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New mice study unveils mystery of why chronic stress, depression can lead to bone loss

A new study has helped to unveil the mystery of why chronic stress and depression can lead to bone loss and increase the risk of fractures.

19 May 2016

Hydroxyurea treatment improves pulmonary function decline in children with sickle cell disease

For the first time, researchers were able to demonstrate that children diagnosed with sickle cell disease showed improvement in lung function after treatment with hydroxyurea, a treatment that is underused despite its demonstrated benefits.

19 May 2016

Mazor Robotics signs strategic commercial and investment agreements with Medtronic

Mazor Robotics Ltd., a leading developer of innovative bone mounted surgical robotic guidance systems, today entered into two strategic agreements with Medtronic plc (NYSE: MDT). One agreement is a two-stage, multi-faceted, commercial agreement for co-promotion, co-development and, upon meeting certain milestones, potential global distribution of certain Mazor products. The second agreement is for an equity investment by Medtronic in Mazor.

19 May 2016

$Allogeneic HSCT offers good survival for select TKI-refractory CML patients$

Allogeneic HSCT offers good survival for select TKI-refractory CML patients

Allogeneic hematopoietic stem cell transplantation is associated with a high rate of survival for carefully chosen chronic myeloid leukaemia patients who do not respond well to tyrosine kinase inhibitor therapy, research suggests.

18 May 2016

New bio-mimicry method allows scientists to track cells in vivo using MRI during preclinical, clinical trials

Researchers led by Carnegie Mellon University Professor of Biological Sciences Chien Ho have developed a new method for preparing mesenchymal stem cells (MSCs) that not only leads to the production of more native stem cells, but also labels them with a FDA approved iron-oxide nanoparticle (Ferumoxytol).

18 May 2016

Low levels of vitamin D in Orkney may explain reason for higher rates of multiple sclerosis

Holidays abroad may hold the key to tackling Scotland's vitamin D deficiency, research suggests.

18 May 2016

Research shows close similarities of canine models of human rare disorders

Professor Hannes Lohi's research group at the University of Helsinki has discovered three novel canine genes for Caffey, Raine and van den Ende-Gupta syndromes. Research reveals close similarities of the canine models of human rare disorders and highlights the potential of comparative research approach for the development of rare disease diagnostics and treatments.

18 May 2016

Suture anchor technique supports more knee movement during recovery process

Quadriceps tendon ruptures are disabling knee injuries that typically occur in adults ages 40 and older. Obesity, illness or traumatic injuries can cause these types of injuries.

17 May 2016

Phase 2 results of AbbVie’s venetoclax in patients with R/R CLL with 17p deletion published in The Lancet Oncology

AbbVie, a global biopharmaceutical company, today announced The Lancet Oncology published results from the Phase 2, single arm, open label trial studying venetoclax in patients with relapsed/refractory (R/R) chronic lymphocytic leukaemia (CLL) with 17p deletion.

17 May 2016

University of Colorado Boulder combines Raman spectroscopy and nanoindentation for improved materials characterisation

The University of Colorado Boulder, USA, combines Raman spectroscopy and nanoindentation for improved materials characterisation.

From Renishaw plc - Spectroscopy 16 May 2016

Arkin Holdings and Primera Capital lead investment of $13M in BioSight

BioSight, Ltd, an Israeli pharmaceutical development company focused on the development of innovative chemotherapy pro-drugs with reduced toxicity, announced today the closing of an investment of $13M led by the Mori Arkin's pharmaceutical investment firm, Arkin Holdings, and the US based venture firm Primera Capital. Proceeds of the financing will be used to fund a multi-center phase IIb clinical trial with the company's lead product, Astarabine™, for the treatment of AML.

16 May 2016

Inhibiting autophagy can effectively block tumor cell migration, breast cancer metastasis

Researchers from the University of Chicago have shown that inhibiting autophagy, a self-devouring process used by cells to degrade large intra-cellular cargo, effectively blocks tumor cell migration and breast cancer metastasis in tumor models.

13 May 2016

Genetic change to non-DNA structures in cell can cause cancer

A mutation that affects the proteins that package DNA--without changing the DNA itself--can cause a rare form of cancer, according to new findings in this week's Science from researchers at The Rockefeller University.

13 May 2016

Histone mutation linked to fatal pediatric brain tumor

A single defect in a gene that codes for a histone — a "spool" that wraps idle DNA — is linked to pediatric cancers in a study published today in the journal Science.

13 May 2016

Vessel-sparing radiation, better understanding of prostate anatomy can improve quality of life

Remember the game Operation? You need to carefully remove the body part without nicking the sides or the buzzer will sound.

12 May 2016

Stimulating stem cells to make special type of cartilage may potentially heal broken bones

Stem cells could one day be stimulated to make a special type of cartilage to help repair large, hard-to-heal bone fractures - a potential boon for doctors treating big-money athletes, USC researchers say.

12 May 2016

Novel UBC-developed device could soon pave way for improved cancer diagnosis

A new UBC-developed method to isolate cancer cells that have escaped from a tumour could soon pave the way for improved diagnosis and treatment.

12 May 2016

Benefits of calcium supplements in preventing broken bones may be cancelled out by increased stroke risk

Taking calcium and vitamin D can help prevent broken bones in older women. However, this benefit may be cancelled out by an increased risk of heart attack and stroke.

12 May 2016

Visiting consultant clinics improve access to orthopaedic care in rural areas

Patients living in rural areas are more likely to be older, overweight and less physically active--all risk factors for orthopaedic conditions. And yet, with few orthopaedic surgeons practicing in rural areas, access to care is limited.

12 May 2016

Researchers agree to test new stem cell gene therapy for Sanfilippo disease in human trial

Scientists in Manchester, who have developed a stem cell gene therapy to reverse a fatal childhood illness, have agreed to work with a new therapeutics company to test it in a human trial.

11 May 2016

Bone News and Research

New mice study unveils mystery of why chronic stress, depression can lead to bone loss

Hydroxyurea treatment improves pulmonary function decline in children with sickle cell disease

Mazor Robotics signs strategic commercial and investment agreements with Medtronic

Allogeneic HSCT offers good survival for select TKI-refractory CML patients

New bio-mimicry method allows scientists to track cells in vivo using MRI during preclinical, clinical trials

Low levels of vitamin D in Orkney may explain reason for higher rates of multiple sclerosis

Research shows close similarities of canine models of human rare disorders

Suture anchor technique supports more knee movement during recovery process

Phase 2 results of AbbVie’s venetoclax in patients with R/R CLL with 17p deletion published in The Lancet Oncology

University of Colorado Boulder combines Raman spectroscopy and nanoindentation for improved materials characterisation

Arkin Holdings and Primera Capital lead investment of $13M in BioSight

Inhibiting autophagy can effectively block tumor cell migration, breast cancer metastasis

Genetic change to non-DNA structures in cell can cause cancer

Histone mutation linked to fatal pediatric brain tumor

Vessel-sparing radiation, better understanding of prostate anatomy can improve quality of life

Stimulating stem cells to make special type of cartilage may potentially heal broken bones

Novel UBC-developed device could soon pave way for improved cancer diagnosis

Benefits of calcium supplements in preventing broken bones may be cancelled out by increased stroke risk

Visiting consultant clinics improve access to orthopaedic care in rural areas

Researchers agree to test new stem cell gene therapy for Sanfilippo disease in human trial

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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