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SARS-CoV-2 Omicron variant prompts system sciences and precision medicine

In a new review study, researchers aimed to describe the emergence of the Omicron variant, its structure, its impact on health and health systems, and the challenges that can be expected due to this variant.

21 Feb 2022

Molecular characteristics of SARS-CoV-2 variants enabling antibody escape

A new review paper published in PLoS Pathogens discusses the new variants and the structural mechanism underlying antibody-mediated neutralization as well as mutational antibody escape.

21 Feb 2022

The effect of COVID-19 vaccination on long COVID symptoms

Researchers assessed the effectiveness of COVID-19 vaccines in patients experiencing long COVID.

21 Feb 2022

Surfactant-containing oral mouthwashes target the lipid envelope of SARS-CoV-2

Researchers demonstrated the composition and importance of SARS-CoV-2 lipid envelope and assessed the antiviral potential of oral mouthwashes targeting these lipid envelopes.

21 Feb 2022

Mechanisms of IL-6 expression in peripheral monocyte-derived macrophages infected with SARS-CoV-2

Researchers examined the detailed mechanisms of ‘cytokine storm’ that induces ARDS, often resulting in the death of severely ill COVID-19 patients.

21 Feb 2022

Benchmarking models of SARS-CoV-2 transmission through aerosols and droplets

A new study generated a consolidated set of parameters involving the exhalation of particles.

20 Feb 2022

N-glycosylation blockers reduce SARS-CoV-2 infection

A new Virology study shows that the N-glycosylation pattern of SARS-CoV-2 is crucial to normal spike activity.

20 Feb 2022

Inhalable antibody fragments offer broad protection from SARS-CoV-2 variants

A new study describes a potential new approach to treating COVID-19 in the form of single-chain fragment variable (scFv) antibodies.

20 Feb 2022

T-cell responses linked with protection from SARS-CoV-2 infection in vaccinated individuals with or without cancer

T-cell responses directed against the receptor-binding domain of the SARS-CoV-2 spike protein were associated with protection from SARS-CoV-2 infection in vaccinated individuals with or without cancer, with lower T-cell responses observed in patients with blood cancers.

18 Feb 2022

Music therapy is beneficial for patients with sickle cell disease

A new study from University Hospitals (UH) Connor Whole Health found patients with Sickle Cell Disease (SCD) who participated in music therapy learned new self-management skills and improved their ability to cope with pain.

18 Feb 2022

Codiak's publication highlights the ability of exoASO-STAT6 to selectively target tumor-associated macrophages

Codiak BioSciences, Inc., a clinical-stage biopharmaceutical company pioneering the development of exosome-based therapeutics as a new class of medicines, today announced the online publication of a new manuscript, Exosome mediated genetic reprogramming of tumor associated macrophages by exoASO-STAT6 leads to potent monotherapy anti-tumor efficacy, in the American Association for the Advancement of Science's journal, Science Advances.

18 Feb 2022

New combination of antiviral drugs fails to improve outcomes in hospitalized patients with influenza

A new combination of antiviral drugs did not improve clinical outcomes in hospitalized patients with severe influenza, according results from a recent clinical trial published in The Lancet Infectious Diseases.

18 Feb 2022

Study characterizes COVID-19 vaccine effectiveness at longer dose intervals

Researchers conducted a prospective cohort study to assess the level and durability of protection offered by two doses of COVID-19 vaccine against SARS-CoV-2 infection in participants with no history of a previous infection.

18 Feb 2022

Study reports a highly attenuated SARS-CoV-2 that could serve as a live-attenuated vaccine platform

The research showed a highly attenuated SARS-CoV-2 strain that might be used as a live-attenuated vaccine platform and a BSL-2 experimental system.

18 Feb 2022

Study reveals the structural, functional landscape of neutralizing antibodies against SARS-CoV-2 spike protein

The SARS-CoV-2 virus is continuously evolving and structural changes to the virus may impact the efficacy of antibody therapies and vaccines.

18 Feb 2022

SARS-CoV-2 Mpro inhibitor, nirmatrelvir, found to reduce COVID-19 progression and death

In a new study, researchers evaluated the efficacy and safety of nirmatrelvir in mild to moderate COVID-19 patients who were at high risk of severe COVID-19 disease.

18 Feb 2022

Drugs that increase fetal hemoglobin levels may help people with sickle cell disease

Sickle cell anemia is an inherited blood disorder where red blood cells become sickle/crescent shaped. It causes frequent infections, swelling in the hands and legs, pain, severe tiredness and delayed growth or puberty.

18 Feb 2022

Demonstrating effectiveness of BNT162b2 vaccine in preventing reinfections after COVID-19 recovery

Researchers conducted a retrospective cohort study to assess the rate of SARS-CoV-2 reinfection in patients who had recovered from COVID-19.

18 Feb 2022

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

Researchers evaluated the efficacy of an mRNA vaccine booster dose against severe acute respiratory syndrome coronavirus-2 during the Omicron surge.

18 Feb 2022

Immunogenicity, efficacy, and safety of BNT162b2 or mRNA1273 fourth dose

A recent study explored the safety, immunogenicity, and VE of the SARS-CoV-2 mRNA BNT162b2 and mRNA1273 vaccines against its Omicron VOC in HCWs in Israel.

18 Feb 2022

Efficacy News and Research

SARS-CoV-2 Omicron variant prompts system sciences and precision medicine

Molecular characteristics of SARS-CoV-2 variants enabling antibody escape

The effect of COVID-19 vaccination on long COVID symptoms

Surfactant-containing oral mouthwashes target the lipid envelope of SARS-CoV-2

Mechanisms of IL-6 expression in peripheral monocyte-derived macrophages infected with SARS-CoV-2

Benchmarking models of SARS-CoV-2 transmission through aerosols and droplets

N-glycosylation blockers reduce SARS-CoV-2 infection

Inhalable antibody fragments offer broad protection from SARS-CoV-2 variants

T-cell responses linked with protection from SARS-CoV-2 infection in vaccinated individuals with or without cancer

Music therapy is beneficial for patients with sickle cell disease

Codiak's publication highlights the ability of exoASO-STAT6 to selectively target tumor-associated macrophages

New combination of antiviral drugs fails to improve outcomes in hospitalized patients with influenza

Study characterizes COVID-19 vaccine effectiveness at longer dose intervals

Study reports a highly attenuated SARS-CoV-2 that could serve as a live-attenuated vaccine platform

Study reveals the structural, functional landscape of neutralizing antibodies against SARS-CoV-2 spike protein

SARS-CoV-2 Mpro inhibitor, nirmatrelvir, found to reduce COVID-19 progression and death

Drugs that increase fetal hemoglobin levels may help people with sickle cell disease

Demonstrating effectiveness of BNT162b2 vaccine in preventing reinfections after COVID-19 recovery

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

Immunogenicity, efficacy, and safety of BNT162b2 or mRNA1273 fourth dose

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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