Molecule News and Research

RSS

Apolipoproten E appears to be new potential druggable target for Alzheimer's

Apolipoproten E is a major genetic risk factor for the development of Alzheimer's disease, yet the protein tends to be understudied as a potential druggable target for the mind-robbing neurodegenerative disease.

13 Jun 2019

New technology harnesses bacterial jumping genes for precise DNA integration

A new discovery by researchers at Columbia University Vagelos College of Physicians and Surgeons could fix one of the major shortcomings of current gene-editing tools, including CRISPR, and offer a powerful new approach for genetic engineering and gene therapy.

13 Jun 2019

Scientists discover weakness in common cold virus

Scientists have discovered a weakness on the surface of the viruses that cause a multitude of illnesses.

12 Jun 2019

Berkeley Lights and Amyris collaborate to improve testing of microbial strains

Berkeley Lights, Inc., the leader in digital cell biology, and Amyris, Inc., a leader in the development and production of sustainable ingredients for the Health & Wellness, Clean Beauty, and Flavors & Fragrances markets, announced today that they have entered into a collaboration focused on improving the production of high-value, small molecule, natural products from Amyris' microbial strains.

From Bruker Cellular Analysis 12 Jun 2019

Chemists build rich collection of natural product-like macrocycles for drug discovery

Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class.

12 Jun 2019

Fibrinogen a key player in health and disease, says new study

A new study from the University of Alberta demonstrated that the blood clotting protein called fibrinogen also regulates MMP-2, an enzyme involved in immunity and in clot formation inside blood vessels. Prolonged MMP-2 inhibition could potentially produce a deficiency state with severe consequences.

12 Jun 2019

Researchers identify macrophages' pathway to nurture PTEN-deficient glioblastoma

A common genetic deficiency empowers glioblastoma to broadcast a molecular message to the wrong type of immune cell, summoning macrophages that protect and nurture the brain tumor instead of attacking it, researchers at The University of Texas MD Anderson Cancer Center report in Cancer Cell.

11 Jun 2019

Proteasome inhibitors show potential for combating multidrug-resistant malaria

Proteasome inhibitors have significant promise as components of novel combination therapies to treat multidrug-resistant malaria, according to a study published June 6 in the open-access journal PLOS Pathogens by David Fidock, Caroline Ng, and Barbara Stokes of Columbia University Irving Medical Center, Matthew Bogyo of Stanford University School of Medicine, and colleagues.

From PLOS ONE 10 Jun 2019

EAF2000 advances complex charged molecule studies

Postnova Analytics reports on growing use of its pioneering EAF2000 system to separate and characterize complex proteins, antibodies and viruses as well as charged nanoparticles, colloids and polymers.

From Postnova Analytics 10 Jun 2019

Novel radiotracer can identify nearly 30 types of malignant tumors

A novel class of radiopharmaceuticals has proven effective in non-invasively identifying nearly 30 types of malignant tumors, according to research published in the June issue of The Journal of Nuclear Medicine.

10 Jun 2019

Scientists develop faster, easier method for making amino acid chains

Scientists often build new protein molecules by stringing groups of amino acids together. These amino acid chains, called polypeptides, are the building blocks needed in drug development and the creation of new biomaterials.

7 Jun 2019

Researchers study molecular mechanism of interplay of clock proteins for circadian oscillation

Organisms on this planet, including human beings, exhibit a biological rhythm that repeats about every 24 h to adapt to the daily environmental alteration caused by the rotation of the earth.

7 Jun 2019

Study offers hope to slow down or prevent progression of Parkinson’s

Results from a study published today looking at a molecule targeting clumps of alpha-synuclein, a key protein linked to Parkinson’s, offers hope that it may be possible to slow down or prevent the progression of the condition in humans.

6 Jun 2019

Bioactive hydrogel promises faster wound healing

A new study published in the journal 'Science Advances' presents the use of a novel tissue engineering material composed of bioactive injectable hydrogel to speed up the rate of healing in wounded tissues.

6 Jun 2019

Brush your teeth and use floss to slow down Alzheimer's

The researchers have determined that gum disease (gingivitis) plays a decisive role in whether a person develops Alzheimer´s or not.

3 Jun 2019

Researcher develops new computational statistical methodologies to deal with diffusion-MRI data

In her doctoral thesis at University of Jyväskylä, M.Sc. Jia Liu has developed and implemented a series of new computational statistical methodologies to deal with diffusion-MRI data.

3 Jun 2019

Young eczema sufferers infected with common skin bacterium are at higher risk of food allergy

In a new study published today in the Journal of Allergy and Clinical Immunology, scientists from King's College London have found that young children with severe eczema infected with Staphylococcus aureus bacterium, are at a higher risk of developing a food allergy.

31 May 2019

Scientific discovery may lead to a treatment for lupus

A team of scientists has uncovered the structure of a regulatory complex that is involved in the release of cytokines and can be inhibited to treat lupus.

31 May 2019

Powerful separation technique opens door to characterizing complex samples

From Postnova Analytics 31 May 2019

Research identifies new target that may help develop new treatments for common STD

Research led by Ashok Aiyar, PhD, Associate Professor of Microbiology, Immunology and Parasitology at LSU Health New Orleans School of Medicine, has identified a target that may lead to the development of new treatments for the most common sexually transmitted infection in the US.

31 May 2019