Clinical Trial News and Research

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IU School of Medicine wins $12.3 million grant for research into opioid addiction treatment

Researchers at Indiana University School of Medicine are testing use of tezampanel, a novel antagonist at glutamate receptors that could treat opioid withdrawal syndrome and other addictions and mental illnesses.

17 Sep 2020

UC Davis uses microneedles to deliver gene therapy for retinal diseases

A novel approach to delivering gene therapy for retinal diseases eliminates the need for complex eye surgery and treats more damaged cells than existing methods, a team of UC Davis physicians and veterinary eye specialists has found.

16 Sep 2020

First clinical trial launched to test psilocybin therapy for depression in cancer patients

The first clinical trial to test the safety and feasibility of psilocybin therapy with simultaneous administration and one-on-one patient support to treat depression in cancer patients was launched today by Maryland Oncology Hematology at the Aquilino Cancer Center at Adventist HealthCare Shady Grove Medical Center.

16 Sep 2020

NTU-incubated start-up plans clinical trial of new slow-release pill for Parkinson’s disease

Materials scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed a new pill which uses the stomach as a drug reservoir and delivers medicines slowly over time to patients with Parkinson's disease (PD).

16 Sep 2020

COVID vaccine trials move at warp speed, but recruiting Black volunteers takes time

Participation in clinical trials among Black people is low, according to Food and Drug Administration statistics.

16 Sep 2020

Researchers are testing the effectiveness of multiple treatments to prevent COVID-19

A study on the effectiveness of multiple treatments, including laboratory-made antibodies, at preventing mild COVID-19 from advancing to severe illness in the outpatient setting is underway by researchers at The University of Texas Health Science Center at Houston (UTHealth).

16 Sep 2020

Can amodiaquine short circuit this pandemic?

A recent study by the US researchers highlights the value of the human organ chip technology as a more robust and physiologically relevant platform for rapid drug repurposing, and suggest that amodiaquine may be used to prevent the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Sep 2020

Study reveals damaging role of immune system in severe brain infection

A new study has detailed the damaging role played by the immune system in a severe brain condition most commonly caused by the cold sore virus.

15 Sep 2020

New biomarker can reliably predict aggressiveness of biliary tract cancer

The cancer called biliary tract cancer (BTC) is not the most widespread form of cancer. In western countries, about 1.6 in 100.000 gets the diagnose every year. It is, however, a very aggressive form of cancer.

15 Sep 2020

Study uncovers a promising new therapeutic approach for Duchenne muscular dystrophy

Scientists at Sanford Burnham Prebys Medical Discovery Institute, Fondazione Santa Lucia IRCCS, and Università Cattolica del Sacro Cuore in Rome have shown that pharmacological (drug) correction of the content of extracellular vesicles released within dystrophic muscles can restore their ability to regenerate muscle and prevent muscle scarring (fibrosis).

15 Sep 2020

New clinical trial shows combination of two innovative precision medicines could treat multiple cancers

Launching a dual-pronged attack on tumours using a combination of two innovative precision medicines could treat patients with multiple common cancers, a new clinical trial shows.

15 Sep 2020

LRRK2 enzyme suppresses protein synthesis in Parkinson’s disease

In a recently published study, researchers from the Turku Bioscience Centre at the University of Turku and Åbo Akademi University in Finland monitored the production of new proteins as they were produced by the cells' protein building machinery, the ribosome.

15 Sep 2020

Identifying, preventing and treating drug-induced arrhythmias

Health care professionals should become more familiar with medications that cause irregular heart rhythms called arrhythmias, according to "Drug- Induced Arrhythmias," a new scientific statement from the American Heart Association, published today in the Association's flagship journal Circulation.

15 Sep 2020

Higher doses of Botox may lead to bone loss, shows study

Botox injections to manage jaw and facial pain do not result in clinically significant changes in jaw bone when used short term and in low doses, according to researchers at NYU College of Dentistry.

15 Sep 2020

Oxford University and AstraZeneca resume COVID-19 vaccine trial

More than a hundred candidate vaccine trials against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19), are underway. About 35 are now undergoing clinical evaluation, and of these, nine are in the final phase of human trials, including the vaccine developed by Oxford University and the biopharmaceutical firm, AstraZeneca.

14 Sep 2020

Phosphate binder drug does not reduce heart disease risk in people with chronic kidney disease

Following a large-scale clinical trial, researchers have found that lanthanum carbonate does not reduce the risk of cardiovascular disease developing in patients with chronic kidney disease.

14 Sep 2020

COVID-19 pandemic affects delivery of cancer care and oncologists' wellbeing

Delays and cancellation of cancer treatments and other safety measures undertaken to minimise the risk of exposure to the coronavirus (COVID-19) have generated a huge backlog in oncology care and research.

14 Sep 2020

Supplements of Human Milk Oligosaccharides may help improve gut health in adults

Supplements of Human Milk Oligosaccharides (HMOs), the sugars found in breast milk, may help improve the gut health of adults, according to new research carried out at the Quadram Institute.

14 Sep 2020

Electroconvulsive therapy can reduce suicide risk by 84% in bipolar patients

One of the largest ever studies of patients with untreatable bipolar disorder has shown that ECT (Electroconvulsive Therapy) was able to reduce suicide risk by 84% in high-risk patients, as well as giving effective treatment to around 72% of sufferers.

12 Sep 2020

Simple blood tests can benefit women with breast cancer

A blood test that can identify a variety of mutations in advanced breast cancer can reliably match women to effective targeted treatments, early results of a major clinical trial reveal.

11 Sep 2020

Clinical Trial News and Research

IU School of Medicine wins $12.3 million grant for research into opioid addiction treatment

UC Davis uses microneedles to deliver gene therapy for retinal diseases

First clinical trial launched to test psilocybin therapy for depression in cancer patients

NTU-incubated start-up plans clinical trial of new slow-release pill for Parkinson’s disease

COVID vaccine trials move at warp speed, but recruiting Black volunteers takes time

Researchers are testing the effectiveness of multiple treatments to prevent COVID-19

Can amodiaquine short circuit this pandemic?

Study reveals damaging role of immune system in severe brain infection

New biomarker can reliably predict aggressiveness of biliary tract cancer

Study uncovers a promising new therapeutic approach for Duchenne muscular dystrophy

New clinical trial shows combination of two innovative precision medicines could treat multiple cancers

LRRK2 enzyme suppresses protein synthesis in Parkinson’s disease

Identifying, preventing and treating drug-induced arrhythmias

Higher doses of Botox may lead to bone loss, shows study

Oxford University and AstraZeneca resume COVID-19 vaccine trial

Phosphate binder drug does not reduce heart disease risk in people with chronic kidney disease

COVID-19 pandemic affects delivery of cancer care and oncologists' wellbeing

Supplements of Human Milk Oligosaccharides may help improve gut health in adults

Electroconvulsive therapy can reduce suicide risk by 84% in bipolar patients

Simple blood tests can benefit women with breast cancer

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