Muscle News and Research

RSS

KU Cancer Center to present evidence supporting anti-cancer drug at AACR 2018

The University of Kansas Cancer Center will present preclinical evidence supporting Ciclopirox Prodrug (CPX-POM), an anti-cancer agent currently in Phase I clinical trials, at the American Association for Cancer Research 2018 Annual Meeting in Chicago. Ciclopirox Prodrug was discovered by researchers at The University of Kansas Cancer Center and KU's Institute for Advancing Medical Innovation.

12 Apr 2018

LSD1 enzyme regulates skeletal muscle differentiation and metabolic activity

Our bodies convert food into energy for all life activities. These metabolic processes allow the cells that make up our bodies to produce (anabolism) and consume (catabolism) energy molecules from nutrients.

12 Apr 2018

Aberrant protein prevents self-cleaning of nerve cells in ALS

Scientists have discovered that TDP-43 interferes with lysosomal pathways responsible for its clearance and induces autophagy in ALS.

12 Apr 2018

Researcher explores how children develop immunity to malaria as they grow older

Across the world, over 200 million cases of malaria and nearly 500,000 deaths from the disease occur annually--more than 90 percent of which happen in Africa. Children in Africa can be diagnosed with malaria two or three times a year, a rate that decreases as they become older and develop immunity. But the way children generate and maintain this immunity remains a mystery.

11 Apr 2018

Is there such a thing as normal aging?

For 93-year-old Joseph Brown, the clearest sign of aging was his inability the other day to remember he had to have his pants unzipped to pull them on.

11 Apr 2018

Removal of single mitochondrial protein leads to severe inflammation

The link between mitochondria and inflammation is still unclear. But it is known is that, for example, the accumulation of defective mitochondria, which should have been removed, causes inflammation.

10 Apr 2018

Cardiac fibroblasts contribute to heart disease

An article published in Experimental Biology and Medicine reports that supporting cells in the heart, known as fibroblasts, are selectively activated by factors present in heart disease.

9 Apr 2018

New leadless pacemakers carry reduced risks of complications and are less invasive

Loyola Medicine is now offering select heart patients leadless pacemakers that are less invasive and cause fewer complications than standard pacemakers.

9 Apr 2018

Resistance training enhances cellular recycling in muscle cells

A new study has shown that resistance training among previously untrained men increases autophagosome content, but that this effect may be blunted by aging.

9 Apr 2018

Breast cancer survival linked to muscle mass finds study

Researchers have found that women with breast cancer who have a low muscle mass are less likely to survive stage 2 and 3 cancers. The study titled, “Association of Muscle and Adiposity Measured by Computed Tomography with Survival in Patients with Nonmetastatic Breast Cancer,” appears in the latest issue of the journal JAMA Oncology.

9 Apr 2018

Newly expanded program at Rush offers relief from pelvic floor problems

Trouble with urine or bowel control, bladder pain, recurring urinary tract infections, constipation and other sexual function issues frequently can be traced to a dysfunctional pelvic floor -- the layer of muscles that support the bladder and bowel in men, and bladder, bowel and vagina in women.

6 Apr 2018

Researchers study how often healthcare providers prescribe anticholinergics for older adults

Anticholinergics are a class of medications that are often prescribed for allergies, lung disease, and urinary incontinence. They also often can increase health risks for older adults.

5 Apr 2018

Researchers create adult-like cardiac model by introducing early stimulation

Researchers are now able to use induced pluripotent stem cells to form a model of human adult-like cardiac muscle by introducing electric and mechanical stimulation at an early stage. Since this muscle is similar to the adult heart, it could serve as a better model for testing the effects of drugs and toxic substances than current tissue engineered heart models.

5 Apr 2018

New discovery may offer insight into treating sickle cell anemia and other blood disorders

Discovery by Scripps Research scientists may offer insight into treating blood disorders such as sickle cell anemia.

4 Apr 2018

Pitt engineer uses ultrasound technology to help people walk again

Spinal cord injuries impact more than 17,000 Americans each year, and although those with incomplete injuries may regain control of their limbs, overall muscle strength and mobility is weakened. Neurorehabilitation using robotic exoskeletons or electrical stimulation devices can help a person regain movement through repeated exercise.

3 Apr 2018

Exercise and diet can help fight side effects of hormone therapy in prostate cancer patients

Men on hormone therapy for prostate cancer may benefit significantly from hitting the gym with fellow patients and choosing more veggies and fewer cheeseburgers, a new study suggests.

3 Apr 2018

Resistance exercise may improve indicators of type 2 diabetes, study suggests

A new study suggests that resistance exercise may improve indicators of type 2 diabetes by increasing expression of a protein that regulates blood sugar (glucose) absorption in the body.

3 Apr 2018

Higher protein intake may not benefit older adults

Regardless of whether an adult is young or old, male or female, their recommended dietary allowance for protein, set by the Institute of Medicine, is the same: 0.8-g/kg/day. Many experts and national organizations recommend dietary protein intakes greater than the recommended allowance to maintain and promote muscle growth in older adults.

2 Apr 2018

UTA professor wins AHA grant to study biomechanical influences on ventricular development

A University of Texas at Arlington researcher is working to determine how blood flow and cardiac muscle contraction affects gene development that leads to ventricular chamber development in the heart.

31 Mar 2018

Cancers may be detected at smaller size in breasts with implants, study reveals

Breast augmentation with implants does not interfere with the ability to detect later breast cancers--in fact, cancers may be detected at a smaller size in breasts with implants, according to a study in the April issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

29 Mar 2018