Genome News and Research

RSS

Using GWAS and trans-ancestry comparison to accurately predict risk for coronary artery disease

An international group led by researchers from the RIKEN Center for Integrative Medical Sciences have used a combination of genome-wide association analysis--or GWAS--and a trans-ancestry comparison of different GWAS studies, to come up with a more accurate predictor of coronary artery disease based on genetic factors.

6 Oct 2020

UChicago genomics researcher wins NIH Director's New Innovator Award

Oni Basu, PhD, an assistant professor of genetic medicine at the University of Chicago, has received the prestigious National Institutes of Health Director's New Innovator Award.

6 Oct 2020

Multi-ancestry comparison can accurately predict risk factors for coronary artery disease

An international group led by researchers from the RIKEN Center for Integrative Medical Sciences have used a combination of genome-wide association analysis—or GWAS—and a trans-ancestry comparison of different GWAS studies, to come up with a more accurate predictor of coronary artery disease based on genetic factors.

6 Oct 2020

SARS-CoV-2 and anti-COVID-19 drugs activate Kaposi sarcoma-associated herpesvirus

A new study published on the preprint server bioRxiv* aimed to investigate the impacts of COVID-19 on people with various illnesses. Specifically, the researchers at the Rockefeller Cancer Institute, and the University of Arkansas for Medical Sciences wanted to see the effects of COVID-19 on patients with cancer and other infectious diseases.

6 Oct 2020

Cancer mutations are found in distinct regions that vary based on genomic structure and mutation

A new study from researchers at The University of Texas MD Anderson Cancer Center has discovered that mutations found in cancers do not accumulate randomly, but are found in distinct patterns that vary based on the three-dimensional organization of the genome in the cell as well as the underlying factors causing the mutations

6 Oct 2020

Researchers identify gene related to seed dispersal in green millet

For years, Elizabeth (Toby) Kellogg, PhD, member and Robert E. King Distinguished Investigator and other researchers at the Donald Danforth Plant Science Center (Danforth Center) drove up and down the highways of the continental United States, occasionally pulling over to the side of the road to collect small weedy plants and bring them back to the lab.

6 Oct 2020

Development of a coarse-grained model of SARS-CoV-2 virion

A team of scientists of the University of Chicago and the University of California San Diego has developed a coarse-grained (CG) model of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virion. The model can be used as a valuable resource to perform multiscale simulations of the SARS-CoV-2 virion. The study is currently available on the bioRxiv* preprint server.

5 Oct 2020

New findings could improve investigation of T cell response to COVID-19

Researchers in the United States have made an important discovery about the processing and presentation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral peptides that provides a better understanding of the immune response to coronavirus disease 2019 (COVID-19) and may help facilitate the design of improved vaccines.

5 Oct 2020

FDA and Mexican regulatory counterparts strengthen partnership on food safety

Today, during a virtual ceremony, the U.S. Food and Drug Administration and its regulatory counterparts in Mexico - the Federal Commission for the Protection from Sanitary Risks and the National Service of Agro-Alimentary Health, Safety and Quality - enhanced a partnership to work together on food safety in both countries.

5 Oct 2020

Midges and mosquitoes unlikely to spread SARS-CoV-2

A recent study published on the preprint server bioRxiv* in September 2020 looked to see if biting insects pose a risk for transmission of SARS-CoV-2 to humans or animals following a SARS-CoV-2 infected blood meal.

5 Oct 2020

More evidence Pangolin not intermediary in transmission of SARS-CoV-2 to humans

The team proposed a different model named the ‘circulation model’ to illustrate how SARS-CoV-2-related coronaviruses could have circulated in different species, including humans, before COVID-19 emerged.

4 Oct 2020

Rapid detection of SARS-CoV-2 with portable CRISPR-based mobile phone diagnostic test

A large group of researchers from the United States reported developing an amplification-free CRISPR-based mobile phone assay for direct detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from nasal swabs. Their state-of-the-art paper is currently available on the medRxiv* preprint server.

