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Brigatinib drug shows promise against ALK+ non-small cell lung cancer in phase I/II clinical trial

Phase I/II clinical trial results reported at the American Society for Clinical Oncology (ASCO) Annual Meeting 2015 show promising results for investigational drug brigatinib against ALK+ non-small cell lung cancer (NSCLC), with 58 of 78 ALK+ patients responding to treatment, including 50 of 70 patients who had progressed after previous treatment with crizotinib, the first licensed ALK inhibitor.

28 May 2015

University of Gothenburg studies reveal that linalyl acetate can trigger allergic eczema

Linalyl acetate, a fragrance chemical that is one of the main constituents of the essential oil of lavender, is not on the list of allergenic compounds pursuant to the EU Cosmetics Directive. Thus, it does not need to be declared on cosmetic products sold within the EU. Recent studies at the University of Gothenburg have shown that linalyl acetate can cause allergic eczema.

28 May 2015

FEV1/FVC lower limit of normal aids surgery risk stratification in COPD

Researchers say that using the lower limit of normal of the forced expiration volume in 1 second/forced vital capacity ratio improves risk stratification in patients with chronic obstructive pulmonary disease undergoing thoracic surgery.

27 May 2015

$Study analyses advantages of using fractions of ejaculate in IVF$

Study analyses advantages of using fractions of ejaculate in IVF

Sperm in the first fraction of ejaculate are more numerous, move more and present better quality DNA than those lagging behind. This is the conclusion of a study led by the Ginemed fertility clinic, which confirms that while the objective of the first fraction is to fertilise the egg, the second phase is so that no sperm from any other male has a chance to fertilise it.

27 May 2015

Study could offer new way to treat, prevent diabetes-associated blindness

Reporting on their study with lab-grown human cells, researchers at The Johns Hopkins University and the University of Maryland say that blocking a second blood vessel growth protein, along with one that is already well-known, could offer a new way to treat and prevent a blinding eye disease caused by diabetes.

26 May 2015

National Jewish Health researcher calls for men to be included in osteoporosis screening guidelines

Most people associate osteoporosis with women. But the truth is, one in four men over the age of 50 will break a bone as a result of this condition. That's more men than will have prostate cancer, according to the National Osteoporosis Foundation.

21 May 2015

New study suggests ways to accelerate recovery from dangerous diarrheal disease

A new study delineates a sequential pattern of changes in the intestinal microbial population of patients recovering from cholera in Bangladesh, findings that may point to ways of speeding recovery from the dangerous diarrheal disease.

20 May 2015

Vitamin E helps build strong muscles

Body builders have it right: vitamin E does help build strong muscles, and scientists appear to have figured out one important way it does it.

19 May 2015

Presentation at International Headache Congress shows electroCore’s chronic cluster headache treatment to be cost-effective

Cluster headache is one of the worst pain conditions known to medical science and has few preventative treatment options, many of which have severe side effects...

19 May 2015

fMRI reflects interactions between brain regions

Tübingen neuroscientists have made an important advance in studying the human brain with functional magnetic resonance imaging (fMRI).

18 May 2015

Findings support use of high-flow nasal oxygen therapy to treat postoperative respiratory failure

A relatively new, easier to implement, and better-tolerated method to provide supplemental oxygen to patients at risk of respiratory failure after surgery did not result in a worse rate of treatment failure compared to a more commonly used method, according to a study appearing in JAMA.

18 May 2015

WHO Regional Office for the Eastern Mediterranean press release: WHO delivers additional medicines and medical supplies into Yemen

WHO is also providing a shipment of anti-malaria medicines from the Global Fund to Fight AIDS, Tuberculosis and Malaria sufficient for 44 950 treatment courses of malaria...

15 May 2015

Long, non-coding RNAs play a role in heart attacks, strokes and cancer

About 70 percent of our genes provide the blueprint for biomolecules whose function is only now being discovered - non-coding RNAs. Instead of being translated into proteins, they seem to perform steering functions in the body.

14 May 2015

Volkan Sayin receives Assar Gabrielsson Award for ground-breaking study on use of anti-oxidants

The Assar Gabrielsson Award is given to someone who has written an excellent thesis on cancer research. The 2015 award-winner is Volkan Sayin, and he receives the award for his ground-breaking discoveries about the risks of over-consumption of anti-oxidants.

13 May 2015

Save the date: MEDICA and COMPAMED from 16 – 19 November 2015

Planning is already running at full blast for the MEDICA 2015 and COMPAMED 2015 being held in parallel...

13 May 2015

Merck KGaA, Darmstadt, Germany granted FDA Fast Track designation for development of evofosfamide

Merck KGaA, Darmstadt, Germany, a leading company for innovative and top-quality high-tech products in healthcare, life science and performance materials today announced that the U.S. Food and Drug Administration has granted Fast Track designation for the development of evofosfamide (previously known as TH-302), administered in combination with gemcitabine, for the treatment of previously untreated patients with metastatic or locally advanced unresectable pancreatic cancer.

12 May 2015

Discovery may have opened up new frontier in fight against breast cancer

For years, scientists have been puzzled by the presence of short stretches of genetic material floating inside a variety of cells, ranging from bacteria to mammals, including humans. These fragments are pieces of the genetic instructions cells use to make proteins, but are too short a length to serve their usual purpose.

8 May 2015

UT Southwestern testing Vivistim System device in stroke patients

UT Southwestern Medical Center will be one of three national sites to pioneer U.S. testing for an implant device that stimulates the vagus nerve in stroke patients to see whether it can help restore lost arm function.

7 May 2015

Relaxation response has significant impact on patients with gastrointestinal disorders

A pilot study has found that participating in a nine-week training program including elicitation of the relaxation response had a significant impact on clinical symptoms of the gastrointestinal disorders irritable bowel syndrome and inflammatory bowel disease and on the expression of genes related to inflammation and the body's response to stress.

6 May 2015

Researchers study early response of cells to ischemia

A group of researchers from the Lomonosov Moscow State University in collaboration with their Irish colleagues from the University College Cork has studied the early response of cells to ischemia, which is a restriction in blood supply to tissues causing the death of the cell.