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COVID-19 vaccine candidate tested preclinically at UAB poised for Phase 1 clinical study

A COVID-19 vaccine candidate that underwent extensive preclinical testing at the University of Alabama at Birmingham this spring and summer is poised for clinical testing to begin in December.

25 Nov 2020

Inhibiting SARS-CoV-2 cell entry with monoclonal antibodies against staphylococcal enterotoxin B superantigen

In a recent cutting-edge study, US researchers unveiled an anti-staphylococcal enterotoxin B monoclonal antibody that can be repurposed to target the cleavage site of the SARS-CoV-2 spike glycoprotein and, in turn, inhibit viral infection. Their findings are currently available on bioRxiv preprint server.

25 Nov 2020

Convalescent plasma therapy ineffective in treating severe COVID-19, study finds

A recent study based at a hospital in Buenos Aires, Argentina, found that convalescent plasma therapy for patients with severe COVID-19, and COVID-19-related pneumonia, was largely ineffective.

25 Nov 2020

Study: None of the SARS-CoV-2 mutations appear to increase transmissibility in humans

None of the mutations currently documented in the SARS-CoV-2 virus appear to increase its transmissibility in humans, according to a study led by UCL researchers.

25 Nov 2020

SARS-CoV-2 spike protein antibodies can persist up to 200 days after symptom onset

Researchers report SARS-CoV-2 antibodies to the spike protein (S protein) can persist 200 days after symptom onset, but that antibodies to the nucleoprotein (N protein) can reduce much more rapidly.

25 Nov 2020

The American Lung Association say to wear masks to stop the spread of COVID-19; Here’s why

Dr. Albert Rizzo speaks to News-Medical about the importance of wearing masks to help control the spread of COVID-19.

25 Nov 2020

Is COVID-19 severity mediated by higher antibody response?

A new study indicates that patients with more severe COVID-19 have a stronger antibody response.

25 Nov 2020

Robust antibody response to SARS-CoV-2 can persist for eight months, study finds

A study conducted by researchers based in Italy suggests that SARS-CoV-2 induces durable and strong immunity in patients who had moderate to severe COVID-19.

25 Nov 2020

Protection of upper respiratory tract will require vaccines that mimic natural infection by SARS-CoV-2

Recently, a team of researchers studied the transmission modes of SARS-CoV-2 and the protection against re-infection in ferret models in work published on the preprint server, bioRxiv.

24 Nov 2020

Mild COVID-19 disease may trigger long-term immunity

Researchers in the United States have conducted a study showing that individuals who have recovered from mild coronavirus disease 2019 (COVID-19) developed sustained protective immune memory against the causative agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

24 Nov 2020

Penn State researcher to study how vitamin D regulates host immunity to viral infection

Funding from the National Institutes of Health will enable a Penn State researcher to study whether vitamin D supplementation could help people ward off or reduce symptoms caused by COVID-19.

24 Nov 2020

The role of micro-RNA in SARS-CoV-2 infection and COVID-19

A team of researchers based in Iran have explored the role of micro-RNA in COVID-19. Their study titled, “The emerging role of microRNAs in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection,” was published in the latest issue of the journal International Immunopharmacology.

24 Nov 2020

Researchers recommend antibody cocktail to tackle SARS-CoV-2 mutations

A new study released on the medRxiv* preprint server indicates that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic – is developing multiple mutations that affect neutralization by antibodies.

24 Nov 2020

Biosensor assay SARS-CoV-2 antibody test may predict COVID-19 severity in patients

Researchers in New York, USA, have found an association of mortality with an early humoral response to SARS-CoV-2 infection within the first few days after onset of symptoms (DAOS), using a highly sensitive and automated testing-on-a-probe (TOP) biosensor assays for SARS-CoV-2.

24 Nov 2020

Mauritian Prime Minister calls upon world leaders to ensure fair distribution of Covid-19 vaccines

Mauritian Prime Minister Pravind Jugnauth calls for Covid-19 vaccines to be ‘distributed fairly’ amid fears that some parts of the world might be left behind in the dash for coronavirus immunity.

24 Nov 2020

New technology can provide immunization against infectious diseases

A single-use, self-administered microneedle technology developed by UConn faculty to provide immunization against infectious diseases has recently been validated by preclinical research trials.

23 Nov 2020

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

A thought-provoking new study reports that the anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike antibodies elicited by natural infection may not be able to neutralize emerging strains that display deletion mutations in their genomic RNA.

23 Nov 2020

Chicago seroprevalence study shows COVID-19 cases 16 times higher than currently predicted

A startling new case study of Chicago, led by a team of researchers at Northwestern University in Illinois, USA, suggests a 16-fold higher incidence of SARS-CoV-2 infection than previously thought. This is judging from seroprevalence (antibody presence blood testing) figures, rather than the number of RT-PCR-positives reported there (via swab sample testing of symptomatic patients).

23 Nov 2020

SARS-Cov-2 antibodies are detected up to 3 months after infection, shows study

A new study in health care workers led by the Barcelona Institute for Global Health (ISGlobal), an institution supported by "la Caixa" Foundation and the Hospital Clínic of Barcelona, shows that IgA and IgM antibodies to SARS-CoV-2 decay quickly, while IgG antibody levels are maintained for at least three months after infection.

23 Nov 2020

Study suggests neutralizing SARS-CoV-2 antibodies offer protection against reinfection

A new study published in November 2020 on the preprint server medRxiv* indicates that the chances of symptomatic infection are indeed much lower among the population with antibodies to the virus.

22 Nov 2020

immunity News and Research

COVID-19 vaccine candidate tested preclinically at UAB poised for Phase 1 clinical study

Inhibiting SARS-CoV-2 cell entry with monoclonal antibodies against staphylococcal enterotoxin B superantigen

Convalescent plasma therapy ineffective in treating severe COVID-19, study finds

Study: None of the SARS-CoV-2 mutations appear to increase transmissibility in humans

SARS-CoV-2 spike protein antibodies can persist up to 200 days after symptom onset

The American Lung Association say to wear masks to stop the spread of COVID-19; Here’s why

Is COVID-19 severity mediated by higher antibody response?

Robust antibody response to SARS-CoV-2 can persist for eight months, study finds

Protection of upper respiratory tract will require vaccines that mimic natural infection by SARS-CoV-2

Mild COVID-19 disease may trigger long-term immunity

Penn State researcher to study how vitamin D regulates host immunity to viral infection

The role of micro-RNA in SARS-CoV-2 infection and COVID-19

Researchers recommend antibody cocktail to tackle SARS-CoV-2 mutations

Biosensor assay SARS-CoV-2 antibody test may predict COVID-19 severity in patients

Mauritian Prime Minister calls upon world leaders to ensure fair distribution of Covid-19 vaccines

New technology can provide immunization against infectious diseases

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

Chicago seroprevalence study shows COVID-19 cases 16 times higher than currently predicted

SARS-Cov-2 antibodies are detected up to 3 months after infection, shows study

Study suggests neutralizing SARS-CoV-2 antibodies offer protection against reinfection

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