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UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

Researchers at the University of Arizona Health Sciences are closer to developing a safe and effective non-opioid pain reliever after a study showed that a new compound they created reduces the sensation of pain by regulating a biological channel linked to pain.

10 Nov 2021

Ion channel mechanosensor plays a key role in regulating the speed of skin wound healing

PIEZO1, an ion channel mechanosensor found within cells, has been revealed to play a key role in regulating the speed of skin wound healing by researchers at the University of California, Irvine.

10 Nov 2021

Experts discover novel tool to explore ways to advance cancer treatment

Researchers at Queen’s University Belfast have discovered a new tool, which will help to investigate more effective forms of cancer treatment.

9 Nov 2021

Inhalation of CO2 after a traumatic experience enhances fear memory in mice

The inhalation of carbon dioxide (CO2) by mice a few hours after they formed a new fearful memory makes that memory stronger, so that the mice show more distress when they are prompted to 'retrieve' (ie, recall) it.

8 Nov 2021

Scientists document the spread of atrial fibrillation risk gene across continents and over centuries

University of Utah Health scientists have documented the spread of a disease gene across continents and over centuries.

8 Nov 2021

MIT researchers identify link between MEF2 gene and cognitive resilience in older individuals

Many people develop Alzheimer's or other forms of dementia as they get older. However, others remain sharp well into old age, even if their brains show underlying signs of neurodegeneration.

3 Nov 2021

How cellular clocks regulate cardiac physiology

In this interview, News-Medical speaks to research associate Dr. Alessandra Stangherlin about her latest research that provided new insights into the circadian rhythm of the heart.

2 Nov 2021

U-M researchers target a protein channel in the cell’s lysosome to selectively kill cancer cells

Cancer treatments necessarily target unchecked cell growth, and selectively kill cancer cells while sparing normal cells and avoiding general toxicity in the human body.

20 Oct 2021

The neutralization potential of nanobodies against SARS-CoV-2

A recent review describes the role of nanobodies as a new class of recombinant antibodies that are used in the treatment of COVID-19.

20 Oct 2021

New method to study the nuclear pore complex directly inside cells

Context matters. It's true for many facets of life, including the tiny molecular machines that perform vital functions inside our cells.

18 Oct 2021

Research reveals how daily circadian rhythms help to change heart function

A new study has shown how circadian rhythms in heart cells help to change heart function over the course of the day and may explain why shift workers are more vulnerable to heart problems.

18 Oct 2021

Study reveals unique molecular mechanisms of stomach’s acid pump

Nagoya University researchers and colleagues have improved understanding of the molecular mechanisms of a key protein that makes the stomach acidic. Their findings, published in the journal Nature Communications, could lead to better drugs for stomach ulcers and shed light on the functions of similar proteins across the human body.

15 Oct 2021

Study reveals the zoonotic potential of the rat Sialodacryoadenitis virus

A new review aimed to describe the current state of knowledge on Sialodacryoadenitis virus, along with its characteristics and potential zoonotic threat.

13 Oct 2021

New study finds SARS-CoV-2 causes retinal infection

Can coronavirus disease 2019 (COVID-19) affect the eye? New research suggests the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can enter the eye and infect photoreceptor and retinal ganglion cells. In addition, SARS-CoV-2 infection increases the expression of several inflammatory genes, including the cytokine interleukin 33 (IL33), which is linked to COVID-19 disease and retinal degeneration.

13 Oct 2021

New method to diagnose anosmia

In a recent study, researchers discuss a new method of tracking the Nav1.7 channel to reduce the reliance on more invasive diagnostic measures.

13 Oct 2021

Planar cell polarity pathway found to be responsible for the formation and maintenance of synapses

Within the brain and other parts of the nervous system, synapses are key junctional points in between neurons (the nerve cells) where critical signals are transmitted. More specifically, the "glutamatergic" synapses are the prime "excitatory" synapse junctions that neurons use to activate each other and are known to have broad diversity in size and shape.

7 Oct 2021

Researchers develop nanoparticles delivering STING agonists for intravenous cancer immunotherapy

Cancer immunotherapy seeks to turn "cold" tumors into "hot" tumors––those that respond to immunotherapy––by awakening and enlisting the body's own immune system.

30 Sep 2021

SARS-CoV-2 viroporin activity impacts viral infectivity and pathogenicity

A team of researchers studied the two main viroporins of SARS-CoV-2, namely Orf3a and Envelope (E) protein, from a structural viewpoint.

29 Sep 2021

New analysis reveals distinct differences between molecular profiles of 3D and 2D cultured cells

Oncotarget published "Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells" which reported that to ascertain phenotypical differences between these two distinct culture conditions, these authors carried out a comparative proteomic analysis of a membrane fraction obtained from 3D- and 2D-cultured NSCLC model cell line NCI-H23.

29 Sep 2021

Radiation therapy for ventricular tachycardia may revert heart muscle cells to a younger state

Radiation therapy for ventricular tachycardia — a life-threatening irregular heart rhythm — appears to work by reverting heart muscle cells to a younger state, reducing the irregular rhythms, according to a new study from Washington University School of Medicine in St. Louis.

24 Sep 2021

Ion News and Research

UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

Ion channel mechanosensor plays a key role in regulating the speed of skin wound healing

Experts discover novel tool to explore ways to advance cancer treatment

Inhalation of CO2 after a traumatic experience enhances fear memory in mice

Scientists document the spread of atrial fibrillation risk gene across continents and over centuries

MIT researchers identify link between MEF2 gene and cognitive resilience in older individuals

How cellular clocks regulate cardiac physiology

U-M researchers target a protein channel in the cell’s lysosome to selectively kill cancer cells

The neutralization potential of nanobodies against SARS-CoV-2

New method to study the nuclear pore complex directly inside cells

Research reveals how daily circadian rhythms help to change heart function

Study reveals unique molecular mechanisms of stomach’s acid pump

Study reveals the zoonotic potential of the rat Sialodacryoadenitis virus

New study finds SARS-CoV-2 causes retinal infection

New method to diagnose anosmia

Planar cell polarity pathway found to be responsible for the formation and maintenance of synapses

Researchers develop nanoparticles delivering STING agonists for intravenous cancer immunotherapy

SARS-CoV-2 viroporin activity impacts viral infectivity and pathogenicity

New analysis reveals distinct differences between molecular profiles of 3D and 2D cultured cells

Radiation therapy for ventricular tachycardia may revert heart muscle cells to a younger state

Enhancing confidence in chemical ionization spectrometry data eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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