Genetic News and Research

RSS

Unlocking the secrets of our "dark genome": Scientists crack the code of LINE-1

A multidisciplinary study published in Nature has elucidated the structure of the machinery responsible for writing much of our "dark genome" - the 98 percent of our DNA that has largely unknown biological function.

14 Dec 2023

New advance in the development of a test for early diagnosis of cancer

Blood cells reveal tumors in the body. Researchers at the Paul Scherrer Institute achieve an advance with the development of a test for early diagnosis of cancer.

14 Dec 2023

Novel machine learning tool predicts gain- and loss-of-function variants across the genome

In a novel study, researchers from the Icahn School of Medicine at Mount Sinai introduced LoGoFunc, an advanced computational tool that predicts pathogenic gain- and loss-of-function variants across the genome.

14 Dec 2023

Study points to binge drinking and genetics as key factors in liver disease

Those who binge drink and have a certain genetic makeup are six times more likely to develop alcohol-related cirrhosis, according to new research from UCL, the Royal Free Hospital, the University of Oxford and the University of Cambridge.

14 Dec 2023

Study suggests possible targets for the development of a vaccine against multiple sclerosis

Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease in which the Epstein-Barr virus (EBV) is thought to play a role that has not yet been fully clarified.

14 Dec 2023

Association of genetically proxied PDE5 inhibition with measures of fertility, sexual behavior, and wellbeing

Researchers performed a two-sample Mendelian randomization analysis to investigate the associations between genetically proxied suppression of PDE5, a recognized pharmacological target for erectile dysfunction, fertility, subjective wellness, and sexual behavior.

14 Dec 2023

Research shows correlation between neonatal proteins and adult health

Research led by Professor John McGrath from the University of Queensland found that the concentration of the C4 protein, an important part of the immune system, was not associated with risk of mental disorders.

13 Dec 2023

Study finds key gene deletion shields mice from diet-induced obesity and liver disease

Study in the International Journal of Obesity reveals that BMAL1 deletion in mice protects against obesity and non-alcoholic fatty liver disease caused by a high-fat diet, highlighting its potential as a therapeutic target.

13 Dec 2023

Deep learning reveals hidden patterns in adolescent mental health

The personal yet global struggle with mental health may be more visible now than ever before. Yet many people still find it difficult to access the support they need. In Japan, suicide is sadly the leading cause of death for young people.

13 Dec 2023

CRISPR opens doors for novel probiotic functions and applications

Humans can benefit significantly from symbiotic relationships with probiotics - live bacteria and microorganisms that influence the gut microbiota.

13 Dec 2023

Genetic link to premature ovarian insufficiency explained: A mitochondrial perspective

Infertility affects around 48 million couples worldwide and can have various causes. In mammals, including humans, eggs are produced in the ovary.

13 Dec 2023

People with very irregular sleep patterns may have higher dementia risk

People who have very irregular sleep patterns may have a higher risk of dementia than those who have more regular sleep patterns, according to new research published in the December 13, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology.

13 Dec 2023

Protective genetic variant shields Black Americans from kidney disease risk

Many Black Americans who are thought to have a high risk of developing kidney disease possess a protective genetic variant that nullifies the extra risk, a new study from Columbia researchers has found.

12 Dec 2023

OHSU study sheds light on ubiquitin modification during bacterial infection

New research from Oregon Health & Science University could one day lead to therapies that prevent or treat diseases and infections tied to a protein that's found in all human cells.

12 Dec 2023

UK Biobank data shows dose-dependent link between smoking and brain shrinkage

Smoking shrinks the brain, according to a study by researchers at Washington University School of Medicine in St. Louis.

12 Dec 2023

RBD-focused vaccines may offer broader protection against emerging COVID-19 variants

Published in The Lancet's eBioMedicine, 76 healthy adults from Melbourne, aged 18 to 64 who were previously vaccinated with licensed SARS-CoV-2 vaccines, were randomized to receive a fourth dose of a novel protein vaccine, mRNA vaccine or placebo.

12 Dec 2023

Liquid biopsy may offer new tools for personalized immunotherapy in lung cancer

Using a "liquid biopsy" to study genetic material from tumors shed into the bloodstream together with immune cells could help clinicians predict which patients with advanced lung cancers are responding to immunotherapies and which patients may develop immune-related side effects several months later, according to research directed by investigators at the Johns Hopkins Kimmel Cancer Center, the Bloomberg~Kimmel Institute for Cancer Immunotherapy and Allegheny Health Network Cancer Institute in Pittsburgh.

12 Dec 2023

UVA atlas unveils cellular blueprint of atherosclerosis

University of Virginia School of Medicine researchers have created an "atlas of atherosclerosis" that reveals, at the level of individual cells, critical processes responsible for forming the harmful plaque buildup that causes heart attacks, strokes and coronary artery disease.

12 Dec 2023

Bottlenecks in Nucleic Acid Extraction: A Multi-Industrial approach with HiMedia Labs

An interview with Dr. Rajas Warke, Director of Molecular Biology and virology at HiMedia Labs.

From Himedia Laboratories Private Limited 12 Dec 2023

New optimized vaccine approach targets Hepatitis C virus variability

A method to design vaccines for highly variable viruses like the hepatitis C virus.

12 Dec 2023

Genetic News and Research

Unlocking the secrets of our "dark genome": Scientists crack the code of LINE-1

New advance in the development of a test for early diagnosis of cancer

Novel machine learning tool predicts gain- and loss-of-function variants across the genome

Study points to binge drinking and genetics as key factors in liver disease

Study suggests possible targets for the development of a vaccine against multiple sclerosis

Association of genetically proxied PDE5 inhibition with measures of fertility, sexual behavior, and wellbeing

Research shows correlation between neonatal proteins and adult health

Study finds key gene deletion shields mice from diet-induced obesity and liver disease

Deep learning reveals hidden patterns in adolescent mental health

CRISPR opens doors for novel probiotic functions and applications

Genetic link to premature ovarian insufficiency explained: A mitochondrial perspective

People with very irregular sleep patterns may have higher dementia risk

Protective genetic variant shields Black Americans from kidney disease risk

OHSU study sheds light on ubiquitin modification during bacterial infection

UK Biobank data shows dose-dependent link between smoking and brain shrinkage

RBD-focused vaccines may offer broader protection against emerging COVID-19 variants

Liquid biopsy may offer new tools for personalized immunotherapy in lung cancer

UVA atlas unveils cellular blueprint of atherosclerosis

Bottlenecks in Nucleic Acid Extraction: A Multi-Industrial approach with HiMedia Labs

New optimized vaccine approach targets Hepatitis C virus variability

Event guide: 2nd World RNA-Based Therapeutics & Vaccines Summit Korea eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

Latest News