Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Cosmetics may contain chemicals that raise risk of obesity and diabetes

Scientists found that those who were exposed to phthalates, colourless man-made substances included in a variety of common consumer products, were more prone to weight gain. And subjects with even 'modest' levels of the substance in their bloodstream were twice as likely to develop diabetes.

16 Apr 2012

High blood sugar in combination with high insulin levels causes fatty deposits in the heart

The impaired substrate metabolism of diabetes patients is often expressed in an increase in fatty deposits in the cells of the heart muscle. Until now, the exact cause of this was unknown. Now, researchers at the MedUni Vienna in the Division of Endocrinology and Metabolism of MedUni Vienna in cooperation with the MR Centre of Excellence Vienna have shown that high blood sugar in combination with high levels of insulin - not an influx of fats - results in such deposits within a few hours.

16 Apr 2012

Link between phthalates and risk of diabetes among seniors

There is a connection between phthalates found in cosmetics and plastics and the risk of developing diabetes among seniors. Even at a modest increase in circulating phthalate levels, the risk of diabetes is doubled. This conclusion is drawn by researchers at Uppsala University in a study published in the journal Diabetes Care.

16 Apr 2012

UM hosts symposium on next generation characterization tools for therapeutic proteins

In a concerted effort to boost regional collaboration on developing new protein drug and diagnostics, the University of Maryland (UM) School of Pharmacy has hosted the first Interdisciplinary Symposium on Next Generation Characterization Tools for Therapeutic Proteins.

16 Apr 2012

UVA engineer and biologist named recipients of Hartwell Individual Biomedical Research Awards

University of Virginia engineer Silvia Salinas Blemker and biologist Christopher Deppmann have been named recipients of 2011 Hartwell Individual Biomedical Research Awards, which provide $100,000 in annual research support for three years to each awardee.

16 Apr 2012

Targeting glucagon's sweetening effect may treat type II diabetes

Maintaining the right level of sugar in the blood is the responsibility not only of insulin, which removes glucose, but also of a hormone called glucagon, which adds glucose.

16 Apr 2012

Positive top-line results from Biodel’s Phase 1 trial of two RHI-based formulations

Biodel Inc. today announced positive top-line results from a Phase 1 clinical trial of its product candidates, BIOD-123 and BIOD-125 -- two proprietary ultra-rapid-acting formulations of recombinant human insulin.

16 Apr 2012

Inadequate sleep linked to higher diabetes risk

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12 Apr 2012

Too little sleep, inconsistent sleep patterns increase risk of diabetes and obesity

A study by researchers at Brigham and Women's Hospital (BWH) reinforces the finding that too little sleep or sleep patterns that are inconsistent with our body's "internal biological clock" may lead to increased risk of diabetes and obesity.

12 Apr 2012

Overweight moms with moderately high blood sugar raise health risk

Pregnant women who are overweight with moderately elevated blood sugar never set off any alarms for their physicians. The big concern was for women who were obese or who had gestational diabetes because those conditions are known to cause a host of health risks to the mom and baby.

12 Apr 2012

Transcription factors do not act like an 'on-off' switch

A UNC-led team of scientists has now shown that transcription factors don't act like an 'on-off' switch, but instead can exhibit much more complex binding behavior.

12 Apr 2012

Study reveals difficulties in self-management of diabetes

A new study from researchers at Queen Mary, University of London reveals the many difficulties faced by people with diabetes in self-managing their disease.

11 Apr 2012

Women less likely to get at least 30 minutes of exercise per day

A national study shows that women are less likely than men to get at least 30 minutes of exercise per day, resulting in greater odds of developing metabolic syndrome - a risky and increasingly prevalent condition related to obesity.

11 Apr 2012

First study to examine links between neurodevelopmental disorders and maternal metabolic conditions

A major study of the relationships between maternal metabolic conditions and the risk that a child will be born with a neurodevelopmental disorder has found strong links between maternal diabetes and obesity and the likelihood of having a child with autism or another developmental disability.

9 Apr 2012

Researchers discover two molecules that control liver glucose production

In their extraordinary quest to decode human metabolism, researchers at the Salk Institute for Biological Studies have discovered a pair of molecules that regulates the liver's production of glucose---- the simple sugar that is the source of energy in human cells and the central player in diabetes.

9 Apr 2012

Researchers understand TG paradox in people of African descent

In most people, high blood levels of the fat known as triglycerides are an early warning sign of type 2 diabetes and metabolic syndrome, but in people of African descent these dangerous health conditions may go undiagnosed because triglyceride levels are not at the level used to diagnose metabolic syndrome (>150 mg/dL). This is known as the "TG (or lipid) paradox."

6 Apr 2012

Researchers generate endodermal progenitor cells for future diabetes treatments

Researchers have generated a new type of human stem cell that can develop into numerous types of specialized cells, including functioning pancreatic beta cells that produce insulin. Called endodermal progenitor (EP) cells, the new cells show two important advantages over embryonic stem cells and induced pluripotent stem cells: they do not form tumors when transplanted into animals, and they can form functional pancreatic beta cells in the laboratory.

6 Apr 2012

FuelCo campaign raises $20,000 to benefit cure-focused work of DRI

In six short weeks, FuelCo, which operates various retail and convenience stores throughout Connecticut and New York, sold $20,000 worth of scannable cards recently to benefit the cure-focused work of the Diabetes Research Institute.

6 Apr 2012

Low glycemic index food may help prevent high blood sugar

Eating foods at breakfast that have a low glycemic index may help prevent a spike in blood sugar throughout the morning and after the next meal of the day, researchers said at the Institute of Food Technologists' Wellness 12 meeting.

5 Apr 2012

Piceatannol blocks preadipocytes’ ability to develop and grow

A compound found in red wine, grapes and other fruits, and similar in structure to resveratrol, is able to block cellular processes that allow fat cells to develop, opening a door to a potential method to control obesity, according to a Purdue University study.

5 Apr 2012