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Study: Checkpoint inhibitor prolongs survival in patients with head and neck cancers

The checkpoint inhibitor pembrolizumab (Keytruda) offers patients with advanced head and neck cancers longer survival time, according to a new global study led by Yale Cancer Center (YCC). The data was published today in the journal The Lancet.

1 Nov 2019

UI scientists are developing new delivery tools for gene editing

News of advances in gene-editing technology raises the prospect of actually using this approach to treat disease in patients. But one of the hurdles that remains is how to deliver these tools to the right cells in the patients safely and efficiently.

31 Oct 2019

Risky strategy allows malaria parasite to quickly respond to unpredictable changes

The parasite that causes malaria expresses genes that code for the proteins it will need in later life stages, using two separate schemes to prevent these proteins from actually being made until they are needed, according to new research.

31 Oct 2019

Doctors report first death from fecal microbiota transplant

Details of an investigational study have emerged after a man died following a fecal microbiate transplant. The events prompted the FDA to set new safety guidelines for the practice.

31 Oct 2019

Researchers identify genes linked to most severe symptoms of multiple sclerosis

In a bid to determine factors linked to the most debilitating forms of multiple sclerosis, Johns Hopkins Medicine researchers say they have identified three so-called "complement system" genes that appear to play a role in MS-caused vision loss.

From Johns Hopkins Medicine 31 Oct 2019

Robotic-assisted surgery can improve longevity of knee replacement

Forty-nine-year-old James Benfante's knee pain got so bad he dreaded walking from the train station to his job or even standing in line.

31 Oct 2019

Education may erase risk of cognitive decline linked to APOE e4 gene in black people

Education may erase the risk of cognitive decline associated with the APOE e4 gene--the biggest genetic risk factor for late-onset Alzheimer's disease--in older non-Hispanic black people, according to a new study by researchers at Columbia University Vagelos College of Physicians and Surgeons.

30 Oct 2019

New study finds racial/ethnic variation in discharge destination after knee replacement surgery

A large study analyzing 107,000 knee replacement surgeries found that African Americans were significantly more likely than white patients to be discharged to an inpatient rehabilitation or skilled nursing facility rather than home care after the procedure. Researchers also found that African American patients under 65 were more likely to be readmitted to the hospital within 90 days of a knee replacement.

30 Oct 2019

CEM enters into a definitive agreement to purchase key assets of Intavis Bioanalytical Instruments

CEM Corporation today announced that it has entered into a definitive agreement to purchase the instrumentation lines of Intavis Bioanalytical Instruments AG, with headquarters in Cologne Germany. The acquisition allows CEM to strengthen its product offering in the Life Sciences for proteomics, in-situ hybridization and particularly in the field of peptide synthesis.

From CEM Corporation - Life Science 30 Oct 2019

New collaborative effort focuses on therapeutic research for CDKL5 Deficiency Disorder

CDKL5 Deficiency Disorder is a devastating neurodevelopmental disorder caused by mutations in the CDKL5 gene.

30 Oct 2019

DNA sequences encode information in many different ways

DNA sequences encode information in many different ways. Codons specify the amino acids involved in making a protein.

30 Oct 2019

Poverty, race have no impact on total knee replacement revision or failure

Previous studies have established that black patients have a higher risk for knee replacement revision. Black patients also report significantly more pain and worse joint function two years after surgery compared to white patients.

29 Oct 2019

Rutgers selected to speed up development of biomedical health technologies

Rutgers, The State University of New Jersey was selected as one of five new hubs under the National Institutes of Health's Research Evaluation and Commercialization Hubs program to speed up the translation of biomedical discoveries into commercially viable diagnostics, devices, therapeutics, and tools to improve patient care, enhance health, and train the next generation of innovators.

29 Oct 2019

Researchers make progress toward gene-based strategies to treat inherited neurometabolic diseases

Researchers are making great strides toward developing gene-based strategies to treat a variety of inherited neurometabolic diseases characterized by severe neurological involvement.

29 Oct 2019

First effective noninvasive method for diagnosing early-stage liver diseases

A safer and more sensitive contrast dye for MRI tests developed by a team led by Georgia State University researchers may provide the first effective, noninvasive method for detecting and diagnosing early-stage liver diseases, including liver fibrosis.

29 Oct 2019

Femtogenix announces new data on ADCs containing reduced potency payloads in solid tumor models

Femtogenix Ltd, a UK biotechnology company developing the next generation of DNA-interactive Antibody Drug Conjugate payloads, today announced data demonstrating the potent efficacy and favorable toxicity profile of a reduced potency analogue from its Pyridinobenzodiazepine ADC payload platform in solid tumor models.

From Pheon Therapeutics 29 Oct 2019

Pro-inflammatory protein could play key role in protecting against herpes virus

Researchers at the University of Arizona College of Medicine - Phoenix have discovered a function in a pro-inflammatory protein that could play an important part in improving current and future therapeutics for the herpes virus.

29 Oct 2019

Gut microbiome altered by burn injury and influenced by fluid resuscitation, study shows

Major burns lead to changes in the gastrointestinal tract bacteria, and these alterations of the gut microbiome are influenced by resuscitation with intravenous (IV) fluids, according to animal studies reported in SHOCK: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, Official Journal of theShockSociety. The journal is published in the Lippincott portfolio by Wolters Kluwer.

25 Oct 2019

New way to detect and attack cancer cells using solar technology

Scientific breakthroughs don't always happen in labs. For Sophia and Richard Lunt, Michigan State University researchers, many of their breakthroughs happen during neighborhood walks.

25 Oct 2019

Phase 2 clinical trial of CAR T-cell therapy starts at Atlantic Health System

Atlantic Health System is treating patients in a new Phase 2 clinical trial of CAR T-cell therapy at Morristown Medical Center. A select number of sites across the U.S. are involved in this study, which is done on an outpatient basis.

25 Oct 2019

Therapeutics News and Research

Study: Checkpoint inhibitor prolongs survival in patients with head and neck cancers

UI scientists are developing new delivery tools for gene editing

Risky strategy allows malaria parasite to quickly respond to unpredictable changes

Doctors report first death from fecal microbiota transplant

Researchers identify genes linked to most severe symptoms of multiple sclerosis

Robotic-assisted surgery can improve longevity of knee replacement

Education may erase risk of cognitive decline linked to APOE e4 gene in black people

New study finds racial/ethnic variation in discharge destination after knee replacement surgery

CEM enters into a definitive agreement to purchase key assets of Intavis Bioanalytical Instruments

New collaborative effort focuses on therapeutic research for CDKL5 Deficiency Disorder

DNA sequences encode information in many different ways

Poverty, race have no impact on total knee replacement revision or failure

Rutgers selected to speed up development of biomedical health technologies

Researchers make progress toward gene-based strategies to treat inherited neurometabolic diseases

First effective noninvasive method for diagnosing early-stage liver diseases

Femtogenix announces new data on ADCs containing reduced potency payloads in solid tumor models

Pro-inflammatory protein could play key role in protecting against herpes virus

Gut microbiome altered by burn injury and influenced by fluid resuscitation, study shows

New way to detect and attack cancer cells using solar technology

Phase 2 clinical trial of CAR T-cell therapy starts at Atlantic Health System

Advancing therapeutic biopolymer development eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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