Immune System News and Research

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Interfering RNA nanoparticles could be a potential COVID-19 therapy

Study shows lipid nanoparticle-based siRNA is potent in suppressing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the causative agent of coronavirus disease 2019 (COVID-19) – in cells as well as in mice models.

21 Apr 2021

Research offers new insights on the significance of hyperinflammation following SARS-COV-2 infection

Severe cases of COVID-19 can involve extensive inflammation in the body, and clinicians have wondered if this state is similar to what are called cytokine storm syndromes, in which the immune system produces too many inflammatory signals that can sometimes lead to organ failure and death.

21 Apr 2021

Changes to infant gut bacteria and food allergies are linked to C-section birth, ethnicity

Researchers have found a causal link between caesarean section birth, low intestinal microbiota and peanut sensitivity in infants, and they report the effect is more pronounced in children of Asian descent than others, in a recently published paper in the journal of the American Gastroenterological Association.

21 Apr 2021

Researchers identify differences in immune response in asymptomatic versus severe COVID-19 cases

The largest study of its type in the UK has identified differences in the immune response to COVID-19, between people with no symptoms, compared to those suffering a more serious reaction to the virus.

21 Apr 2021

Study identifies how SARS-CoV-2 enters and infects the brain

A recent preclinical study led by Anja Kipar of the University of Zurich and the University of Liverpool found evidence of the virus infecting and eventually provoking cell death in microglia and immune cells — but not neurons. The viral-induced apoptosis in these brain cells may explain why some long-haulers experience ‘brain fog’ months after recovery.

21 Apr 2021

Blood-brain barrier and its effect on the immune system play a role in schizophrenia

Like a stern bodyguard for the central nervous sytem, the blood-brain barrier keeps out anything that could lead to disease and dangerous inflammation--at least when all is functioning normally.

21 Apr 2021

Organ tissues become increasingly immune throughout life, new study suggests

University of Minnesota Medical School researchers have offered new ways to think about the immune system thanks to a recent study published in Nature.

20 Apr 2021

Genethon announces dosing of first patient at pediatric clinical trial platform for neuromuscular diseases

A first participant was dosed at I-Motion, the pediatric clinical trial platform for neuromuscular diseases located at Trousseau hospital in Paris, as part of the gene therapy trial in Duchenne muscular dystrophy (DMD) conducted by Genethon.

20 Apr 2021

Overgrowth of gut yeast in newborns associated with increased risk of asthma

An overgrowth of yeast in the gut within the first few months of life may cause changes to the immune system that increase the risk of asthma later on, shows a study published today in eLife.

20 Apr 2021

Study examines SARS-CoV-2 seropositivity in healthy young adults and risk of reinfection

New research has been published in The Lancet Respiratory Medicine, which focuses on evaluating the effect of SARS-CoV-2 seropositivity on the possibility of developing SARS-CoV-2 infection in a young and healthy population. This study is based on the longitudinal prospective cohort study that involves the COVID-19 Health Action Response for Marines (CHARM).

20 Apr 2021

Could virosome-based nanovaccines be a promising new approach to preventing viral diseases?

A recent review in the International Journal of Biological Macromolecules provides a novel overview of 'virosome'-based nanovaccine production, its properties, and its application in viral diseases, emphasizing its importance in SARS-CoV-2 vaccine discovery.

20 Apr 2021

Gut's immune response in COVID-19 patients may not provide adequate protection to other organs

Our guts may not provide long-lasting systemic immunity from COVID-19, which is where immune cells circulate through the body to provide protection to other organs, finds a new study published in Frontiers in Immunology.

20 Apr 2021

Scientists receive NIH grant to develop an adjuvant vaccine for opioid use disorder

Opioid addicts wage a daily war within over whether or not to use a drug whose side effect can be death. If those same addicts, however, had the choice to take an opioid vaccine once or twice a year, their internal struggle could be over.

20 Apr 2021

Yale scientists uncover common mechanism that promotes autoimmune diseases and blood cancers

In a study by Yale Cancer Center, researchers report on the discovery of a common mechanism that promotes both autoimmune diseases and blood cancers, including the blood diseases Acute Lymphoblastic Leukemia (ALL), Chronic Lymphocytic Leukemia (CLL) and Mantle Cell Lymphoma (MCL).

19 Apr 2021

COVID-19 pandemic has created major changes in delivery of MS care

A survey of U.S. multiple sclerosis, or MS, specialist clinicians reveals the COVID-19 pandemic has created major changes in how they deliver care.

19 Apr 2021

Researchers decipher the molecular underpinning of exceptional responses in glioblastoma patients

Despite access to some of the best possible medical care in the world, Senators John McCain and Edward Kennedy both died within 18 months of their diagnosis of glioblastoma, an aggressive form of brain cancer.

19 Apr 2021

One dose of mRNA vaccine may be sufficient for individuals previously infected with SARS-CoV-2

A recent scientific report from Israel shows how healthcare workers previously infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) present with higher Immunoglobulin G (IgG) titers after receiving one dose of Pfizer–BioNTech COVID-19 vaccine in comparison to their fully vaccinated, never-infected counterparts. Conversely, the occurrence of post-vaccination infection does not increase IgG titers.

19 Apr 2021

Research team identifies new factor in the development of psoriasis

Psoriasis is a common inflammatory skin condition. The underlying genetic factors have not yet been sufficiently researched.

19 Apr 2021

Study sheds new light on the ability of pancreatic cancer cells to metastasize

With an overall survival rate of 9% for those diagnosed, pancreatic cancer remains exceedingly difficult to treat. However, the patient's primary tumor typically isn't what leads to death - it is the cancer's ability to evade detection and metastasize to other organs.

19 Apr 2021

New COVID-19 vaccine could provide protection against existing and future strains of coronaviruses

A COVID-19 vaccine that could provide protection against existing and future strains of the COVID-19 coronavirus, and other coronaviruses, and cost about $1 a dose has shown promising results in early animal testing.

19 Apr 2021

Immune System News and Research

Interfering RNA nanoparticles could be a potential COVID-19 therapy

Research offers new insights on the significance of hyperinflammation following SARS-COV-2 infection

Changes to infant gut bacteria and food allergies are linked to C-section birth, ethnicity

Researchers identify differences in immune response in asymptomatic versus severe COVID-19 cases

Study identifies how SARS-CoV-2 enters and infects the brain

Blood-brain barrier and its effect on the immune system play a role in schizophrenia

Organ tissues become increasingly immune throughout life, new study suggests

Genethon announces dosing of first patient at pediatric clinical trial platform for neuromuscular diseases

Overgrowth of gut yeast in newborns associated with increased risk of asthma

Study examines SARS-CoV-2 seropositivity in healthy young adults and risk of reinfection

Could virosome-based nanovaccines be a promising new approach to preventing viral diseases?

Gut's immune response in COVID-19 patients may not provide adequate protection to other organs

Scientists receive NIH grant to develop an adjuvant vaccine for opioid use disorder

Yale scientists uncover common mechanism that promotes autoimmune diseases and blood cancers

COVID-19 pandemic has created major changes in delivery of MS care

Researchers decipher the molecular underpinning of exceptional responses in glioblastoma patients

One dose of mRNA vaccine may be sufficient for individuals previously infected with SARS-CoV-2

Research team identifies new factor in the development of psoriasis

Study sheds new light on the ability of pancreatic cancer cells to metastasize

New COVID-19 vaccine could provide protection against existing and future strains of coronaviruses

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