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Researchers develop new methods that improve quality of myocardial perfusion imaging

New methods that enhance the quality of myocardial perfusion imaging were developed in a recent study completed at the University of Eastern Finland.

9 Sep 2014

Cholera against cholera: an interview with Dr Bruce Turnbull, University of Leeds

Cholera bacteria, and other types of bacteria that cause diarrheal diseases, infect your intestines where they release AB5 protein toxins – that is they have a single toxic A-subunit that is linked to a pentamer of B-subunits that act as the delivery vehicle to transport the A-subunit into the cells.

8 Sep 2014

Transparency Life receives SBIR program grant to fund Phase 2a proof-of-concept study for MS

Transparency Life Sciences, LLC (TLS), the world's first clinical-stage drug development company based on open innovation, today announced that it has received a Small Business Innovation Research (SBIR) program grant to fund a Phase 2a proof-of-concept study testing the utility of the ACE inhibitor lisinopril as an adjunctive therapy for multiple sclerosis (MS).

8 Sep 2014

FDA provides QIDP designation to Debiopharm’s Debio 1450 for treatment of ABSSSI

Debiopharm Group™(Debiopharm), a Swiss-based global biopharmaceutical company developing prescription drugs that target unmet medical needs including anti-infective and oncology therapeutics as well as companion diagnostics, today announced that the US Food and Drug Administration (FDA) has designated its anti-infectious agent Debio 1450 as a Qualified Infectious Disease Product (QIDP) for the treatment of acute bacterial skin and skin structure infections (ABSSSI).

4 Sep 2014

Positive clinical data for first procedural therapy to treat type 2 diabetes from Fractyl

Fractyl Laboratories Inc. today announced positive clinical data for the first procedural therapy to directly treat the underlying digestive causes of insulin resistance in patients with uncontrolled type 2 diabetes.

4 Sep 2014

Sepsis patients more likely to survive when treated at hospital with higher volume of cases

Patients with sepsis, one of the most time-sensitive and hard-to-detect illnesses in medicine, are more likely to survive the life-threatening condition when treated at a hospital that sees a higher volume of sepsis cases.

4 Sep 2014

Ludwig, CRI collaborate with VentiRx to conduct clinical trial with motolimod and immunotherapy agents

The nonprofits Ludwig Cancer Research (Ludwig) and the Cancer Research Institute (CRI) announced today an agreement with VentiRx Pharmaceuticals Inc., a clinical stage biopharmaceutical company, to conduct a clinical trial with motolimod (VTX-2337) combined with other immunotherapy agents available to Ludwig and CRI through other industry partnerships.

4 Sep 2014

Pacific Edge signs agreement with SCPMG to evaluate Cxbladder User Program

Pacific Edge Ltd, a cancer diagnostics company, has signed an agreement with Southern California Permanente Medical Group (SCPMG) to research its User Program to evaluate its bladder cancer technology Cxbladder within the clinical settings of Kaiser Permanente's health care network.

3 Sep 2014

Measuring levels of sex hormones in patients' blood may identify risk of sudden cardiac arrest

Measuring the levels of sex hormones in patients' blood may identify patients likely to suffer a sudden cardiac arrest, a heart rhythm disorder that is fatal in 95 percent of patients.

3 Sep 2014

Researchers identify different types of tuberculosis using new genetic barcode

Doctors and researchers will be able to easily identify different types of tuberculosis (TB) thanks to a new genetic barcode devised by scientists from the London School of Hygiene & Tropical Medicine.

3 Sep 2014

Cepheid releases Xpert Flu/RSV XC for accurate determination of Flu A, Flu B and RSV infection

Cepheid announced today the release of Xpert® Flu/RSV XC, an on-demand molecular test for rapid, accurate and reliable determination of Flu A, Flu B, and differentiation of RSV infection.

2 Sep 2014

Two fully automated molecular testing systems for blood and plasma donor screening launched by Roche

Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today the commercial availability of the cobas 6800/8800 Systems, two integrated and fully automated molecular testing systems for blood and plasma donor screening, in markets accepting the CE mark. The cobas 6800/8800 Systems offer the fastest time to results with the highest throughput available, along with the longest walk-away time, enabling laboratory staff to drive increased workflow efficiencies, while adapting to their ever-changing testing demands.

