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‘Narrow therapeutic window’ for oxygen in brain injury

Hyperoxia, as well as hypoxia, early after hospital admission is associated with poor outcomes and mortality in patients with traumatic brain injury, report researchers in the Archives of Surgery.

27 Jul 2012

HemoGlobe device can identify women with anemia

Could a low-cost screening device connected to a cell phone save thousands of women and children from anemia-related deaths and disabilities? That's the goal of Johns Hopkins biomedical engineering undergraduates who've developed a noninvasive way to identify women with this dangerous blood disorder in developing nations. The device, HemoGlobe, is designed to convert the existing cell phones of health workers into a "prick-free" system for detecting and reporting anemia at the community level.

25 Jul 2012

New tool uses fluorescence to distinguish cancerous tissue from normal one in low-grade tumors

A new probe developed collaboratively at Norris Cotton Cancer Center and Dartmouth College's Thayer School of Engineering uses an innovative fluorescence-reading technology to help brain surgeons distinguish cancerous tissue from normal tissue. The probe tool, now already in use at the Cancer Center for brain surgery, may one day be used for surgeries for a variety of cancers.

25 Jul 2012

Vanderbilt researchers receives new $2.1M grant to develop microbrain bioreactor

Take a millionth of a human brain and squeeze it into a special chamber the size of a mustard seed. Link it to a second chamber filled with cerebral spinal fluid and thread both of them with artificial blood vessels in order to create a microenvironment that makes the neurons and other brain cells behave as if they were in a living brain. Then surround the chambers with a battery of sensors that monitor how the cells respond when exposed to minute quantities of dietary toxins, disease organisms or new drugs under development.

25 Jul 2012

Hypoxic lung environment increases HIF-2a tumor growth signaling

In addition to the well-known risk factor of smoking, chronic obstructive pulmonary disease (COPD) increases lung cancer risk.

25 Jul 2012

Viewpoints: Cutting health costs is next battle; Texas Medicaid chief on why expansion won't work; Grief, anger over end-of-life decision

No matter what happens to President Obama's health care reforms after the November elections, the disjointed, costly American health care system must find ways to slow the rate of spending while delivering quality care. There is widespread pessimism that anything much can be achieved quickly, but innovative solutions are emerging in unexpected places. A health care system owned and managed by Alaska's native people has achieved astonishing results in improving the health of its enrollees while cutting the costs of treating them.

24 Jul 2012

University of Utah chemist wins 2013 Priestley Medal from ACS

Only months after collecting a National Medal of Science from President Barack Obama, University of Utah organic chemist Peter J. Stang has won the highest honor from the world's largest scientific group: the 2013 Priestley Medal from the American Chemical Society.

23 Jul 2012

Study explores role of L. reuteri against foodborne infection

While many bacteria exist as aggressive pathogens, causing diseases ranging from tuberculosis and cholera, to plague, diphtheria and toxic shock syndrome, others play a less malevolent role and some are critical for human health.

21 Jul 2012

Covidien receives Brazilian approval for Solitaire FR Revascularization Device

Covidien, a leading global provider of healthcare products, today announced that the Solitaire FR Revascularization Device has been approved by Brazil's National Health Surveillance Agency. The Solitaire FR device is used to restore blood flow to the brain in patients suffering acute ischemic stroke.

20 Jul 2012

Hyperoxygenation postsurgery benefits in doubt

Supplementation with 80% fraction of inspired oxygen during surgery does not reduce patients’ risk for surgical site infections, research shows.

19 Jul 2012

Research explains why exercise is beneficial for heart function in type 2 diabetes

A detailed study of heart muscle function in mice has uncovered evidence to explain why exercise is beneficial for heart function in type 2 diabetes. The research team, led by scientists at the Johns Hopkins University School of Medicine, found that greater amounts of fatty acids used by the heart during stressful conditions like exercise can counteract the detrimental effects of excess glucose and improve the diabetic heart's pumping ability in several ways.

18 Jul 2012

PPAHS releases safety checklist that targets Patient-Controlled Analgesia

The Physician-Patient Alliance for Health & Safety (PPAHS), an advocacy group devoted to improving patient health and safety, today announced the release of a concise checklist that reminds caregivers of the essential steps needed to be taken to initiate Patient-Controlled Analgesia (PCA) with a patient and to continue to assess that patient's use of PCA.

18 Jul 2012

Researchers uncover mechanism by which aging may weaken immune response

Researchers at Albert Einstein College of Medicine of Yeshiva University have uncovered one of the mechanisms by which aging may compromise the ability of the immune system to fight infections and respond to vaccines.

18 Jul 2012

How does exercise improve heart function in diabetics?

A detailed study of heart muscle function in mice has uncovered evidence to explain why exercise is beneficial for heart function in type 2 diabetes.

18 Jul 2012

Promising path to Parkinson’s disease treatment

Using adult stem cells, Johns Hopkins researchers and a consortium of colleagues nationwide say they have generated the type of human neuron specifically damaged by Parkinson’s disease (PD) and used various drugs to stop the damage.

17 Jul 2012

WCMC receives NHLBI grant to study smoking-induced COPD

Researchers at Weill Cornell Medical College were awarded a $6.5 million grant from the National Heart, Lung, and Blood Institute for a five-year investigation into metabolic changes occurring within airway epithelial cells in the lungs of chronic obstructive pulmonary disease (COPD) patients caused by cigarette smoking. In addition, researchers aim to identify which cigarette smokers are at highest risk of developing COPD as well as novel biomarkers to assist in the development of new therapeutic treatments for the disease.

17 Jul 2012

Mitochondrial gene regulators involved in Huntington’s disease pathology

Researchers have identified two molecules involved in mitochondrial function that appear to be important in the pathogenesis of Huntington’s disease.

16 Jul 2012

Two cellular proteins team up to provide steady supply of RBCs

Two cellular proteins team up to provide a steady supply of red blood cells (RBCs), according to a study by Lizhao Wu, PhD, of the University of Medicine and Dentistry of New Jersey-New Jersey Medical School, and colleagues.

14 Jul 2012

SLU professor to study how antithrombin might prevent premature death from heart disease

Alireza "Ray" Rezaie, Ph.D., professor of biochemistry and molecular biology at Saint Louis University School of Medicine, has received a $1.52 million NIH grant to study how the key blood clotting inhibitor antithrombin might be exploited to prevent premature death from heart disease.

12 Jul 2012

Researchers settle controversy over the mechanism by which silver nanoparticles kill bacteria

Rice University researchers have settled a long-standing controversy over the mechanism by which silver nanoparticles, the most widely used nanomaterial in the world, kill bacteria.

12 Jul 2012