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Tobacco control must be highest priority in national cancer control plan, says report

The highest priority in a national cancer control plan must be expansion of tobacco control--the intervention with the largest potential health benefits--according to a new American Cancer Society report, the second in a series of articles that together inform priorities for a comprehensive cancer control plan.

11 Oct 2018

Using nanotechnology to fight dementia

In the human brain, nerve cells - so-called neurons - care for the transmission of electrical signals. They form the functional component responsible for sensations, stimuli and memories. In the presence of dementia, there is an adsorption of proteins outside the neurons, which then leads to the death of the neuronal cells. How to prevent the death of neurons is still the subject of scientific research today.

10 Oct 2018

Prevalence of virulent K. pneumoniae strains among neonates is higher than was previously thought

The research was conducted by Kazan Federal University, Kazan State Medical University, City Clinical Children's Hospital N 1, and Republican Clinical Infectious Diseases Hospital.

10 Oct 2018

A new promising method for treating pancreatic cancer

A new approach to treating pancreatic cancer using 'educated killer cells' has shown promise, according to early research by Queen Mary University of London.

10 Oct 2018

University of Houston biologist explores therapeutic targets to prevent atherosclerosis

University of Houston biologist Michihisa Umetani, having discovered that a certain protein partnership acts to rapidly signal molecules inside blood vessels that danger is upon them, has been awarded $382,500 by the National Institutes of Health.

10 Oct 2018

Binge drinking history makes male and female mice react differently to stress, study shows

Researchers with the Veterans Affairs Portland Health Care System and Oregon Health & Sciences University found that a history of binge drinking made male and female mice react differently to traumatic stress.

10 Oct 2018

New pre-clinical research shows utility of mRNA platform to treat rare metabolic disorders

An mRNA platform that can express therapeutic levels of protein in liver tissue could be used to treat patients with rare metabolic disorders.

9 Oct 2018

King's College researchers awarded £2.3 million for new trial to treat liver disease

Dr Mark McPhail from the Department of Inflammation Biology, School of Immunology & Microbial Sciences and Dr Vishal Patel from the Institute of Liver Studies at King's College Hospital have been awarded £2.3 million by the National Institute of Health Research Health Technology Assessment to lead a new UK wide multi-centre trial to treat liver disease.

9 Oct 2018

New genome editing tool used to heal genetic disease

Parents of newborns may be familiar with the metabolic disorder phenylketonuria: in Switzerland, all newborn babies are screened for this genetic disease.

8 Oct 2018

Researchers use CRISPR-Cas9 to prevent congenital disease in utero

Researchers have successfully used prenatal gene editing (CRISPR-Cas9) to prevent a fatal metabolic disorder in an animal model.

8 Oct 2018

Scientists discover new molecular pathway that controls colorectal cancer development

Scientists from the Cancer Science Institute of Singapore at the National University of Singapore have discovered a new molecular pathway that controls colorectal cancer development, and their exciting findings open new therapeutic opportunities.

8 Oct 2018

A glass of wine a day may raise the risk of an early death

Even moderate drinking (four drinks or more per week) can increase the risk of cancer and an early death, according to a new study.

5 Oct 2018

Study shows possibility of using PET imaging to manage chronic liver diseases

While liver biopsies are powerful and reliable, they are also invasive, painful, limited and subject to complications. These effects may soon be a thing of the past for some patients thanks to new research showing PET imaging with the 18F-FAC radiotracer can be used as a non-invasive substitute. The study is featured in the October issue of The Journal of Nuclear Medicine.

5 Oct 2018

Lilly, Boehringer Ingelheim present full results of cardiovascular outcome trial, CARMELINA

Boehringer Ingelheim and Eli Lilly and Company today presented the full results of the long-term cardiovascular outcome trial, CARMELINA®, which studied the impact of Trajenta® (linagliptin) on cardiovascular and kidney safety in adults with type 2 diabetes at high risk for heart and/or kidney disease.

5 Oct 2018

Tarragon and bitter melon supplements may be less helpful for women than men

Russian tarragon and bitter melon supplements may be less helpful for women than men when it comes to combating metabolic syndrome, whose symptoms include high blood sugar, high blood pressure and excess fat around the waist.

5 Oct 2018

New report provides overview of cancer risk among U.S. Hispanics/Latinos

The cancer burden in Puerto Rico, a U.S. territory with a 99% Hispanic population, is substantially different from that of Hispanics in the continental U.S., according to Cancer Statistics for Hispanics/Latinos, 2018.

4 Oct 2018

Alnylam announces positive results from Phase 1/2 study of lumasiran for treating primary hyperoxaluria-1

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today updated positive results from its Phase 1/2 clinical study of lumasiran, an investigational, subcutaneously administered RNAi therapeutic targeting glycolate oxidase for the treatment of primary hyperoxaluria type 1.

4 Oct 2018

Wits doctors transplant liver from HIV positive mother to her child with end-stage liver disease

This was the ethical dilemma faced by doctors at Wits Donald Gordon Medical Centre to save a child's life.

4 Oct 2018

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that it has submitted a Clinical Trial Authorization application to the Medicines and Healthcare products Regulatory Agency to initiate a Phase 1/2 study of ALN-AAT02, an investigational RNAi therapeutic targeting alpha-1 antitrypsin for the treatment of AAT deficiency-associated liver disease.

3 Oct 2018

Hopkins gastroenterologists use endoscopic procedure to deliver therapeutic genes to the liver

Fixing or replacing faulty genes has emerged as a key to unlocking cures for numerous devastating diseases. But if the new, engineered genes can't find their way into the patient's genomic sequence, they won't help.

3 Oct 2018

Liver News and Research

Tobacco control must be highest priority in national cancer control plan, says report

Using nanotechnology to fight dementia

Prevalence of virulent K. pneumoniae strains among neonates is higher than was previously thought

A new promising method for treating pancreatic cancer

University of Houston biologist explores therapeutic targets to prevent atherosclerosis

Binge drinking history makes male and female mice react differently to stress, study shows

New pre-clinical research shows utility of mRNA platform to treat rare metabolic disorders

King's College researchers awarded £2.3 million for new trial to treat liver disease

New genome editing tool used to heal genetic disease

Researchers use CRISPR-Cas9 to prevent congenital disease in utero

Scientists discover new molecular pathway that controls colorectal cancer development

A glass of wine a day may raise the risk of an early death

Study shows possibility of using PET imaging to manage chronic liver diseases

Lilly, Boehringer Ingelheim present full results of cardiovascular outcome trial, CARMELINA

Tarragon and bitter melon supplements may be less helpful for women than men

New report provides overview of cancer risk among U.S. Hispanics/Latinos

Alnylam announces positive results from Phase 1/2 study of lumasiran for treating primary hyperoxaluria-1

Wits doctors transplant liver from HIV positive mother to her child with end-stage liver disease

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

Hopkins gastroenterologists use endoscopic procedure to deliver therapeutic genes to the liver

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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