From Roche Sequencing and Life Science 2 Sep 2014

American scientists develop another groundbreaking click concept: SuFEx

The coupling of molecular building blocks nearly as easy as “snapping” them together can be realized by means of the “click chemistry” tool kit. American scientists have now introduced another achievement for the click concept in the journal Angewandte Chemie: the sulfur fluoride exchange reaction (SuFEx) can be used to form robust inorganic bridges between carbon centers and opens up a fully unexplored area of chemistry with countless new molecules that could form the basis for new drugs, diagnostics, plastics, “intelligent” materials, and many other products.

2 Sep 2014

New genetic barcode helps identify different types of tuberculosis

2 Sep 2014

ACCA Clinical Decision-Making Toolkit mobile app helps make quick and correct decision

The ACCA Clinical Decision-Making Toolkit mobile app is now available on the App Store and Google Play. When dealing with acute cardiovascular diseases, a few seconds can make the difference and instant access to the best recommendations can save lives.

30 Aug 2014

Freiburg biochemists discover new mechanisms of brain disease

The failing in the work of nerve cells: An international team of researchers led by Prof. Dr. Chris Meisinger from the Institute of Biochemistry and Molecular Biology of the University of Freiburg has discovered how Alzheimer's disease damages mitochondria, the powerhouses of the cell.

29 Aug 2014

Pixcelldata, eX-Path announce major new deal in advance of ECP 2014

Pixcelldata, the innovative Irish developer of digital pathology management and collaboration software has announced a major new deal with Dutch based eX-Path, global providers of tele-pathology services, founded by renowned pathology expert, Dr. Marius Nap.

29 Aug 2014

CTC clusters cause metastasis

Circulating tumor cell (CTC) clusters - clumps of from 2 to 50 tumor cells that break off a primary tumor and are carried through the bloodstream - appear to be much more likely to cause metastasis than are single CTCs, according to a study from investigators at the Massachusetts General Hospital Cancer Center.

29 Aug 2014

New treatment fights respiratory syncytial virus

The New England Journal of Medicine published research results on Aug. 21 from a clinical trial of a drug shown to safely reduce the viral load and clinical illness of healthy adult volunteers intranasally infected with respiratory syncytial virus (RSV).

29 Aug 2014

TGen to lead first-in-patient clinical trial studies to test novel drugs for glioblastoma

SIn 2012, The Ben & Catherine Ivy Foundation awarded $10 million in grants for two groundbreaking brain cancer research projects at the Translational Genomics Research Institute. One of those projects has officially received the final regulatory approval from University of California, San Francisco, which means patient enrollment for the trial can begin.

29 Aug 2014

Diagnostics News and Research

Researchers develop new methods that improve quality of myocardial perfusion imaging

Cholera against cholera: an interview with Dr Bruce Turnbull, University of Leeds

Transparency Life receives SBIR program grant to fund Phase 2a proof-of-concept study for MS

FDA provides QIDP designation to Debiopharm’s Debio 1450 for treatment of ABSSSI

Positive clinical data for first procedural therapy to treat type 2 diabetes from Fractyl

Sepsis patients more likely to survive when treated at hospital with higher volume of cases

Ludwig, CRI collaborate with VentiRx to conduct clinical trial with motolimod and immunotherapy agents

Pacific Edge signs agreement with SCPMG to evaluate Cxbladder User Program

Measuring levels of sex hormones in patients' blood may identify risk of sudden cardiac arrest

Researchers identify different types of tuberculosis using new genetic barcode

Cepheid releases Xpert Flu/RSV XC for accurate determination of Flu A, Flu B and RSV infection

Two fully automated molecular testing systems for blood and plasma donor screening launched by Roche

American scientists develop another groundbreaking click concept: SuFEx

New genetic barcode helps identify different types of tuberculosis

ACCA Clinical Decision-Making Toolkit mobile app helps make quick and correct decision

Freiburg biochemists discover new mechanisms of brain disease

Pixcelldata, eX-Path announce major new deal in advance of ECP 2014

CTC clusters cause metastasis

New treatment fights respiratory syncytial virus

TGen to lead first-in-patient clinical trial studies to test novel drugs for glioblastoma

Event guide: 16th Clinical Biomarkers & CDx Summit Europe eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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