Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Wistar scientists describe mechanics of oncogene-induced senescence

Researchers from The Wistar Institute explain a new molecular mechanism behind the phenomenon of oncogene-induced senescence. By depriving the cell of the ability to make new nucleotides-the building blocks of DNA molecules-cells can suppress cancer development by forcing a damaged cell into a senescent state, where the cell remains alive yet cannot reproduce.

5 Apr 2013

Three institutions partner to create research breakthroughs in children's health

Virginia Tech, Children's National Medical Center, and the George Washington University have partnered in a unique program to create research breakthroughs in children's health.

4 Apr 2013

Reformulated version of anti-HIV gel safe for HIV-negative men and women

A reformulated version of an anti-HIV gel developed for vaginal use was found safe and acceptable by HIV-negative men and women who used it rectally, according to a Phase I clinical trial published today in PLOS ONE.

4 Apr 2013

Study shows cholesterol rafts can shepherd genetic payloads into cancer cells

DNA, siRNA and miRNA can reprogram cancer cells - that is, if these nucleic acids could cross through the cell membrane. A University of Colorado Cancer Center study published today in the journal Therapeutic Delivery shows that cholesterol "rafts" can shepherd genetic payloads into cancer cells.

3 Apr 2013

Researchers develop new guidelines to treat recently diagnosed multiple myeloma patients

Researchers at Mayo Clinic Cancer Center have developed new guidelines to treat recently diagnosed multiple myeloma patients who are not participating in clinical trials. The guidelines give physicians practical, easy to follow recommendations for providing initial therapy, stem cell transplant and maintenance therapy.

2 Apr 2013

New born neurons as a therapeutic strategy: an interview with Mi-Hyeon Jang, Mayo Clinic in Rochester, Minnesota

There are two regions in the brain that continue to produce new neurons well into adulthood. One of these regions is the hippocampus and as we converse this region is actively involved in memory formation, mood regulation and cognition.

2 Apr 2013

Inovio Pharmaceuticals reports release of phase II clinical trial results of ChronVac-C

Inovio Pharmaceuticals, Inc. today announced the release of preliminary clinical trial results by its collaborator ChronTech AS of their open label phase II clinical study of ChronVac-C, ChronTech's vaccine to treat hepatitis C virus infection.

2 Apr 2013

New research discovery in mosquitoes could lead to possible tools for controlling malaria

A surprising research discovery in mosquitoes could affect future prospects for malaria control. A team of scientists from West Africa, the United States and the United Kingdom found that the mosquito, Anopheles gambiae, which was thought to be splitting into two completely new species, may actually have a more complex range of forms due to frequent inter-mating.

2 Apr 2013

New research shows how metabolism and physiology are connected to diet

Sometimes you just can't resist a tiny piece of chocolate cake. Even the most health-conscious eaters find themselves indulging in junk foods from time to time. New research by scientists at the University of Massachusetts Medical School raises the striking possibility that even small amounts of these occasional indulgences may produce significant changes in gene expression that could negatively impact physiology and health.

30 Mar 2013

Researchers identify HNF1B gene that can increase risk of ovarian cancer

Researchers at Mayo Clinic Cancer Center have identified a novel gene that can contribute to a woman's susceptibility for developing ovarian cancer. Researchers identified the gene, called HNF1B, through large-scale analysis of more than 16,000 women with ovarian cancer and more than 26,000 healthy women.

28 Mar 2013

Inflammation and epigenetics: an interview with Dr Belkina and Dr Denis, Boston University School of Medicine

Inflammation can be thought of as taking two major forms: acute or chronic. Acute inflammation, which can be painful, usually arises quickly and resolves quickly. It accompanies bacterial infections, traumatic injury and is useful to fight infections and promote healing.

28 Mar 2013

Researchers shed new light on role of methylation in gene expression

Researchers at UC Davis and the University of British Columbia have shed new light on methylation, a critical process that helps control how genes are expressed.

