Nucleic Acid News and Research

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Delays in TB diagnosis often exceed WHO’s recommendations, shows study

Tuberculosis remains a rare disease in the United States, but when it does occur, delays in diagnosing it often exceed recommendations by the World Health Organization, according to a new report by Harvard Medical School researchers published March 22 in The Lancet Infectious Diseases.

24 Mar 2021

New guidelines outline key new actions to improve delivery of HIV testing, treatment and care

These guidelines provide new and updated recommendations on the use of point-of-care testing in children under 18 months of age and point-of-care tests to monitor treatment in people living with HIV; the treatment monitoring algorithm; and timing of antiretroviral therapy (ART) among people living with HIV who are being treated for tuberculosis.

23 Mar 2021

Researchers explore nanotechnology’s potential to deliver synergistic therapeutics for COVID-19

A team of scientists reviewed the nanoencapsulation approaches of synergistic compounds (Lectins, Caffeine, Cocoa, Flavonoids, Quercetin) and the role of nanotechnology in addressing the COVID-19 pandemic.

19 Mar 2021

Identifying druggable targets on an essential SARS-CoV-2 protein

In a research paper recently uploaded to the preprint server bioRxiv by Newman et al. (March 15th, 2021) the structure and role of one such protein: NSP13, is investigated, with two appealingly druggable targets being identified, possibly opening a new route towards a novel SARS-CoV-2 antiviral agent.

18 Mar 2021

Aptamer Group and Mologic enter commercial partnership to develop aptamer-based SARS-CoV-2 rapid antigen test

Aptamer Group, the developer of diagnostic and therapeutic Optimer™ reagents, today announced a commercial partnership with Mologic.

From Aptamer Group 18 Mar 2021

INTEGRA’s pipetting robot supports PCR-based HPV screening across France

Labs are increasingly choosing INTEGRA Biosciences’ liquid handling instruments to help them address growing workloads associated with Human papilloma virus (HPV) screening.

17 Mar 2021

The role of RNA capping of SARS-CoV-2 in immunity evasion

The SARS-CoV-2 pathogen successfully uses multiple immune evasion mechanisms to achieve infection within its host. An intriguing new study describes one such process, which may help develop drugs to counteract the virus more effectively.

16 Mar 2021

Promega launches XpressAmp™ Direct Amplification Reagents

Promega Corporation has released XpressAmp™ Direct Amplification Reagents that facilitate RNA extraction-free sample preparation that is automation-friendly.

From Promega Corporation 11 Mar 2021

QCMD to use RNAssist’s virusPHIX-P9™ Biomolecule Stabilization Technology in its SARS-CoV-2 antigen EQA scheme

In a further development of the collaboration between QCMD and RNAssist, QCMD will use the universal biological sample stabilization virusPHIX-P9™.

From Rapid Labs Ltd 10 Mar 2021

Join a brief introduction to Nucleic Acid Gel Stains: exploring safer dyes and Non-UV imaging solutions

At Pittcon, we are featuring our advanced Gel Box Illuminator that provides clear visualization of DNA after electrophoresis. It is optimized for use with both Red and Green dyes (no EtBr) and generates no UV radiation. For more information go to: Gel Box Illuminator

From OMEC Medical 9 Mar 2021

Apoptosis is an important mediator of pathogenesis in animal coronavirus infection

A new paper in the journal Life presents an early review of the viral factors involved in initiating and effecting apoptosis within infected cells.

8 Mar 2021

Novel bioinformatics tool could help improve COVID-19 diagnosis

An interesting new study by researchers at the University of Liverpool, University of Bristol and Public Health England in the UK describes a novel bioinformatics tool used to detect subgenomic messenger ribonucleic acid (mRNA) sequences from the virus. This may help develop new diagnostic tools and model the transmission of the virus.

8 Mar 2021

FDA authorizes first molecular non-prescription, at-home COVID-19 test

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the Cue COVID-19 Test for Home and Over The Counter (OTC) Use.

5 Mar 2021

Identification of neutralizing IFNL3 autoantibodies in severe COVID-19 cases

Scientists have recently developed a novel alternative molecular display technology called Molecular Indexing of Proteins by Self Assembly (MIPSA). Their research explains how this technology overcomes the critical disadvantages of PLATO and other full-length protein array technologies.

5 Mar 2021

Researchers assess SARS-CoV-2 surface contamination risks in hospital setting

Researchers analyzed the surface swabs for SARS-CoV-2 RNA and the infectivity in a hospital setting by both qRT-PCR and a viral culture assay. They also determined the suitability for sequence analysis and phylogenetically identifying the source of the virus.

1 Mar 2021

New rapid diagnostic tests can differentiate between COVID-19 variants and multiple viruses

University of Minnesota Medical School researchers have developed two new rapid diagnostic tests for COVID-19 - one to detect COVID-19 variants and one to help differentiate with other illnesses that have COVID-19-like symptoms.

23 Feb 2021

After billions of dollars and dozens of wartime declarations, why are vaccines still in short supply?

The U.S. government has invested billions of dollars in manufacturing, used a wartime act dozens of times to boost supplies and yet there's still not enough covid vaccine on the way to meet demand — or even the government's own goals for national immunization.

23 Feb 2021

What makes viruses infectious?

In this interview, News-Medical spoke to Professor Peter Stockley about his latest research that looked at what makes viruses infectious.

23 Feb 2021

An overview of spike protein antigen COVID-19 vaccine candidates

A new paper in the journal Reviews in Medical Virology provides a perspective on current vaccine development strategies and tools, which may allow the production of safe and effective vaccines.

22 Feb 2021

SARS-CoV-2 was in NYC a good month before it was first identified, say researchers

Researchers at Icahn School of Medicine at Mount Sinai in New York have provided evidence suggesting that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – was infecting people in New York City (NYC) at least one month before the first case was officially documented in the city.

14 Feb 2021

Nucleic Acid News and Research

Delays in TB diagnosis often exceed WHO’s recommendations, shows study

New guidelines outline key new actions to improve delivery of HIV testing, treatment and care

Researchers explore nanotechnology’s potential to deliver synergistic therapeutics for COVID-19

Identifying druggable targets on an essential SARS-CoV-2 protein

Aptamer Group and Mologic enter commercial partnership to develop aptamer-based SARS-CoV-2 rapid antigen test

INTEGRA’s pipetting robot supports PCR-based HPV screening across France

The role of RNA capping of SARS-CoV-2 in immunity evasion

Promega launches XpressAmp™ Direct Amplification Reagents

QCMD to use RNAssist’s virusPHIX-P9™ Biomolecule Stabilization Technology in its SARS-CoV-2 antigen EQA scheme

Join a brief introduction to Nucleic Acid Gel Stains: exploring safer dyes and Non-UV imaging solutions

Apoptosis is an important mediator of pathogenesis in animal coronavirus infection

Novel bioinformatics tool could help improve COVID-19 diagnosis

FDA authorizes first molecular non-prescription, at-home COVID-19 test

Identification of neutralizing IFNL3 autoantibodies in severe COVID-19 cases

Researchers assess SARS-CoV-2 surface contamination risks in hospital setting

New rapid diagnostic tests can differentiate between COVID-19 variants and multiple viruses

After billions of dollars and dozens of wartime declarations, why are vaccines still in short supply?

What makes viruses infectious?

An overview of spike protein antigen COVID-19 vaccine candidates

SARS-CoV-2 was in NYC a good month before it was first identified, say researchers

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