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UCL scientists receive £997,000 from the Type 1 Diabetes Grand Challenge

Scientists at the UCL Institute of Immunity & Transplantation (IIT) are part of a team to receive £997,000 from the Type 1 Diabetes Grand Challenge, a new partnership involving The Steve Morgan Foundation, Diabetes UK and JDRF.

19 Dec 2023

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

Researchers investigated the anticancer effects of drugs targeting human tumor-associated macrophages (TAMs) in vivo. In humanized murine models, they tested the effectiveness of an antibody to human signal regulatory protein alpha (SIRPα) for cancer immunotherapy.

19 Dec 2023

Patients facing death are opting for a lifesaving heart device — but at what risk?

Too old and too sick for a heart transplant, Arvid Herrman was given a choice: Have a mechanical pump implanted in his heart, potentially keeping him alive for several years, or do nothing and almost certainly die within a year.

19 Dec 2023

New study challenges "gold standard" opioid treatment for cancer pain

Researchers examining the data on opioids for pain caused by cancer have found surprisingly large gaps in evidence regarding the true benefits of these medicines for cancer pain.

18 Dec 2023

Two new practice parameters offer recommendations for treating anaphylaxis and atopic dermatitis

Two new practice parameters from the Joint Task Force for Practice Parameters (JTFPP) offer evidence-based recommendations for the diagnosis and management of anaphylaxis and atopic dermatitis (AD) in pediatric and adult patients.

18 Dec 2023

Social vulnerability linked to unhealthy lifestyles and poor health in the US, study finds

Study in The American Journal of Medicine reveals that increased social vulnerability in the US leads to worse lifestyle behaviors and health characteristics, with distinct geographic disparities calling for precision medicine approaches.

18 Dec 2023

Shattering myths: Study reveals new insights on type 1 diabetes and obesity link

Review examines the relationship between type 1 diabetes and weight disorders, debunking myths about T1D and offering recommendations for future research and therapeutic interventions.

18 Dec 2023

How exercise battles muscle fat: New gene holds the answer

Myosteatosis, or aging-related fat accumulation in skeletal muscles, is a leading cause of declines in muscle strength and quality of life in elderly adults.

18 Dec 2023

New study casts doubt on effectiveness of opioids for cancer pain

The world's largest review on opioid medicines for cancer pain has found it is unclear whether some commonly used opioid medicines are better than a placebo and suggests that non-opioid medicines, including aspirin, may be as effective as opioids.

18 Dec 2023

New discovery could expand the possibilities for medical use of Botox

PSI researchers have discovered a surprising trick that could expand the possibilities for medical use of botulinun toxin A1, better known under the name Botox, as an active agent.

18 Dec 2023

Psilocybin may benefit individuals with cancer and major depression

Results from a phase II clinical trial indicate that psilocybin, a hallucinogenic chemical found in certain mushrooms of the genus Psiloybe, may benefit individuals with cancer and major depression.

18 Dec 2023

Only 1 in 18 people with opioid use disorder get effective treatment after overdose

In the week following any hospital visit for an overdose, only 1 in 18 people with opioid use disorder begin a treatment known to be highly effective in reducing illness and deaths, according to new research in CMAJ (Canadian Medical Association Journal).

18 Dec 2023

Antibody treatment shields transplant patients against COVID-19

New research from Cedars-Sinai's Comprehensive Transplant Center found that a monoclonal antibody treatment reduced the risk of COVID-19 in a large group of solid organ transplant patients who were administered the drug as a preventive measure against the disease.

18 Dec 2023

Study supports limiting red meat intake for type 2 diabetes prevention, highlights alternative protein sources

Study finds that consumption of red, processed, and unprocessed meat significantly increases the risk of type 2 diabetes, suggesting the benefits of substituting meat with nuts, legumes, and dairy.

17 Dec 2023

Global study emphasizes early detection of familial hypercholesterolaemia in youth

Study on familial hypercholesterolaemia in children and adolescents from 48 countries highlights the need for early detection and management to prevent cardiovascular diseases.

17 Dec 2023

Experimental drug paired with a standard-care medication offers hope for kidney disease patients

In a clinical trial of patients with chronic kidney disease, an experimental drug significantly reduced albuminuria - albumin in urine, a sign of kidney damage - for 50% of participants.

15 Dec 2023

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

A new study finds that radiation therapy (RT) suppresses a key protein called bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) and activates immune suppressive cells.

15 Dec 2023

New LMU-led DFG Research Unit eyes innovative gene therapies for retinal diseases

A new LMU-led DFG Research Unit is developing innovative approaches for treating retinal diseases.

15 Dec 2023

QUT scientists discover promising treatment for fatal endometrial cancer

QUT scientists have discovered a promising new therapy for a deadly type of endometrial cancer that has a poor prognosis if the cancer spreads or returns after initial treatment, a plight that affects 15-20 per cent of endometrial cancer patients.

15 Dec 2023

Blueprint Medicines announces approval of AYVAKYT for treatment of ISM patients in Europe

Blueprint Medicines Corporation today announced the European Commission has approved AYVAKYT® (avapritinib) for the treatment of adult patients with indolent systemic mastocytosis (ISM) with moderate to severe symptoms inadequately controlled on symptomatic treatment. AYVAKYT is the first and only approved therapy for people living with ISM in Europe.

15 Dec 2023

Therapy News and Research

UCL scientists receive £997,000 from the Type 1 Diabetes Grand Challenge

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

Patients facing death are opting for a lifesaving heart device — but at what risk?

New study challenges "gold standard" opioid treatment for cancer pain

Two new practice parameters offer recommendations for treating anaphylaxis and atopic dermatitis

Social vulnerability linked to unhealthy lifestyles and poor health in the US, study finds

Shattering myths: Study reveals new insights on type 1 diabetes and obesity link

How exercise battles muscle fat: New gene holds the answer

New study casts doubt on effectiveness of opioids for cancer pain

New discovery could expand the possibilities for medical use of Botox

Psilocybin may benefit individuals with cancer and major depression

Only 1 in 18 people with opioid use disorder get effective treatment after overdose

Antibody treatment shields transplant patients against COVID-19

Study supports limiting red meat intake for type 2 diabetes prevention, highlights alternative protein sources

Global study emphasizes early detection of familial hypercholesterolaemia in youth

Experimental drug paired with a standard-care medication offers hope for kidney disease patients

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

New LMU-led DFG Research Unit eyes innovative gene therapies for retinal diseases

QUT scientists discover promising treatment for fatal endometrial cancer

Blueprint Medicines announces approval of AYVAKYT for treatment of ISM patients in Europe

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