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New genetic system analyzes the underlying mechanisms of CRISPR-based DNA repair outcomes

Since its breakthrough development more than a decade ago, CRISPR has revolutionized DNA editing across a broad range of fields.

26 Mar 2024

Antioxidant-rich diets linked to lower type 2 diabetes risk, supplements less effective

Study systematically reviews the impact of dietary antioxidants, vitamins C, E, and beta-carotene, on reducing the risk of type 2 diabetes, suggesting an inverse association with the disease, though no protective effects from supplementation were observed.

26 Mar 2024

Organ-on-a-chip technology revolutionizes drug development for women's health

Women's bodies and their health in general have for too long been assigned low priority in the field of research.

26 Mar 2024

GPT-4 shows expert-level accuracy in annotating cell types

GPT-4 can accurately interpret types of cells important for the analysis of single-cell RNA sequencing -- a sequencing process fundamental to interpreting cell types – with high consistency to that of time-consuming manual annotation by human experts of gene information, according to a study at Columbia University Mailman School of Public Health.

26 Mar 2024

ABT199/venetoclax synergism with thiotepa enhances cytotoxicity of chemo drugs in AML cells

A new research paper was published in Oncotarget's Volume 15 on March 14, 2024, entitled, "ABT199/venetoclax synergism with thiotepa enhances the cytotoxicity of fludarabine, cladribine and busulfan in AML cells."

26 Mar 2024

Study reveals genetic variant linked to increased risk of leukemia in Hispanic/Latino children

Acute lymphoblastic leukemia (ALL), the most common childhood cancer, disproportionately affects children of Hispanic/Latino origin in the United States.

26 Mar 2024

Study reveals trigonelline as a therapeutic agent for mitochondrial dysfunction in aging

Sarcopenia is the age-related decline in skeletal muscle due to the wasting of myofiber.

26 Mar 2024

Viroclinics-DDL changes name to Cerba Research

Viroclinics-DDL a world-leading vaccine and antiviral specialty laboratory providing research and clinical trial solutions rooted in virology, proudly announces changing its name to Cerba Research as of the 1st of April 2024.

From Cerba Research 26 Mar 2024

Bio-Rad launches validated antibodies for rare cell and circulating tumor cell enumeration

Antibodies validated for use with Bio-Rad’s Celselect Slides™ enumeration stain kits to enable immunostaining of captured circulating tumor cells in liquid biopsy samples.

From Bio-Rad Laboratories 26 Mar 2024

Migraines and other nontraditional factors linked to higher stroke risk in young adults

Adults younger than 35- to 45-years old may have a higher risk of developing a stroke from nontraditional risk factors such as migraines than from traditional risks like high blood pressure.

26 Mar 2024

Vitamin D shows promise in targeting aging's biological mechanisms, study finds

What is currently known about the potential effect of vitamin D (VitD) on modulating some hallmarks of aging.

26 Mar 2024

Study unveils protein signatures for early detection of endometrial cancer in cervico-vaginal fluid

Proteomic signatures in blood plasma and cervicovaginal fluid for endometrial cancer detection.

26 Mar 2024

Vitamin D receptor presence in breast cancer tumors linked to better survival outcomes

Research identifies vitamin D receptors (VDR) in breast cancer tumors as a promising prognostic marker, linking VDR presence to tumor characteristics, survival outcomes, and potentially informing treatment strategies.

25 Mar 2024

Statins show promise in reducing gum disease inflammation

Could taking statins benefit your mouth in addition to your arteries? A new study conducted in cell cultures showed that cholesterol-lowering drugs help to dampen the inflammation associated with periodontal disease by altering the behavior of macrophages, a type of immune cell.

25 Mar 2024

New glycan found to play a key role in nasal colonization of whooping cough bacteria

Researchers have identified a new complex-carbohydrate biomolecule, or glycan, that plays a key role in the nasal colonization of the Bordetella bacteria responsible for whooping cough.

25 Mar 2024

Leveraging cancer therapies to combat tuberculosis

What could cancer teach us about tuberculosis? That's a question Meenal Datta has been chasing since she was a graduate student.

25 Mar 2024

Venetoclax combo opens new treatment path for incurable multiple myeloma

RCSI research has found that venetoclax, a medication currently approved for leukemia, has benefits for patients with multiple myeloma when used in combination with another drug.

25 Mar 2024

Common household chemicals may be linked to neurological diseases

A team of researchers from the Case Western Reserve University School of Medicine has provided fresh insight into the dangers some common household chemicals pose to brain health.

25 Mar 2024

Researchers develop a novel sensor for the detection of bacteria

Each year, bacterial infections claim several million lives worldwide. That is why detecting harmful microorganisms is crucial – not only in the diagnosis of diseases but also, for example, in food production.

25 Mar 2024

NIH funds $12.5 million initiative to create the world's first integrated pancreas knowledgebase

Leading investigators in diabetes, pancreas and islet biology, and computational biology have received $12.5 million in two five-year awards from the National Institutes of Health to create the world's first, integrated knowledgebase of human-derived tissue- and cellular-level pancreatic information to support innovative, collaborative and reproducible research.

25 Mar 2024

B Cell News and Research

New genetic system analyzes the underlying mechanisms of CRISPR-based DNA repair outcomes

Antioxidant-rich diets linked to lower type 2 diabetes risk, supplements less effective

Organ-on-a-chip technology revolutionizes drug development for women's health

GPT-4 shows expert-level accuracy in annotating cell types

ABT199/venetoclax synergism with thiotepa enhances cytotoxicity of chemo drugs in AML cells

Study reveals genetic variant linked to increased risk of leukemia in Hispanic/Latino children

Study reveals trigonelline as a therapeutic agent for mitochondrial dysfunction in aging

Viroclinics-DDL changes name to Cerba Research

Bio-Rad launches validated antibodies for rare cell and circulating tumor cell enumeration

Migraines and other nontraditional factors linked to higher stroke risk in young adults

Vitamin D shows promise in targeting aging's biological mechanisms, study finds

Study unveils protein signatures for early detection of endometrial cancer in cervico-vaginal fluid

Vitamin D receptor presence in breast cancer tumors linked to better survival outcomes

Statins show promise in reducing gum disease inflammation

New glycan found to play a key role in nasal colonization of whooping cough bacteria

Leveraging cancer therapies to combat tuberculosis

Venetoclax combo opens new treatment path for incurable multiple myeloma

Common household chemicals may be linked to neurological diseases

Researchers develop a novel sensor for the detection of bacteria

NIH funds $12.5 million initiative to create the world's first integrated pancreas knowledgebase

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