Atherosclerosis News and Research

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Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.

Scientists determine trajectory and pathophysiology of post-COVID-19 syndrome

A new study utilizes multisystem imaging, along with biomarker analysis, to better understand the pathogenesis of COVID-19.

30 May 2022

The role of pyroptosis in COVID-19

Researchers investigate the mechanisms by which SARS-CoV-2 induces NLRP3 inflammasome formation leading to pyroptosis.

25 May 2022

Novel ultrasound-assisted laser technique removes arterial plaque safely and efficiently

Atherosclerosis, a buildup of plaque, can lead to heart disease, artery disease, and chronic kidney disease and is traditionally treated by inserting and inflating a balloon to expand the artery.

24 May 2022

APOB-specific T cells may contribute to inflammation and further the progression of atherosclerosis

Preventing atherosclerosis, the underlying cause of heart disease, means scientists need to understand how immune cells drive inflammation in the arteries.

20 May 2022

Study demonstrates how the transcription factor C/EBPβ can positively influence fat storage

The chronic nutritional and metabolic disease of obesity is characterized by an excessive increase in body fat and its accumulation in tissues.

20 May 2022

Consumption of cranberries could improve memory, ward off dementia, and lower 'bad' cholesterol

Adding cranberries to your diet could help improve memory and brain function, and lower ‘bad’ cholesterol – according to new research from the University of East Anglia (UK).

18 May 2022

New mouse model shows the connection between stress, depression and cardiovascular disease risk

Results from a new mouse model may aid in understanding how depression and prolonged and severe stress increase the risk of cardiovascular disease, according to preliminary research presented at the American Heart Association's Vascular Discovery: From Genes to Medicine Scientific Sessions 2022.

13 May 2022

Hormonal shift during menopause changes women’s blood metabolite profile

In midlife, the risk of cardiometabolic diseases increases in women more rapidly than in men. A study performed at the Faculty of Sport and Health Sciences of the University of Jyväskylä shows that changes in blood metabolite profile accompany the shift in sex hormone levels during menopause.

13 May 2022

New implantable device enables wireless real-time monitoring of hemodynamics

Vascular diseases are public enemy number one: the leading killers worldwide, accounting for nearly a third of all human deaths on the planet.

12 May 2022

Novel genetic mapping study traces links between DNA variations and blood proteins

A new genetic mapping study led by researchers at the Johns Hopkins Bloomberg School of Public Health traces links between DNA variations and thousands of blood proteins in two large and distinct populations. The results should help researchers better understand the molecular causes of diseases and identify proteins that could be targeted to treat these diseases.

3 May 2022

Study explores sex-driven differences in individualized clinical management of Alzheimer’s disease risk

A new study demonstrated how individualized clinical management of Alzheimer's disease risk was viable in a clinical outpatient setting.

29 Apr 2022

Aspirin for non-obstructive coronary artery disease does not reduce major cardiovascular events

Aspirin therapy, as opposed to statin use, for non-obstructive coronary artery disease does not reduce major cardiovascular events, according to a new study published in the journal Radiology: Cardiothoracic Imaging.

28 Apr 2022

Penn scientists discover how one inflammatory disorder increases susceptibility to another

The immune system remembers. Often this memory, primed by past encounters with threats like bacteria or viruses, is an asset. But when that memory is sparked by internal drivers, like chronic inflammation, it can prove detrimental, perpetuating a misguided immune response.

27 Apr 2022

Research shows existence of a link between atherosclerotic plaques and the central nervous system

A new research shows the existence of a connection between atherosclerotic plaques and the central nervous system.

27 Apr 2022

Study evaluates the use of a diagnostic code for Long COVID

Researchers evaluated the use of U09.9, a CD-10-CM code described as 'Post coronavirus disease 2019 (COVID-19) condition, unspecified' for post-acute COVID-19 sequelae (long COVID).

21 Apr 2022

About one in four adults has a liver condition that is a risk factor for heart disease

It is estimated that about one in four adults worldwide has a liver condition that is a risk factor for heart disease, according to a new American Heart Association scientific statement published today in the Association's peer-reviewed journal Arteriosclerosis, Thrombosis, and Vascular Biology.

14 Apr 2022

Dietary influences on long COVID in children

A new study discusses possible mechanisms of long COVID in children and how they might relate to their dietary intake of important vitamins and elements.

13 Apr 2022

Addition of alirocumab to high-intensity statin treatment reduces key measures of plaque vulnerability

Compared with a placebo, the addition of the injectable cholesterol-lowering drug alirocumab to high-intensity statin treatment in patients who have had a heart attack resulted in twofold greater reductions in three key measures of plaque vulnerability that signal risk for future cardiac events, according to research presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Good hydration may be linked with reduced risk of heart failure

Staying well-hydrated may be associated with a reduced risk for developing heart failure, according to researchers at the National Institutes of Health.

29 Mar 2022

Deleting a protein could prevent heart attacks and strokes in humans

Macrophages travel through our arteries, gobbling fat the way Pac-man gobbled ghosts. But fat-filled macrophages can narrow blood vessels and cause heart disease.

28 Mar 2022