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Understanding immune drift in biologic therapy for inflammatory skin diseases

Immune-inflammatory skin diseases (e.g., psoriasis, atopic dermatitis) involve dysregulation of CD4+ T-cell subsets (Th1/Th2/Th17/Treg) and cytokine networks (IL-17/IL-23/IL-4).

28 Jul 2025

AI-powered blood test improves early Lyme disease detection

Today at ADLM 2025 (formerly the AACC Annual Scientific Meeting & Clinical Lab Expo), researchers will unveil a blood test developed with the help of artificial intelligence (AI) that identifies Lyme disease sooner and more accurately than the current standard - and that could translate to vastly improved patient outcomes.

28 Jul 2025

Restoring mitochondria enhances immune response against lung cancer

While chemotherapy remains a cornerstone of lung cancer treatment, it often weakens the immune system it relies on for long-term control.

28 Jul 2025

New software predicts cancer cell behavior to advance treatment

In the same vein as weather forecast models that predict developing storms, researchers now have developed a method to predict the cell activity in tissues over time.

28 Jul 2025

Metabolic rewiring turns immune cells into potent cancer fighters

Researchers have discovered a way to make the immune system's T cells significantly more effective at fighting cancer.

28 Jul 2025

Vitamin D supplementation reduces liver inflammation and fibrosis largely through TXNIP

Chronic liver disease (CLD) is a major global health concern, affecting approximately 1.5 billion people. This life-threatening disease often progresses silently, eventually leading to worsened conditions like liver cirrhosis or liver cancer.

28 Jul 2025

Marbling of fat inside muscles found to block healing and weaken strength

Consider the delicate web of fat in a Wagyu steak. The "marbling" that makes carnivore connoisseurs swoon is a visual heuristic for quality flavor.

28 Jul 2025

Advancing precision medicine in colorectal cancer with multi-omics approaches

Colorectal cancer is among the most prevalent and lethal malignancies worldwide, with liver metastases occurring in nearly one-third of patients and accounting for a major share of cancer-related deaths.

28 Jul 2025

Neutrophils emerge as key players in cancer progression and therapy

Neutrophils are the most abundant type of white blood cells, critical for immune defense and inflammation control.

28 Jul 2025

American Heart Association expands Cardiovascular-Kidney-Metabolic Health Initiative to 15 regions

People in 15 regions across the U.S. will soon benefit from the American Heart Association's Cardiovascular-Kidney-Metabolic Health Initiative™, designed to improve treatment of the interconnected conditions that lead to heart disease and stroke.

28 Jul 2025

Cardiologists urged to prioritize potent statins in managing LDL cholesterol

There is broad consensus that the overall body of evidence shows lowering LDL (low-density lipoprotein) cholesterol provides both statistically significant and clinically meaningful benefits in treating and preventing cardiovascular disease.

28 Jul 2025

Study: Formal education does not slow brain aging or cognitive decline

An international study published in the journal Nature Medicine casts doubt on the widespread belief that higher levels of formal education directly protect against cognitive decline and brain aging.

28 Jul 2025

More Diagnostics announces the launch of two advanced cardiac-focused products

More Diagnostics, a trusted leader in in vitro diagnostic quality controls for over 30 years, is proud to announce the debut of two advanced cardiac-focused products: a High-Sensitivity Troponin Control and a Clinical Cardiac Control.

28 Jul 2025

Columbia engineers create bioactive hydrogels using dairy-derived EVs

Researchers from Columbia Engineering have established a framework for the design of bioactive injectable hydrogels formulated with extracellular vesicles (EVs) for tissue engineering and regenerative medicine applications.

28 Jul 2025

Largest genetic study confirms biological basis of stuttering

The largest genetic analysis of stuttering has demonstrated a clear genetic basis for the speech disorder, highlighting neurological pathways of risk.

28 Jul 2025

Study reveals a strong link between early childhood adversities and depression in older Canadians

A new study of 3,500 Canadians aged 55 and older revealed a strong association between early childhood adversities and depression.

28 Jul 2025

Promising new male birth control pill could be taken every three days

YCT-529, a novel non-hormonal male contraceptive, demonstrates safety and tolerability in early trials, offering a potential solution for male birth control.

28 Jul 2025

Cosmetic surgeries led to disfiguring injuries, patients allege

A few days after a harrowing cosmetic surgery procedure, Erin Schaeffer said, she woke up with fluid leaking from an open wound in her stomach.

28 Jul 2025

Researchers map atomic structure of protein complex driving cilia movement

A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the surfaces of many cell types that generate their movement.

28 Jul 2025

UCSF discovery points to new strategies for Alzheimer's treatment

UCSF scientists have discovered how microglia engulf and break down amyloid beta, a protein that builds up in Alzheimer's, with devastating consequences for the brain.

28 Jul 2025