Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Diabetic women more likely to report low overall sexual satisfaction

Women with diabetes are just as likely to be interested in, and engage in, sexual activity as non-diabetic women, but they are much more likely to report low overall sexual satisfaction, according to a UCSF study.

26 Jul 2012

Roche Diabetes Care announces availability of new ACCU-CHEK Nano SmartView System

Roche Diabetes Care, makers of ACCU-CHEK products and services, is pleased to announce the availability of the new, user-friendly ACCU-CHEK Nano SmartView System.

26 Jul 2012

Scientists use inactive, fat rats to study juvenile obesity

Childhood obesity has nearly tripled in the past three decades, and by 2009, 17 percent of those 2-19 years of age were classified as obese. If actions against childhood obesity do not take place it is likely that today's children could be the first generation in over a century to experience a decline in life expectancy due to the epidemic of childhood obesity which leads to complications in later life.

25 Jul 2012

EC grants Marketing Authorisation to Boehringer Ingelheim and Lilly’s Jentadueto for diabetes

Boehringer Ingelheim and Eli Lilly and Company received Marketing Authorisation from the European Commission for Jentadueto which combines the DPP-4 inhibitor, linagliptin and metformin in a single tablet.

25 Jul 2012

Scientists identify mechanisms by which GLP-1 protects against kidney disease, diabetes

Scientists at Joslin Diabetes Center have identified biological mechanisms by which glucagon-like peptide-1 (GLP-1), a gut hormone, protects against kidney disease, and also mechanisms that inhibit its actions in diabetes.

24 Jul 2012

Linagliptin safe and effective for long-term management of type 2 diabetes

An extended trial of a drug for people with type 2 diabetes has confirmed that the oral DPP-4 inhibitor linagliptin is a safe and effective means of lowering glucose levels for up to 102 weeks, either on its own or in combination with other selected oral anti-diabetic medication.

23 Jul 2012

Mother's exposure to air pollution increases risk of obesity and insulin resistance in offspring

Pregnant mice exposed to high levels of air pollution gave birth to offspring with a significantly higher rate of obesity and insulin resistance in adulthood than those that were not exposed to air pollution. This effect seemed especially prevalent in male mice, which were heavier regardless of diet. These findings, published online in the FASEB Journal, suggests a link between diesel exhaust exposure in utero and bulging waistlines in adulthood.

20 Jul 2012

Short-term infection with intestinal worms may provide long-term protection against TID

Short-term infection with intestinal worms may provide long-term protection against type I diabetes (TID), suggests a study conducted by William Gause, PhD, and colleagues at the University of Medicine and Dentistry of New Jersey-New Jersey Medical School.

20 Jul 2012

New blood sugar monitor: An interview with Sherita Hill Golden

Type 1 diabetes is a disorder in which the body makes proteins (antibodies) against the cells in the pancreas that produce insulin, destroying those cells. As a result, individuals are unable to secrete insulin to normalize blood sugar and hyperglycemia results.

20 Jul 2012

Conatus, University of Alberta initiate islet cell transplant Phase I/II trial of emricasan for diabetes

Conatus Pharmaceuticals Inc. and the University of Alberta announced today the treatment of the first patient in an investigator-initiated islet cell transplant Phase I/II trial of emricasan (IDN-6556), a pan-caspase inhibitor.

20 Jul 2012

Diabetes linked to onset of Alzheimer's disease

Researchers from the University of Medicine and Dentistry of New Jersey (UMDNJ), collaborating with scientists from Northwestern University in Illinois, have provided direct experimental evidence that diabetes is linked to the onset of Alzheimer's disease.

19 Jul 2012

Research explains why exercise is beneficial for heart function in type 2 diabetes

A detailed study of heart muscle function in mice has uncovered evidence to explain why exercise is beneficial for heart function in type 2 diabetes. The research team, led by scientists at the Johns Hopkins University School of Medicine, found that greater amounts of fatty acids used by the heart during stressful conditions like exercise can counteract the detrimental effects of excess glucose and improve the diabetic heart's pumping ability in several ways.

18 Jul 2012

c-Kit receptor plays critical role in development and function of insulin-producing beta cells

Scientists from Western University in London, Canada and the Children's Health Research Institute, an Institute within the Lawson Health Research Institute, have identified the critical role of a receptor called c-Kit in the development and function of insulin-producing beta cells, making it an exciting therapeutic target for the management of diabetes.

18 Jul 2012

Combination of obesity and vitamin D deficiency may increase risk of diabetes

The combination of obesity and vitamin D deficiency may put people at even greater risk of insulin resistance than either factor alone, according to new research from the Drexel University School of Public Health recently published early online in the journal Diabetes Care.

18 Jul 2012

How does exercise improve heart function in diabetics?

A detailed study of heart muscle function in mice has uncovered evidence to explain why exercise is beneficial for heart function in type 2 diabetes.

18 Jul 2012

Research reveals how metformin reduces HCC risk

For every year that a patient with diabetes takes metformin, their risk for hepatocellular carcinoma reduces, say the authors of a study that also sheds light on the cellular pathway it uses.

16 Jul 2012

Antipsychotic use in pregnancy should be closely monitored

Use of any type of antipsychotic during pregnancy increases the risk for women developing gestational diabetes, show Swedish study results that also indicate a link between antipsychotics and a risk for giving birth to a small for gestational age infant.

13 Jul 2012

Manipulating retinal recipient microenvironment impacts photoreceptor cell transplantation

A research team in the United Kingdom has found that insulin-like growth factor (IGF1) impacts cell transplantation of photoreceptor precursors by manipulating the retinal recipient microenvironment, enabling better migration and integration of the cells into the adult mouse retina.

12 Jul 2012

Arrowhead initiates Adipotide Phase 1 trial in obesity

Arrowhead Research Corporation, a targeted therapeutics company, today announced that the first patient has been dosed in a Phase 1 clinical trial with Adipotide, a new class of treatment for obesity.

11 Jul 2012

Connections between daily stressors of police work and obesity, suicide

The daily psychological stresses that police officers experience in their work put them at significantly higher risk than the general population for a host of long-term physical and mental health effects. That's the overall finding of a major scientific study of the Buffalo Police Department called Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) conducted over five years by a University at Buffalo researcher.

11 Jul 2012

Insulin News and Research

Further Reading

Diabetic women more likely to report low overall sexual satisfaction

Roche Diabetes Care announces availability of new ACCU-CHEK Nano SmartView System

Scientists use inactive, fat rats to study juvenile obesity

EC grants Marketing Authorisation to Boehringer Ingelheim and Lilly’s Jentadueto for diabetes

Scientists identify mechanisms by which GLP-1 protects against kidney disease, diabetes

Linagliptin safe and effective for long-term management of type 2 diabetes

Mother's exposure to air pollution increases risk of obesity and insulin resistance in offspring

Short-term infection with intestinal worms may provide long-term protection against TID

New blood sugar monitor: An interview with Sherita Hill Golden

Conatus, University of Alberta initiate islet cell transplant Phase I/II trial of emricasan for diabetes

Diabetes linked to onset of Alzheimer's disease

Research explains why exercise is beneficial for heart function in type 2 diabetes

c-Kit receptor plays critical role in development and function of insulin-producing beta cells

Combination of obesity and vitamin D deficiency may increase risk of diabetes

How does exercise improve heart function in diabetics?

Research reveals how metformin reduces HCC risk

Antipsychotic use in pregnancy should be closely monitored

Manipulating retinal recipient microenvironment impacts photoreceptor cell transplantation

Arrowhead initiates Adipotide Phase 1 trial in obesity

Connections between daily stressors of police work and obesity, suicide

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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