Annual Meeting on Women's Cancer in March 2022.

19 Mar 2022

Combination therapy shows promising results in patients with recurrent ER-positive endometrial cancer

A combination therapy that targets cancer cells from within and without caused tumors to shrink or stabilize in 75% of patients with recurrent or persistent estrogen receptor- (ER-) positive endometrial cancer, results from a recent clinical trial show.

19 Mar 2022

Higher doses of antibiotics are needed to eliminate infection in a polymicrobial environment

A study has found that much higher doses of antibiotics are needed to eliminate a bacterial infection of the airways when other microbes are present.

19 Mar 2022

Covalent protein nanobodies for neutralizing SARS-CoV-2 and its variants

Researchers developed covalent nanobodies to neutralize severe acute respiratory syndrome coronavirus-2 and its variants.

18 Mar 2022

Study evaluates COVID-19 vaccination with recombinant accessory protein-deficient SARS-CoV-2

Researchers assessed the impact of recombinant accessory protein-deficient severe acute respiratory syndrome coronavirus 2 immunization against SARS-CoV-2 transmission and disease severity.

18 Mar 2022

Study shows BCG vaccination reduces SARS-CoV-2-induced lung inflammation in hamsters

Researchers tested the effectiveness of the BCG vaccine in SARS-CoV-2-infected Syrian hamsters.

18 Mar 2022

New approach radically increases the success of breast cancer immunotherapy

A study published in the journal Nature Cancer, carried out within the Cancer Programme at the Hospital del Mar Medical Research Institute (IMIM-Hospital del Mar) by the Cancer Stem Cells and Metastasis Dynamics Laboratory, led by Dr. Toni Celià-Terrassa, and the Laboratory of Molecular Cancer Therapy, coordinated by Dr. Joan Albanell, with the participation of international centers, has discovered an approach that radically increases the success of immunotherapy in one of the most aggressive types of tumors, triple-negative breast cancer.

17 Mar 2022

Impact of new COVID vaccinations as novel variants emerge

Researchers explores the changing value of COVID-19 vaccines in a scenario of dynamic immunity and rapidly evolving variants of concern.

17 Mar 2022

Single dose of Pfizer vaccine reduces risk of SARS-CoV-2 infection in kids

Researchers discuss the efficacy of COVID-19 vaccines in young people and children when the SARS-CoV-2 Delta- and Omicron-dominant periods.

17 Mar 2022

BNT162b2 booster vaccination induces robust humoral and cellular immune responses

Scientists evaluate the humoral and cellular immune responses in individuals who have received a third booster dose of mRNA-based COVID-19 vaccine.

17 Mar 2022

Evaluating vesicular stomatitis virus-based COVID-19 vaccines against SARS-CoV-2 variants in hamsters

Researchers assessed the efficacy of vesicular stomatitis virus-based coronavirus disease 2019 vaccines in Syrian golden hamsters.

17 Mar 2022

MHRA authorizes new medicine for COVID-19 prevention

A new medicine, Evusheld (tixagevimab/cilgavimab), has today been authorised for COVID-19 prevention by the Medicines and Healthcare products Regulatory Agency (MHRA) after meeting the UK regulatory standards of safety, quality and effectiveness.

17 Mar 2022

The immunogenicity of homologous and heterologous boosters in adults who received inactivated COVID-19 vaccine six months prior

Researchers compared the efficacy of booster doses of heterologous intramuscular and aerosolized adenovirus-vectored vaccine, a recombinant protein-based ZF2001 vaccine, and homologous CoronaVac vaccines.

17 Mar 2022

The safety and immunogenicity of NVSI-06-08 as a heterologous booster dose in adults previously vaccinated with BBIBP-CorV

Researchers assessed the safety profile and immunogenicity of a heterologous NVSI-06-08 boost against SARS-CoV-2 variants in individuals doubly vaccinated with the inactivated vaccine BBIBP-CorV.

17 Mar 2022

Efficacy News and Research

Sinovac COVID vaccine shows modest efficacy against SARS-CoV-2 infection in children 3 to 5 years

Trial shows safety and immunogenicity of immunotherapy with chemoradiation in cervical cancer patients

HRR mutational status associated with survival outcomes in recurrent platinum-sensitive ovarian cancer

Combination therapy shows promising results in patients with recurrent ER-positive endometrial cancer

Higher doses of antibiotics are needed to eliminate infection in a polymicrobial environment

Covalent protein nanobodies for neutralizing SARS-CoV-2 and its variants

Study evaluates COVID-19 vaccination with recombinant accessory protein-deficient SARS-CoV-2

Study shows BCG vaccination reduces SARS-CoV-2-induced lung inflammation in hamsters

New approach radically increases the success of breast cancer immunotherapy

Impact of new COVID vaccinations as novel variants emerge

Single dose of Pfizer vaccine reduces risk of SARS-CoV-2 infection in kids

BNT162b2 booster vaccination induces robust humoral and cellular immune responses

Evaluating vesicular stomatitis virus-based COVID-19 vaccines against SARS-CoV-2 variants in hamsters

MHRA authorizes new medicine for COVID-19 prevention

The immunogenicity of homologous and heterologous boosters in adults who received inactivated COVID-19 vaccine six months prior

The safety and immunogenicity of NVSI-06-08 as a heterologous booster dose in adults previously vaccinated with BBIBP-CorV

Frail and older males more vulnerable to COVID-19 than females

The effects of anti-SARS-CoV-2 monoclonal antibodies on pregnant and postpartum women

Inhalable ‘aerogel’ induces immune response against COVID-19 in the lungs of mice

SLU physician-scientist receives NIH funding for Short Bowel Syndrome research

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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