28 Mar 2013

Academic medical centers launch ASD sub-registry within ResearchMatch

Each year, only five percent of the estimated 1.5 million children with an autism spectrum disorder in the US participate in clinical research studies. This is in stark contrast to pediatric cancer studies, which have a nearly 90 percent enrollment rate - a rate that has helped advance treatment and outcomes for childhood cancers substantially in the last decade.

27 Mar 2013

UCI study finds novel molecular mechanism that helps trigger formation of long-term memory

UC Irvine neurobiologists have found a novel molecular mechanism that helps trigger the formation of long-term memory. The researchers believe the discovery of this mechanism adds another piece to the puzzle in the ongoing effort to uncover the mysteries of memory and, potentially, certain intellectual disabilities.

26 Mar 2013

LMU researchers identify microRNA that offers promising target for new therapies

Atherosclerosis, an inflammatory reaction, is at the root of the most common forms of cardiovascular disease. Researchers at Ludwig-Maximilians-Universitaet in Munich have now identified a microRNA that plays a prominent role in the process, and offers a promising target for new therapies.

25 Mar 2013

Epizyme receives patent for drug candidate for genetically defined type of non-Hodgkin lymphomas

Epizyme, Inc., a clinical stage biopharmaceutical company creating innovative personalized therapeutics for patients with genetically defined cancers, announced today that it has received a Notice of Issuance from the U.S. Patent and Trademark Office for its patent application entitled "ARYL-OR HETEROARYL-SUBSTITUTED BENZENE COMPOUNDS", U.S. Patent No.: 8,410,088.

24 Mar 2013

Two genes associated with rare autism-related disorders linked to general forms of autism: Study

A new study finds that two genes individually associated with rare autism-related disorders are also jointly linked to more general forms of autism. The finding suggests a new genetic pathway to investigate in general autism research.

22 Mar 2013

Gene LY86 identified as likely contributor to obesity

Food and environment can chemically alter your gene function and scientists have identified a gene that is consistently altered in obesity.

22 Mar 2013

Cocaine can be lethal for people living with HIV

Cocaine, already a damaging drug for those with healthy immune systems, can be lethal for those living with human immunodeficiency virus. Mudit Tyagi, Ph.D., assistant professor of medicine at the George Washington University School of Medicine and Health Sciences, has received two federally funded grants to study how dangerous this combination is in HIV patients.

22 Mar 2013

Study provides new insights about polycystic ovarian syndrome, insulin resistance

A group of tiny RNA molecules with a big role in regulating gene expression also appear to have a role in causing insulin resistance in woman with polycystic ovary syndrome and, perhaps, in all women, researchers report.

20 Mar 2013

Gene Expression News and Research

Further Reading

Wistar scientists describe mechanics of oncogene-induced senescence

Three institutions partner to create research breakthroughs in children's health

Reformulated version of anti-HIV gel safe for HIV-negative men and women

Study shows cholesterol rafts can shepherd genetic payloads into cancer cells

Researchers develop new guidelines to treat recently diagnosed multiple myeloma patients

New born neurons as a therapeutic strategy: an interview with Mi-Hyeon Jang, Mayo Clinic in Rochester, Minnesota

Inovio Pharmaceuticals reports release of phase II clinical trial results of ChronVac-C

New research discovery in mosquitoes could lead to possible tools for controlling malaria

New research shows how metabolism and physiology are connected to diet

Researchers identify HNF1B gene that can increase risk of ovarian cancer

Inflammation and epigenetics: an interview with Dr Belkina and Dr Denis, Boston University School of Medicine

Researchers shed new light on role of methylation in gene expression

Academic medical centers launch ASD sub-registry within ResearchMatch

UCI study finds novel molecular mechanism that helps trigger formation of long-term memory

LMU researchers identify microRNA that offers promising target for new therapies

Epizyme receives patent for drug candidate for genetically defined type of non-Hodgkin lymphomas

Two genes associated with rare autism-related disorders linked to general forms of autism: Study

Gene LY86 identified as likely contributor to obesity

Cocaine can be lethal for people living with HIV

Study provides new insights about polycystic ovarian syndrome, insulin resistance

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