immunity News and Research

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Study suggests vast majority of Seattle population remains susceptible to COVID-19

Researchers in the United States have conducted a study suggesting that a small proportion of people living in Seattle were infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – by around late March/early April 2020.

9 Dec 2020

Different SARS-CoV-2 neutralization assays are reliable and concordant for antibody monitoring

A recent study by US researchers, currently available on the medRxiv preprint server, evaluated several cell-based assays that are under validation for determining correlates of protection in individuals with symptomatic coronavirus disease (COVID-19) and vaccine studies – and demonstrated their high concordance with both live and pseudotyped virions.

9 Dec 2020

Considerable COVID-19 vaccination hesitancy in UK may affect herd immunity, study finds

Scientists from the Imperial College London and the Imperial College Healthcare NHS Trust, UK, have conducted a cross-sectional, questionnaire-based survey to evaluate the public’s willingness to receive coronavirus disease 2019 (COVID-19) vaccination and their attitude toward prioritization.

9 Dec 2020

Interim results show Oxford COVID-19 vaccine protects against symptomatic disease

First full results from interim analysis confirm that the Oxford COVID-19 vaccine (AZD1222) has an acceptable safety profile and is efficacious against symptomatic COVID-19 disease, with no hospitalizations or severe disease reported in the COVID-19 vaccine group so far.

9 Dec 2020

Researchers compare data from blood donors to infer the attack rate of SARS-CoV-2 virus

Researchers studying data from blood donors in Manaus, Brazil, who experienced high mortality from SARS-CoV-2, estimate that more than 70% of the population was infected approximately seven months after the virus first arrived in the city.

9 Dec 2020

UC Davis Health joins with Novavax to test a new experimental coronavirus vaccine

Despite the encouraging news of potentially successful COVID-19 vaccine trials, there is not yet an FDA-approved vaccine available. Research into other effective coronavirus vaccines continues, including at UC Davis Health.

8 Dec 2020

High-performing multi-immunoassay for early diagnosis and prognosis of COVID-19

A new study published on the preprint server bioRxiv in December 2020 indicates the ability of anti-SARS-CoV-2 antibody titers and time of induction to differentiate between severe and mild COVID-19 and could lead to the development of a prognostic biomarker for use early in the course of the illness.

8 Dec 2020

Why is COVID-19 more severe among adults than children?

Researchers in Switzerland and Australia have reviewed some of the mechanisms proposed regarding why coronavirus disease 2019 (COVID-19) is generally less severe among children than among adults.

8 Dec 2020

Tension between awareness and fatigue can shift the shape of coronavirus pandemic

In the midst of the coronavirus pandemic, two human factors are battling it out: awareness of the virus's severe consequences and fatigue from nine months of pandemic precautions.

8 Dec 2020

Lipid storm in severe COVID-19 linked to high COX/LOX pathway activity

A potentially valuable new study discusses the role of lipids in the hyper-inflammatory phenomena that take place within the lungs of patients with severe or critical COVID-19. Involving a large variety of specialized lipids with biological activity, this process includes the generation and release of pro and anti-inflammatory lipids.

8 Dec 2020

Oligourea-based "fake" peptides enhance options for rational drug design, shows study

Some useful drugs consist of peptides acting on their protein targets. To make them more efficient and stable, scientists have found a way to replace crucial segments of the peptides with ureido units.

8 Dec 2020

Mount Sinai study shows strong immune response, durability of universal influenza virus vaccine

A vaccine that induces immune responses to a wide spectrum of influenza virus strains and subtypes has produced strong and durable results in early-stage clinical trials in humans, Mount Sinai researchers have found.

7 Dec 2020

No evidence for risk of vaccine-driven virulence evolution in SARS-CoV-2

Beyond the morbidity and mortality associated with the pandemic, COVID-19 has paralyzed the global economy.

7 Dec 2020

Failure to comply with COVID-19 containment measures penalizes the compliant as well

The COVID-19 pandemic is now in its second wave and deaths are surpassing the spring peak as winter sets in over much of the northern hemisphere.

7 Dec 2020

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Clinical investigators from Hackensack Meridian Health John Theurer Cancer Center (JTCC), a member of the Georgetown Lombardi Comprehensive Cancer Center consortium, are to present updates on treatment advances in multiple myeloma (MM), mantle cell lymphoma (MCL), and other types of B-cell lymphoma (BCL) as well as leukemia at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, to be held virtually from December 5-8, 2020.

7 Dec 2020

Immunity passports may be valid based on how they are used, says UPV/EHU expert

According to the Chair in Law and the Human Genome at the University of the Basque Country (UPV/EHU), immunity passports may be valid, depending on how they are used.

6 Dec 2020

Researchers shed light on the role of antibodies and immune cells in protection against COVID-19

Since the novel coronavirus emerged at the end of last year, scientists around the world -- including Beth Israel Deaconess Medical Center (BIDMC) immunologist Dan Barouch, MD, PhD -- have been developing vaccines to protect against COVID-19 and to put an end to the global pandemic.

5 Dec 2020

COVID-19 herd immunity threshold far higher than previously thought, say researchers

Researchers in the US have re-analyzed the data on herd immunity from spring 2020 from Europe. Their study shows that the herd immunity threshold is much higher than earlier speculated.

4 Dec 2020

Study offers hope to parents and kids who face real danger from peanut exposure

It's a peanut-filled world--or at least it can feel that way for kids with peanut allergies. But a new study by researchers at the University of British Columbia and BC Children's Hospital gives hope to parents and kids who face real danger from exposure to peanuts.

3 Dec 2020

Vaccination against tuberculosis has influence on the epidemiology of COVID-19

St Petersburg University scientists have analyzed about 100 academic papers and statistics on the incidence of COVID-19 in different countries of the world.

3 Dec 2020

immunity News and Research

Study suggests vast majority of Seattle population remains susceptible to COVID-19

Different SARS-CoV-2 neutralization assays are reliable and concordant for antibody monitoring

Considerable COVID-19 vaccination hesitancy in UK may affect herd immunity, study finds

Interim results show Oxford COVID-19 vaccine protects against symptomatic disease

Researchers compare data from blood donors to infer the attack rate of SARS-CoV-2 virus

UC Davis Health joins with Novavax to test a new experimental coronavirus vaccine

High-performing multi-immunoassay for early diagnosis and prognosis of COVID-19

Why is COVID-19 more severe among adults than children?

Tension between awareness and fatigue can shift the shape of coronavirus pandemic

Lipid storm in severe COVID-19 linked to high COX/LOX pathway activity

Oligourea-based "fake" peptides enhance options for rational drug design, shows study

Mount Sinai study shows strong immune response, durability of universal influenza virus vaccine

No evidence for risk of vaccine-driven virulence evolution in SARS-CoV-2

Failure to comply with COVID-19 containment measures penalizes the compliant as well

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Immunity passports may be valid based on how they are used, says UPV/EHU expert

Researchers shed light on the role of antibodies and immune cells in protection against COVID-19

COVID-19 herd immunity threshold far higher than previously thought, say researchers

Study offers hope to parents and kids who face real danger from peanut exposure

Vaccination against tuberculosis has influence on the epidemiology of COVID-19

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