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Advanced imaging reveals the loss of brain synapses in patients with mild symptoms of Alzheimer's

Advanced imaging technology developed by Yale researchers has helped them confirm that the destruction of brain synapses underlies the cognitive deficits experienced by patients with Alzheimer's disease, according to a study published Feb. 17 in the journal Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

17 Feb 2022

Intermediate size nanoparticles may be effective at stopping internal bleeding

Traumatic injuries are the leading cause of death in the U.S. among people 45 and under, and such injuries account for more than 3 million deaths per year worldwide.

17 Feb 2022

Study to evaluate efficacy of higher dose of ivermectin for treating mild-to-moderate COVID-19

A study led by the Duke Clinical Research Institute (DCRI) in partnership with Vanderbilt University has expanded its testing platform to evaluate ivermectin at a higher dose for a longer period of time.

17 Feb 2022

Trial of early antiviral therapy for COVID-19 shows no significant benefit

A new preprint research paper examines the efficacy of using three antivirals in various combinations in early infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Feb 2022

KHN’s ‘What the Health?’: It’s health costs, stupid (2022 edition)

The pandemic may be showing signs of winding down, but health care costs are not.

17 Feb 2022

ChAdOx1 vaccine found to protect Syrian hamsters against SARS-CoV-2 variants

Researchers recently evaluated the efficacy of the Oxford ChAdOx1 (AZD 1222/ AZD2816) vaccine against the Omicron, Delta, and Beta variants of SARS-CoV-2 in Syrian hamsters.

17 Feb 2022

mRNA COVID-19 vaccine shown to induce afucosylated antibodies in individuals without prior SARS-CoV-2 exposure

New study findings reveal that the level of afucosylated anti-spike antibodies increases transiently in infection-naïve individuals after the first COVID-19 vaccine dose.

17 Feb 2022

A novel consensus-based computational pipeline that reliably predicts hACE2-RBD binding affinity

Researchers developed a novel computational model to predict the binding affinity between the hACE2 receptor and the RBD of S protein of SARS-CoV-2.

17 Feb 2022

Detection of SARS-CoV-2 RNA by plasmonic-magnetic nanorobots

Researchers present a simple and efficient plasmonic-magnetic nanorobot for the detection of SARS-CoV-2 RNA.

16 Feb 2022

Study helps understand actionable genetic variation affecting drugs in the Middle East population

A group of researchers at Qatar Foundation have reported the first comprehensive study of the distribution of actionable genetic variation affecting drugs in any Middle Eastern population, with potential implications for preemptive pharmacogenomic implementation in the region.

16 Feb 2022

Innovative coating kills SARS-CoV-2 and E. coli

Researchers develop a low-cost, non-toxic, and scalable antimicrobial polymer that can be functionalized on diverse fabrics.

16 Feb 2022

UC joins nationwide trial to evaluate efficacy of repurposed drugs for mild-to-moderate COVID-19

The University of Cincinnati is joining a nationwide study to evaluate repurposed medications in the search for effective, safe treatments for mild-to-moderate COVID-19. Repurposed medications are those already approved by the U.S. Food and Drug Administration for other indications.

16 Feb 2022

SARS-CoV-2 variants are evolving increased infectivity and antibody escape, studies say

First announced by the World Health Organization on Nov. 26, 2021, the SARS-CoV-2 omicron variant spread rapidly around the world, becoming the dominant variant in the U.S. and elsewhere.

16 Feb 2022

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

A new study discusses the state of current knowledge about the potential use of tea polyphenols in the prevention and treatment of COVID-19.

16 Feb 2022

Study examines lyophilized mRNA-lipid nanoparticle vaccines with long-term stability

A new study explored the high immunogenicity and stability of lyophilized mRNA-LNP vaccines in relation to SARS-CoV-2.

16 Feb 2022

Impact of Omicron on COVID-19 prevalence among unvaccinated and vaccinated in Omicron-dominated countries

Scientists have recently explored the impact of the omicron variant of SARS-CoV-2 on the prevalence of COVID-19 in vaccinated and unvaccinated individuals.

16 Feb 2022

Human nose organoids provide better understanding of the first steps toward SARS-CoV-2 infection

Preclinical models that recapitulate aspects of human airway disease are essential for the advancement of novel therapeutics and vaccines.

16 Feb 2022

Two doses of psilocybin may ease depression symptoms for up to 12 months

Previous studies by Johns Hopkins Medicine researchers showed that psychedelic treatment with psilocybin relieved major depressive disorder symptoms in adults for up to a month.

15 Feb 2022

Research suggests SARS-CoV-2 viral accessory proteins may play significant role in viral evolution

Researchers investigate SARS-CoV-2 mutations present across the whole genome of different SARS-CoV-2 variants.

15 Feb 2022

New tool appears to accurately identify patients at risk of death from alcohol-associated hepatitis

Mayo Clinic researchers have developed a new scoring system to help health care professionals predict the 30-day mortality risk for patients with alcohol-associated hepatitis, and the tool appears to more accurately identify patients at highest risk of death and those likely to survive.

15 Feb 2022

Efficacy News and Research

Advanced imaging reveals the loss of brain synapses in patients with mild symptoms of Alzheimer's

Intermediate size nanoparticles may be effective at stopping internal bleeding

Study to evaluate efficacy of higher dose of ivermectin for treating mild-to-moderate COVID-19

Trial of early antiviral therapy for COVID-19 shows no significant benefit

KHN’s ‘What the Health?’: It’s health costs, stupid (2022 edition)

ChAdOx1 vaccine found to protect Syrian hamsters against SARS-CoV-2 variants

mRNA COVID-19 vaccine shown to induce afucosylated antibodies in individuals without prior SARS-CoV-2 exposure

A novel consensus-based computational pipeline that reliably predicts hACE2-RBD binding affinity

Detection of SARS-CoV-2 RNA by plasmonic-magnetic nanorobots

Study helps understand actionable genetic variation affecting drugs in the Middle East population

Innovative coating kills SARS-CoV-2 and E. coli

UC joins nationwide trial to evaluate efficacy of repurposed drugs for mild-to-moderate COVID-19

SARS-CoV-2 variants are evolving increased infectivity and antibody escape, studies say

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

Study examines lyophilized mRNA-lipid nanoparticle vaccines with long-term stability

Impact of Omicron on COVID-19 prevalence among unvaccinated and vaccinated in Omicron-dominated countries

Human nose organoids provide better understanding of the first steps toward SARS-CoV-2 infection

Two doses of psilocybin may ease depression symptoms for up to 12 months

Research suggests SARS-CoV-2 viral accessory proteins may play significant role in viral evolution

New tool appears to accurately identify patients at risk of death from alcohol-associated hepatitis

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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