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Experimental drug improves survival rate of majority of lung cancer patients compared to standard chemotherapy

In global clinical trials, patients with advanced metastatic lung cancer who were treated with a targeted immunotherapy drug lived significantly longer and with fewer side effects than those who received standard second-line chemotherapy, according to a new Kaiser Permanente study published today in the journal The Lancet.

15 Mar 2016

CardiacAssist's new TandemLung oxygenator receives FDA clearance

CardiacAssist, Inc. today announced that it has received 510(k) clearance from the U.S. Food and Drug Administration for its new TandemLung oxygenator, a medical device that acts as an artificial lung to infuse oxygen and remove carbon dioxide from the blood.

15 Mar 2016

DelMar's VAL-083 receives FDA orphan drug designation for treatment of medulloblastoma

DelMar Pharmaceuticals, Inc., announced today that the FDA Office of Orphan Products Development (OOPD) has granted orphan drug designation for its lead product candidate, VAL-083, in the treatment of medulloblastoma.

15 Mar 2016

New drug shows promise against mesothelioma

A new drug is showing promise as a treatment for mesothelioma - one of the most lethal cancers of all.

15 Mar 2016

New drug could transform treatment of metastatic triple negative breast cancer

A team of investigators from Houston Methodist Research Institute may have transformed the treatment of metastatic triple negative breast cancer by creating the first drug to successfully eliminate lung metastases in mice.

15 Mar 2016

Combination drug therapy may stop KRAS-mediated lung adenocarcinoma

Researchers on Mayo Clinic's Florida campus have shut down one of the most common and lethal forms of lung cancer by combining the rheumatoid arthritis drug auranofin with an experimental targeted agent.

15 Mar 2016

Anticancer drug restores hearing in neurofibromatosis patients

In a small clinical study with an anticancer drug that halts blood vessel growth, a handful of people with neurofibromatosis type 2 (NF2) and hearing loss had restoration of hearing.

15 Mar 2016

Liposomes can be potential candidates for drug delivery to constricted coronary arteries

Liposomes are currently used as drug delivery vehicles but recognized by the immune system. Scientists from the universities of Basel and Fribourg have shown that special artificial liposomes do not elicit any reaction in human and porcine sera as well as pigs.

14 Mar 2016

Researchers exploring ways to prevent radiation-induced cancer risk in astronauts

NASA limits an astronaut's radiation exposures to doses that keep their added risk of fatal cancer below 3 percent. Unfortunately, that ceiling restricts the time an astronaut may spend in space, which in turn restricts the ability to perform longer missions, say a mission to Mars.

14 Mar 2016

New evidence-based guideline to tackle synoptic reporting of bone marrow data

Clinicians and patients alike will benefit as the Pathology and Laboratory Quality Center of the College of American Pathologists releases a new evidence-based guideline that tackles the complexities of reporting findings from bone marrow specimens.

14 Mar 2016

Beta-blockers could have potential benefit for COPD patients

Beta-blockers could be used to reduce the risk of chronic obstructive pulmonary disease (COPD) exacerbations, according to new findings.

13 Mar 2016

FDA approves Xalkori (crizotinib) to treat patients with ROS-1 positive NSCLC

The U.S. Food and Drug Administration today approved Xalkori (crizotinib) to treat people with advanced (metastatic) non-small cell lung cancer (NSCLC) whose tumors have an ROS-1 gene alteration. Xalkori is the first and only FDA approved treatment for patients with ROS-1 positive NSCLC.

13 Mar 2016

Advances in new scanning technology may provide a clearer picture of lung disease

New scanning technology which will give a much clearer picture of lung disease has taken a major step forward thanks to scientists at The University of Nottingham.

11 Mar 2016

Conserved gene can act to inhibit lung cancer development, study finds

Scientists believe that "conserved" genes — those found in life forms that range from bacteria to plants, insects and humans — perform vital biological functions across species. And limited research on one of those genes, Nitrilase 1 (Nit1), suggested it acts to inhibit cancer development.

11 Mar 2016

Southampton researchers explore ADAM33 gene's association with asthma, airway 'twitchiness'

Researchers at the University of Southampton are to study why some people are more likely to develop asthma.

11 Mar 2016

Patients with early-stage NSCLC and low SMARCA4 expression may benefit from platinum-based chemotherapy

The activity level of a particular gene in lung tumors might identify lung-cancer patients who will likely be helped by a particular chemotherapy regimen given to prevent recurrence after surgery.

11 Mar 2016

Excess comorbidity flagged in MS patients

Patients with multiple sclerosis have more comorbidities than would be expected for their age, even at the time of diagnosis, say researchers.

10 Mar 2016

Single-step, rapid life-saving solution for pneumothorax treatment

Pneumothorax is a medical emergency: the collection of air in the pleural space separating the lung from the chest wall, causing it to collapse and resulting in suffocation. Pneumothorax is caused by chest trauma, and is believed to be responsible for over a third of preventable deaths on the battlefield and in terror attacks.

10 Mar 2016

CYP3A7 gene may over-activate metabolism, reduce effectiveness of cancer treatments

Some patients with breast cancer, lung cancer and leukaemia seem to fare poorly after treatment because of the effects of a particular gene, a new study finds.

10 Mar 2016

Scientists discover novel drug candidate to treat breast cancer, lung cancer and melanoma

Using a new approach, scientists at The Scripps Research Institute and collaborating institutions have discovered a novel drug candidate that could be used to treat certain types of breast cancer, lung cancer and melanoma.

10 Mar 2016

Lungs News and Research

Experimental drug improves survival rate of majority of lung cancer patients compared to standard chemotherapy

CardiacAssist's new TandemLung oxygenator receives FDA clearance

DelMar's VAL-083 receives FDA orphan drug designation for treatment of medulloblastoma

New drug shows promise against mesothelioma

New drug could transform treatment of metastatic triple negative breast cancer

Combination drug therapy may stop KRAS-mediated lung adenocarcinoma

Anticancer drug restores hearing in neurofibromatosis patients

Liposomes can be potential candidates for drug delivery to constricted coronary arteries

Researchers exploring ways to prevent radiation-induced cancer risk in astronauts

New evidence-based guideline to tackle synoptic reporting of bone marrow data

Beta-blockers could have potential benefit for COPD patients

FDA approves Xalkori (crizotinib) to treat patients with ROS-1 positive NSCLC

Advances in new scanning technology may provide a clearer picture of lung disease

Conserved gene can act to inhibit lung cancer development, study finds

Southampton researchers explore ADAM33 gene's association with asthma, airway 'twitchiness'

Patients with early-stage NSCLC and low SMARCA4 expression may benefit from platinum-based chemotherapy

Excess comorbidity flagged in MS patients

Single-step, rapid life-saving solution for pneumothorax treatment

CYP3A7 gene may over-activate metabolism, reduce effectiveness of cancer treatments

Scientists discover novel drug candidate to treat breast cancer, lung cancer and melanoma

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