Clinical Trial News and Research

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FDA approves a hybrid closed loop diabetes management device for young pediatric patients

Today, the U.S. Food and Drug Administration approved the MiniMed 770G System, a hybrid closed loop diabetes management device that is intended to automatically monitor glucose (sugar) and provide appropriate basal insulin doses with little or no input from the users or their caregivers for use by individuals aged 2 to 6 with type 1 diabetes.

31 Aug 2020

Triple therapy increases response rates in patients with Severe Aplastic Anemia

The European Society for Blood and Marrow Transplantation (EBMT), Europe's collaborative peer network of professionals working in the field of stem cell transplantation and cellular therapy, announced today the results of the phase III RACE trial during EBMTs virtual 46th Annual Meeting. Preliminary data show that adding Eltrombopag to standard immunosuppressive treatment is safe and increases response rates in patients with Severe Aplastic Anaemia.

31 Aug 2020

Study: Mavacamten improves heart function in patients with hypertrophic cardiomyopathy

Mavacamten improves heart function and symptoms in patients with obstructive hypertrophic cardiomyopathy, according to results of the EXPLORER-HCM trial presented in a Hot Line session today at ESC Congress 2020.

31 Aug 2020

Race to produce COVID vaccines should not leave the poor left behind, says expert

Race to produce vaccines against COVID-19 must ensure that the poor are not left behind, says Crispin Maslog. A mad race to produce a vaccine against COVID-19 has begun with the world's superpowers leading the pack.

29 Aug 2020

Study shows benefits of new palliative care model for patients with neurological conditions

Findings from a large-scale clinical trial testing a new palliative care model have shown to be lower cost, viewed positively by patients and their carers while showing no difference in patient-reported outcomes when compared with standard care.

28 Aug 2020

New brain study may lead to optimal treatment for obsessive-compulsive disorder

New research could improve the odds that people with obsessive-compulsive disorder will receive a therapy that really works for them - something that eludes more than a third of those who currently get OCD treatment.

28 Aug 2020

New breast cancer drug is safe and effective, can halt disease progression

A new type of breast cancer drug developed by researchers at the University of Illinois Chicago can help halt progression of disease and is not toxic, according to phase 1 clinical trials. The drug is specifically designed for women whose cancer has stopped responding to hormone therapy.

28 Aug 2020

Blood thinners help reduce the risk of COVID-19 deaths, study finds

Now, a new study by a team of researchers at the Mount Sinai Health System in New York has shown that blood thinners may reduce the risk of death by up to 50 percent among severely ill hospitalized COVID-19 patients.

27 Aug 2020

Mouse-adapted SARS-CoV-2 model helps advance the development of COVID-19 vaccines

A new COVID-19 mouse model developed at the University of North Carolina at Chapel Hill captures many of the features of human disease and has helped advance a COVID-19 vaccine candidate to clinical trial.

27 Aug 2020

5 things to know about convalescent blood plasma

President Donald Trump told the American people this week that convalescent plasma is a potential new treatment for COVID-19.

27 Aug 2020

New diagnostic tool can predict cancer patients' response to immunotherapy

A new diagnostic tool that can predict whether a cancer patient would respond to immunotherapy treatment has been developed by scientists at the University of Bath.

27 Aug 2020

Artificial pancreas manages blood sugar levels in type 1 diabetes children

An artificial pancreas originally developed at the University of Virginia Center for Diabetes Technology safely and effectively manages blood sugar levels in children ages 6 to 13 with type 1 diabetes, a national clinical trial has found.

27 Aug 2020

Anticoagulation therapy associated with improved survival among COVID-19 patients

Early in the COVID-19 pandemic, Mount Sinai researchers were among the first to show that anticoagulation therapy was associated with improved survival among hospitalized COVID-19 patients

27 Aug 2020

UKRI funding could initiate clinical trial for Cambridge-developed DNA vaccine against SARS-CoV-2

A Cambridge-developed DNA vaccine candidate against SARS-CoV-2 could begin clinical trials in the UK in late autumn or early next year, thanks to a £1.9 million award from the UK government.

27 Aug 2020

Heat Biologics SARS-CoV-2 vaccine generates potent T cell response in pre-clinical trial

The COVID-19 pandemic is still creating economic and health-related impact over the world. A new study published on the preprint server bioRxiv in August 2020 shows that a gp96-Ig-secreting vaccine candidate based on the expression of full-length spike protein generates a potent T cell response.

26 Aug 2020

Consuming personal fecal microbiome when dieting may limit weight regain, study shows

People who consume frozen microbiome capsules derived from their own feces when dieting may limit their weight regain, according to a new study published in Gastroenterology, conducted by a team of researchers led by researchers at Ben-Gurion University of the Negev.

26 Aug 2020

Inhaled steroid ciclesonide suppresses SARS-CoV-2 replication in vitro

A new paper by researchers at Japan’s National Institute of Infectious Diseases and published on the preprint server bioRxiv in August 2020 reports the in vitro suppression of coronavirus (CoV) replication by an inhaled corticosteroid (ICS) ciclesonide.

26 Aug 2020

Vitamin D supplements do not prevent severe asthma attacks in children

Contrary to earlier results, vitamin D supplements do not prevent severe asthma attacks in at-risk children, according to the first placebo-controlled clinical trial to test this relationship.

25 Aug 2020

Preclinical studies of a COVID-19 vaccine candidate show positive results

Preclinical studies of a COVID-19 vaccine candidate at the University of Alabama at Birmingham show positive results that appear to distinguish this vaccine candidate from other vaccine candidates that are currently in advanced stages of clinical development, the Maryland-based Altimmune Inc. announced today.

25 Aug 2020

UVA-designed nasopharyngeal swabs to support high-priority COVID-19 testing across Virginia

The Commonwealth of Virginia will receive 60,000 nasopharyngeal swabs weekly to support high-priority COVID-19 testing across the state, thanks to a collaboration led by University of Virginia faculty to design this key testing supply.

25 Aug 2020

Clinical Trial News and Research

FDA approves a hybrid closed loop diabetes management device for young pediatric patients

Triple therapy increases response rates in patients with Severe Aplastic Anemia

Study: Mavacamten improves heart function in patients with hypertrophic cardiomyopathy

Race to produce COVID vaccines should not leave the poor left behind, says expert

Study shows benefits of new palliative care model for patients with neurological conditions

New brain study may lead to optimal treatment for obsessive-compulsive disorder

New breast cancer drug is safe and effective, can halt disease progression

Blood thinners help reduce the risk of COVID-19 deaths, study finds

Mouse-adapted SARS-CoV-2 model helps advance the development of COVID-19 vaccines

5 things to know about convalescent blood plasma

New diagnostic tool can predict cancer patients' response to immunotherapy

Artificial pancreas manages blood sugar levels in type 1 diabetes children

Anticoagulation therapy associated with improved survival among COVID-19 patients

UKRI funding could initiate clinical trial for Cambridge-developed DNA vaccine against SARS-CoV-2

Heat Biologics SARS-CoV-2 vaccine generates potent T cell response in pre-clinical trial

Consuming personal fecal microbiome when dieting may limit weight regain, study shows

Inhaled steroid ciclesonide suppresses SARS-CoV-2 replication in vitro

Vitamin D supplements do not prevent severe asthma attacks in children

Preclinical studies of a COVID-19 vaccine candidate show positive results

UVA-designed nasopharyngeal swabs to support high-priority COVID-19 testing across Virginia

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