Immune System News and Research

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Researchers develop computational model to predict changes in SARS-CoV-2’s viral fitness

Two researchers from the Université Libre de Bruxelles in Belgium, Fabrizio Pucci and Marianne Rooman, recently built a simplified computational model, called SpikePro, to predict the SARS-CoV-2 fitness from the amino acid sequence and structure of the spike protein. This study focuses on the spike protein’s stability and the binding affinity to the host receptor.

19 Apr 2021

Antibodies may not inhibit SARS-COV-2 variants from mink

It has been known for about a year that minks can become infected with SARS-CoV-2. The virus had been transmitted from humans to farmed mink and mutated in infected animals.

19 Apr 2021

Obesity, hypertension and smoking linked to lower vaccine-induced antibody production against SARS-CoV-2

In a recent study posted to the medRxiv preprint server, a research group from Italy has demonstrated that the antibody response can be blunted in subjects with certain risk factors shortly after the second dose of mRNA vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Apr 2021

FDA revokes EUA for monoclonal antibody therapy bamlanivimab to treat patients with COVID-19

Today, the U.S. Food and Drug Administration revoked the emergency use authorization (EUA) that allowed for the investigational monoclonal antibody therapy bamlanivimab, when administered alone, to be used for the treatment of mild-to-moderate COVID-19 in adults and certain pediatric patients.

17 Apr 2021

The shock and reality of catching Covid after being vaccinated

Robin Hauser, a pediatrician in Tampa, Fla., got covid in February. What separates her from the vast majority of the tens of millions of other Americans who have come down with the virus is this: She got sick seven weeks after her second dose of the Pfizer-BioNTech vaccine.

17 Apr 2021

Studies suggest mRNA COVID-19 vaccine may have reduced efficacy in patients with blood cancer

Two new studies published in Blood suggest that the mRNA COVID-19 vaccine may have reduced efficacy in individuals with chronic lymphocytic leukemia (CLL) and multiple myeloma, two types of blood cancer.

17 Apr 2021

Novel CRISPR-based technology may lead to powerful epigenetic therapies

Scientists have figured out how to modify CRISPR's basic architecture to extend its reach beyond the genome and into what's known as the epigenome -- proteins and small molecules that latch onto DNA and control when and where genes are switched on or off.

17 Apr 2021

Candidate coronavirus vaccines show promising results in early animal testing

A candidate vaccine that could provide protection against the COVID-19 virus and other coronaviruses has shown promising results in early animal testing.

17 Apr 2021

Exposure to silica dust at work may increase risk of autoimmune rheumatic diseases

If you are exposed to silica (quartz) dust at work - e.g. from working with concrete and granite - you have a greater risk of certain types of rheumatic disease.

17 Apr 2021

FDA approves immunotherapy for first-line treatment of advanced gastric cancer

Today, the U.S. Food and Drug Administration approved Opdivo (nivolumab), in combination with certain types of chemotherapy, for the initial treatment of patients with advanced or metastatic gastric cancer, gastroesophageal junction cancer and esophageal adenocarcinoma.

16 Apr 2021

Mysterious ailment, mysterious relief: Vaccines help some Covid long haulers

An estimated 10% to 30% of people who get Covid-19 suffer from lingering symptoms of the disease, or what’s known as “long Covid.”

16 Apr 2021

Cell receptor neuropilin-1 offers a promising anti-tumor strategy

Cancer is an insidious disease that, despite being around for centuries, is still very difficult to diagnose and treat. Thus, cancer has been the focus much research in the biomedical fields.

16 Apr 2021

Study: Norovirus clusters are resistant to detergent and ultraviolet disinfection

Clusters of a virus known to cause stomach flu are resistant to detergent and ultraviolet disinfection, according to new research co-led by Danmeng Shuai, Ph.D., an associate professor of civil and environmental engineering at the George Washington University and Nihal Altan-Bonnet, Ph.D., a senior investigator and the head of the Laboratory of Host-Pathogen Dynamics at the National Heart, Lung, and Blood Institute, part of the National Institutes of Health.

16 Apr 2021

More SARS-CoV-2 variants have emerged from immunocompromised hosts, shows research

A number of SARS-CoV-2 variants have emerged from immunocompromised hosts, research has identified. It is thought that variants of concern - including B.1.1.7, a variant first identified in Kent - were a result of long-term infection in people with a weakened immune system.

16 Apr 2021

COVID-19 vaccine INO-4800 shows efficacy against SARS-CoV-2 variants

Researchers in the United States have demonstrated the efficacy of the vaccine INO-4800 against variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

15 Apr 2021

CU researcher receives NIH grant to analyze the link between gut microbiome and osteoarthritis

Osteoarthritis affects the joints, but according to researcher Michael Zuscik, PhD, it may start in the gut.

15 Apr 2021

Study may lead to new therapies for patients suffering from Duchenne muscular dystrophy

A new study, led by the University of California, Irvine (UCI), reveals how chronic inflammation promotes muscle fibrosis, which could inform the development of new therapies for patients suffering from Duchenne muscular dystrophy (DMD), a fatal muscle disease.

15 Apr 2021

Immune System News and Research

Researchers develop computational model to predict changes in SARS-CoV-2’s viral fitness

Antibodies may not inhibit SARS-COV-2 variants from mink

Obesity, hypertension and smoking linked to lower vaccine-induced antibody production against SARS-CoV-2

FDA revokes EUA for monoclonal antibody therapy bamlanivimab to treat patients with COVID-19

The shock and reality of catching Covid after being vaccinated

Studies suggest mRNA COVID-19 vaccine may have reduced efficacy in patients with blood cancer

Novel CRISPR-based technology may lead to powerful epigenetic therapies

Candidate coronavirus vaccines show promising results in early animal testing

Exposure to silica dust at work may increase risk of autoimmune rheumatic diseases

FDA approves immunotherapy for first-line treatment of advanced gastric cancer

Mysterious ailment, mysterious relief: Vaccines help some Covid long haulers

Cell receptor neuropilin-1 offers a promising anti-tumor strategy

Study: Norovirus clusters are resistant to detergent and ultraviolet disinfection

More SARS-CoV-2 variants have emerged from immunocompromised hosts, shows research

COVID-19 vaccine INO-4800 shows efficacy against SARS-CoV-2 variants

CU researcher receives NIH grant to analyze the link between gut microbiome and osteoarthritis

Study may lead to new therapies for patients suffering from Duchenne muscular dystrophy

Population-based study shows the persistence of neutralizing antibodies against coronavirus

Self-assembling nanofibers can help limit damage caused by inflammatory diseases

Ebola virus's key protein uses molecular triggers in the human cell to change shape

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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