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New discovery may offer a promising avenue for study of multiple sclerosis

A surprising discovery may offer a promising new direction in the study of multiple sclerosis and other diseases of hypomyelination – when axons of neurons are not covered sufficiently in fatty sheaths (myelin), which disrupts communication between nerve cells.

23 Sep 2021

People with natural immunity and subsequent mRNA vaccination can neutralize viral particles capable of resisting vaccine-induced antibodies

New research suggests SARS-CoV-2 spike protein substitution mutations can create a replication-defective viral particle that makes the virus resistant to vaccine-induced antibodies.

23 Sep 2021

Varying immune responses after single dose of Pfizer and AstraZeneca COVID-19 vaccines

A new preprint describes the significant variation in the early immune response elicited by two of the earliest vaccines to gain emergency authorization against COVID-19.

23 Sep 2021

Long-term effects of COVID-19 in children

A recent preprint deals with the incidence and importance of long COVID in children.

23 Sep 2021

The impact of multiple sclerosis therapy on COVID-19 vaccine efficacy

In a paper, the vaccine-induced cellular and immune response of MS patients receiving a range of therapies are assessed.

23 Sep 2021

Antibody kinetics in recovered COVID-19 patients

Researchers from Tel Aviv University have been examining the kinetics of antibodies in recovered COVID-19 patients.

23 Sep 2021

Scientists reveal the biological process leading to dangerous inflammatory disease in preemies

In a study with mice reported today in the journal Science Translational Medicine, a Johns Hopkins Medicine research team has provided what may be the most definitive view to date of the biological process leading to necrotizing enterocolitis (NEC), a dangerous inflammatory disease that can destroy a premature infant's intestinal lining and causes death in up to a third of the cases.

23 Sep 2021

McLean wins NIH grant to explore links between COVID-19 vaccine and menstrual cycle changes

In research that will add important data to the experience of vaccines on women's health, Laura Payne, PhD, director of McLean Hospital's Clinical and Translational Pain Research Laboratory, has received a grant from the National Institutes of Health to explore potential links between SARS-CoV-2 vaccination and menstrual cycle changes.

23 Sep 2021

mRNA-based and adenoviral vector-based COVID-19 vaccines elicit diverse humoral immunity

Scientists from the USA have recently compared the dynamics of humoral and cellular immune responses induced by mRNA-based and adenoviral vector-based coronavirus disease 2019 (COVID-19) vaccines. The findings reveal a difference in humoral immune responses. The study is currently available on the medRxiv* preprint server.

22 Sep 2021

The importance of handwashing in the COVID-19 era: Back to basics

Researchers from the United States have reviewed the different components of formulated soaps and their performance as cleansers and pathogen inactivators, the criticality of the time spent hand washing, the relationships between water temperature and pathogen inactivation.

22 Sep 2021

Pinning down Pin1: Potential COVID-19 therapy

In a recent study scientists have demonstrated that Pin1 is one of the key cellular molecules necessary for SARS-CoV-2 propagation.

22 Sep 2021

Hypertonic saline solution shown to inhibit replication of SARS-CoV-2

Researchers at the University of São Paulo (USP) in Brazil have shown that a hypertonic saline solution inhibits replication of SARS-CoV-2, the virus that causes COVID-19, and have elucidated the biochemical mechanism involved.

22 Sep 2021

COVID-19 vaccination in IBD patients

In this review, researchers reviewed all published research related to Phase 1/2 and/or Phase 3 and 4 studies of SARS-CoV-2 vaccinations.

22 Sep 2021

Those undergoing treatment for hematological malignancies show reduced immune response to COVID-19 vaccines

Researchers recently investigated the effect of infection with SARS-CoV-2 in patients with hematologic malignancies in minority populations.

21 Sep 2021

Comparison of recombinant SARS-CoV-2 receptor binding domain produced in mammalian, insect, and bacterial cells

In a recent study, RBD produced in various cell types are characterized in-depth, comparing their applicability for future COVID-19 research.

21 Sep 2021

Researchers provide structural insights into HCV receptor binding and entry

In a new paper published in Nature, scientists from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, describe the structure of a key protein on the surface of the hepatitis C virus (HCV) and how it interacts with its receptor found on some human cells.

21 Sep 2021

Scientists identify potential therapeutic targets to alleviate severe COVID-19 in aged patients

The scientists assessed epidemiological data from March to December 2020 from the CDC to investigate the prevalence of COVID-19 disease among different age groups.

21 Sep 2021

Three US COVID-19 vaccines provide substantial protection against hospitalization

A new study reports that a head-to-head comparison of the efficacy of the three vaccines used in the USA indicates substantial protection against hospitalization with COVID-19 following vaccination with any of these vaccines.

21 Sep 2021

Breath measurements can be used to determine antibiotic concentrations in the body

A team of engineers and biotechnologists at the University of Freiburg has for the first time shown in mammals that the concentration of antibiotics in the body can be determined using breath samples. The breath measurements also corresponded to the antibiotic concentrations in the blood.

21 Sep 2021

New cell-free antibody generation platform successfully creates neutralizing antibodies effective against SARS-CoV-2

Researchers from the Broad Institute of MIT and Harvard have created a cell-free nanobody engineering platform that can produce antibodies effectively and quickly.

21 Sep 2021

Receptor News and Research

New discovery may offer a promising avenue for study of multiple sclerosis

People with natural immunity and subsequent mRNA vaccination can neutralize viral particles capable of resisting vaccine-induced antibodies

Varying immune responses after single dose of Pfizer and AstraZeneca COVID-19 vaccines

Long-term effects of COVID-19 in children

The impact of multiple sclerosis therapy on COVID-19 vaccine efficacy

Antibody kinetics in recovered COVID-19 patients

Scientists reveal the biological process leading to dangerous inflammatory disease in preemies

McLean wins NIH grant to explore links between COVID-19 vaccine and menstrual cycle changes

mRNA-based and adenoviral vector-based COVID-19 vaccines elicit diverse humoral immunity

The importance of handwashing in the COVID-19 era: Back to basics

Pinning down Pin1: Potential COVID-19 therapy

Hypertonic saline solution shown to inhibit replication of SARS-CoV-2

COVID-19 vaccination in IBD patients

Those undergoing treatment for hematological malignancies show reduced immune response to COVID-19 vaccines

Comparison of recombinant SARS-CoV-2 receptor binding domain produced in mammalian, insect, and bacterial cells

Researchers provide structural insights into HCV receptor binding and entry

Scientists identify potential therapeutic targets to alleviate severe COVID-19 in aged patients

Three US COVID-19 vaccines provide substantial protection against hospitalization

Breath measurements can be used to determine antibiotic concentrations in the body

New cell-free antibody generation platform successfully creates neutralizing antibodies effective against SARS-CoV-2

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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