Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

Using native microbes as chassis for transgene delivery in live bacterial therapeutics

Residing within the human gut are trillions of bacteria and other microorganisms that can impact a variety of chronic human ailments, including obesity, type 2 diabetes, atherosclerosis, cancer, non-alcoholic fatty liver disease and inflammatory bowel disease.

4 Aug 2022

UVA researchers receive $15 million from LeDucq Foundation to advance understanding of atherosclerosis

The Boston-based LeDucq Foundation has awarded $15 million to researchers at UVA Health and their collaborators to advance our understanding of atherosclerosis, or hardening of the arteries, and find better ways to treat it.

3 Aug 2022

IRB Barcelona researchers discover genetic drivers of clonal hematopoiesis

Clonal hematopoiesis is a biological process in which a blood stem cell (the population that gives rise to a variety of blood cell types) acquires an advantageous mutation and outgrows neighboring cells.

2 Aug 2022

Most familial hypercholesterolemia patients remain undiagnosed, analysis reveals

The Family Heart Foundation, a leading research and advocacy organization, completed an analysis of its large U.S. Family Heart Database showing that while the percentage of patients diagnosed with familial hypercholesterolemia (FH) has increased substantially since 2016, most remain undiagnosed.

27 Jul 2022

Genetic tests do little to accurately identify cardiovascular risks compared to simple health assessment

A genetic risk for heart disease is far less predictive of problems than actual lifestyle risk factors such as high blood pressure, high cholesterol and diabetes -- even among younger adults.

26 Jul 2022

Scientists discover a surprising link between mitochondria, inflammation and DNMT3A and TET2 genes

Mitochondria are known as cells' powerhouses, but mounting evidence suggests they also play a role in inflammation. Scientists from the Salk Institute and UC San Diego published new findings in Immunity on July 26, 2022, where they examined human blood cells and discovered a surprising link between mitochondria, inflammation and DNMT3A and TET2 - two genes that normally help regulate blood cell growth but, when mutated, are associated with an increased risk of atherosclerosis.

26 Jul 2022

Study suggests a possible treatment approach for cancer and cardiovascular disease

A key molecule for cancer metastasis has been identified as a molecule already known for its involvement in cardiovascular disease, suggesting a possible treatment approach for both diseases simultaneously.

25 Jul 2022

Adopting a healthy cardiovascular lifestyle may lower stroke risk

Genes and lifestyle factors together play a role in stroke risk. However, even for people at high risk for stroke, adopting a healthy cardiovascular lifestyle may significantly lower the risk of stroke in their lifetime, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

20 Jul 2022

Cardiovascular mortality has declined over the past two decades, but disparities persist

Research supported by the National Institutes of Health shows that cardiovascular-related deaths have declined over the past two decades, but disparities remain.

19 Jul 2022

Long-established drug for angina pectoris shows anti-inflammatory effect, reduces atherosclerotic plaques

A drug used in the clinical treatment of angina symptoms also has an anti-inflammatory effect and reduces atherosclerotic plaques in blood vessels - thereby reducing the risk of heart attack or stroke.

14 Jul 2022

Black individuals may be more vulnerable to atherosclerosis early in life than young Hispanic adults

A unique Mount Sinai study focused on a multi-ethnic, underserved community in New York City shows that young Black adults are twice as likely to have atherosclerosis as similarly situated young Hispanic adults.

11 Jul 2022

Exploring association of fetal and infant weight growth patterns with impaired arterial health

A new study examined the association of weight growth patterns during infancy and fetal periods with carotid distensibility and cIMT in children who are 10 years of age.

1 Jul 2022

Study finds higher risk of cardiovascular disease among adult cancer survivors

Adult survivors of cancer have a higher risk of heart failure and other cardiovascular diseases (CVD) later in life than adults without cancer, according to results of a large study led by Johns Hopkins Medicine researchers.

28 Jun 2022

Biodegradable nanomaterials can take images and deliver medicine to combat peripheral arterial disease

A University of Texas at Arlington bioengineer is leading a project that will develop biodegradable nanomaterials that will take pictures and deliver medicine to combat peripheral arterial disease (PAD).

24 Jun 2022

Pregnant women with PCOS have higher risk for heart problems during delivery

A common hormone disorder among women of reproductive age has been linked to an increased risk of adverse cardiovascular events and pregnancy outcomes at the time of birth, according to a new study led by Johns Hopkins Medicine researchers.

16 Jun 2022

Uncontrolled diabetes can increase the risk of heart failure progression, study finds

Among older adults with early stage - also known as preclinical - heart failure, uncontrolled diabetes can substantially increase the risk of heart failure progression, according to a new Johns Hopkins-led study.

14 Jun 2022

One in 500 men may carry an extra X or Y chromosome which could increase risk of several diseases

Around one in 500 men could be carrying an extra X or Y chromosome – most of them unaware – putting them at increased risk of diseases such as type 2 diabetes, atherosclerosis and thrombosis, say researchers at the universities of Cambridge and Exeter.

10 Jun 2022

Cofilin could be a potential target for mitigating atherosclerosis at early stage, finds study

A joint research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) and Queen Mary University of London (QMUL) has discovered the molecular mechanisms of how pathological condition-mimicking mechanical stimuli lead to the early progression of atherosclerosis, a leading cause of vascular disease worldwide.

8 Jun 2022

Coffee consumption may reduce the risk of acute kidney injury

If you need another reason to start the day drinking a cup of joe, a recent study by Johns Hopkins Medicine researchers has revealed that consuming at least one cup of coffee a day may reduce the risk of acute kidney injury (AKI) when compared to those who do not drink coffee.

2 Jun 2022

Researchers show how electrical stimulation of the vagus nerve in inflammation promotes healing

The nervous system is known to communicate with the immune system and regulate inflammation in the body. Researchers at Karolinska Institutet in Sweden now show how electrical activation of a specific nerve can promote healing in acute inflammation.

31 May 2022