4 Oct 2020

Identifying cardiopulmonary processes involved in severe COVID-19

Researchers in the United States have identified cardiopulmonary processes that may partly explain why some individuals with coronavirus disease 2019 (COVID-19) develop respiratory failure.

4 Oct 2020

Shedding light on origin, transmission, spread of COVID-19 in Norfolk

Researchers in the UK have conducted a large-scale whole-genome sequencing study of clinical samples positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the Norfolk area to shed light on the origins, genetic variation, transmission, and spread of the virus in the region.

4 Oct 2020

Anti-sense agents suppress SARS-CoV-2 virus

Researchers in the United States have conducted a study showing that anti-sense agents called peptide-conjugated morpholino oligomers (PPMOs) have the ability to specifically and potently suppress the growth of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

4 Oct 2020

Researchers uncover the cause of 1990s Argentina cholera epidemic

The evolution of epidemic and endemic strains of the cholera-causing bacterium Vibrio cholerae in Argentina has been mapped in detail by researchers at the Wellcome Sanger Institute, the London School of Hygiene and Tropical Medicine, the University of Cambridge and the INEI-ANLIS "Dr Carlos G. Malbrán", Argentina.

1 Oct 2020

In-depth analysis of coronavirus genome sequence in Norfolk identifies hidden outbreaks

An in-depth analysis of the genome sequence of coronavirus circulating in Norfolk, UK by researchers at the Quadram Institute and University of East Anglia has mapped the spread of the virus, identified hidden outbreaks and provided insights into the effectiveness of interventions to stop its spread.

1 Oct 2020

23 SARS-CoV-2 strains circulating in the Philippines

In a new study published on the medRxiv* preprint server, scientists reported coding of complete genome sequences of 23 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains in the Philippines.

1 Oct 2020

Researchers use single-cell sequencing to identify cell types that occur in pancreatic tumors

Led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, and by HonorHealth Research and Innovation Institute, an international team of researchers have described in detail the individual cells that comprise the pancreatic cancer microenvironment, a critical step in devising new treatment options for patients with this aggressive and difficult-to-treat disease.

1 Oct 2020

A detailed map of latent virus reservoir in individuals with HIV

The latent reservoir is the last bastion of HIV's resistance to a cure. But it is difficult to destroy because it is invisible: the cells in the reservoir harbor virus that is dormant, so they don't have any viral proteins on their surface that would give them away.

30 Sep 2020

Genome News and Research

Using GWAS and trans-ancestry comparison to accurately predict risk for coronary artery disease

UChicago genomics researcher wins NIH Director's New Innovator Award

Multi-ancestry comparison can accurately predict risk factors for coronary artery disease

SARS-CoV-2 and anti-COVID-19 drugs activate Kaposi sarcoma-associated herpesvirus

Cancer mutations are found in distinct regions that vary based on genomic structure and mutation

Researchers identify gene related to seed dispersal in green millet

Development of a coarse-grained model of SARS-CoV-2 virion

New findings could improve investigation of T cell response to COVID-19

FDA and Mexican regulatory counterparts strengthen partnership on food safety

Midges and mosquitoes unlikely to spread SARS-CoV-2

More evidence Pangolin not intermediary in transmission of SARS-CoV-2 to humans

Rapid detection of SARS-CoV-2 with portable CRISPR-based mobile phone diagnostic test

Identifying cardiopulmonary processes involved in severe COVID-19

Shedding light on origin, transmission, spread of COVID-19 in Norfolk

Anti-sense agents suppress SARS-CoV-2 virus

Researchers uncover the cause of 1990s Argentina cholera epidemic

In-depth analysis of coronavirus genome sequence in Norfolk identifies hidden outbreaks

23 SARS-CoV-2 strains circulating in the Philippines

Researchers use single-cell sequencing to identify cell types that occur in pancreatic tumors

A detailed map of latent virus reservoir in individuals with HIV

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

Latest News