Genetic Engineering News and Research

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Star-shaped brain cells impact the length and depth of sleep in mice

For something we spend one-third of our lives doing, we still understand remarkably little about how sleep works -- for example, why can some people sleep deeply through any disturbance, while others regularly toss and turn for hours each night? And why do we all seem to need a different amount of sleep to feel rested?

22 Mar 2021

Genetic engineering strategy dramatically reduces tau levels in Alzheimer's animal model

Researchers have used a genetic engineering strategy to dramatically reduce levels of tau--a key protein that accumulates and becomes tangled in the brain during the development of Alzheimer's disease--in an animal model of the condition.

21 Mar 2021

Developing a COVID-19 vaccine using inactivated E. coli

A team of researchers inactivated whole-cell E.coli with a reduced genome and utilized this to express coronavirus-specific fusion peptides, demonstrating a potent anamnestic response.

19 Mar 2021

Study explores how CAR T immunotherapy could be used to treat solid tumors

A study recently published in the journal Science looked into how CAR T immunotherapy could be used to treat solid tumors in addition to leukemias. The programming of CAR T cells opens avenues for applying cell therapies to, for example, breast cancer or ovarian cancer in the future.

18 Mar 2021

Novel cancer-fighting gene therapy enters phase I clinical trial

Researchers from the MDC and Charité have developed a new gene therapy based around a special T-cell receptor that helps the immune system effectively recognize and fight cancer cells.

18 Mar 2021

HPSE protein found to be a key regulator of cells’ innate defense mechanisms

Researchers at the University of Illinois Chicago have discovered that heparanase, HPSE, a poorly understood protein, is a key regulator of cells' innate defense mechanisms.

15 Mar 2021

New book explains concept and knowledge maps about biochemical compounds

Mind Maps in Biochemistry presents a series of concept and knowledge maps about biochemical compounds, systems and techniques.

12 Mar 2021

New book explains concept and knowledge maps about biochemical compounds

Mind Maps in Biochemistry presents a series of concept and knowledge maps about biochemical compounds, systems and techniques.

12 Mar 2021

New approach could treat infertility caused by abnormal GnRH secretion

Reports suggest that at least 25% of ovarian disorders are due to dysfunction of the brain mechanism in the hypothalamus that controls the gonadotropin-releasing hormone (GnRH), which is a molecule that governs the reproductive function in men and women by regulating the release of a range of reproductive hormones into the body, particularly gonadotropins, from the pituitary gland, which is located underneath the brain.

12 Mar 2021

Unbalanced progesterone may cause preterm or prolonged labor in some pregnant women

New research by the National Institutes of Health found that unbalanced progesterone signals may cause some pregnant women to experience preterm labor or prolonged labor.

11 Mar 2021

Study opens the door to new possibilities targeting telomeres to help treat cancer

The Telomeres and Telomerase Group led by Maria A. Blasco at the Spanish National Cancer Research Centre continues to make progress in unraveling the role that telomeres -the ends of chromosomes that are responsible for cellular aging as they shorten- play in cancer.

10 Mar 2021

Research reveals link between proteins causing Alzheimer's disease and age-related sight loss

Newly published research has revealed a close link between proteins associated with Alzheimer's disease and age-related sight loss.

10 Mar 2021

New SARS-CoV-2 vaccine candidate produces strong immune response, prevents SARS-CoV-2 infection

A new SARS-CoV-2 vaccine candidate, developed by giving a key protein's gene a ride into the body while encased in a measles vaccine, has been shown to produce a strong immune response and prevent SARS-CoV-2 infection and lung disease in multiple animal studies.

10 Mar 2021

Phase 2 clinical trial is now open at Columbia to test gene therapy for dry macular degeneration

A phase 2 clinical trial is underway at Columbia University and NewYork-Presbyterian to test an investigational gene therapy for dry age-related macular degeneration, a progressive, chronic eye disease with no cure and a leading cause of blindness in the United States.

9 Mar 2021

Bruker announces new results in deep, unbiased plasma proteomics, PaSER 1.1 software and new cross-linking consumables at US HUPO 2021

At the virtual 17th US HUPO Conference (US HUPO 2021), Bruker Corporation (Nasdaq: BRKR) today announces progress with several collaborations in deep, unbiased plasma proteomics, leveraging the speed, sensitivity and dynamic range of 4D proteomics on timsTOF Pro systems.

From Bruker Daltonics 9 Mar 2021

Self-assembling nanoparticles an effective vaccine candidate for SARS-CoV-2

The currently developed vaccines against SARS-CoV-2 include the RBD in their immunogen. With a similar objective, a new study developed an RBD protein-based vaccine candidate against the SARS-CoV-2, using self-assembling Helicobacter pylori-bullfrog ferritin nanoparticles as an antigen delivery system. The study is published recently in the journal mBio (by the American Society of Microbiology).

8 Mar 2021

New method provides more control over gene drive releases

Powerful new genetic engineering methods have given scientists the potential to revolutionize several sectors of global urgency.

8 Mar 2021

Researchers create new nerve cells, spur recovery after spinal cord injury

Using genetic engineering, researchers at UT Southwestern and Indiana University have reprogrammed scar-forming cells in mouse spinal cords to create new nerve cells, spurring recovery after spinal cord injury.

8 Mar 2021

Cigarette smoke toxicity impacts protective biofilm in the lungs, study finds

Ben-Gurion University of the Negev Researchers (BGU) have found for the first time that cigarette smoke toxicity impacts the protective biofilm in the lungs, particularly concerning when paired with COVID-19 respiratory issues.

3 Mar 2021

Researchers make gametes from xenogenic mouse stem cells

Making gametes such as sperm and eggs from pluripotent stem cells, primitive cells that can make all the tissues, greatly contributes to efficient reproduction of livestock animals and future assisted reproductive medicine. Researchers pave the way to achieve this goal using a body of xenogenic animals.

2 Mar 2021

Genetic Engineering News and Research

Star-shaped brain cells impact the length and depth of sleep in mice

Genetic engineering strategy dramatically reduces tau levels in Alzheimer's animal model

Developing a COVID-19 vaccine using inactivated E. coli

Study explores how CAR T immunotherapy could be used to treat solid tumors

Novel cancer-fighting gene therapy enters phase I clinical trial

HPSE protein found to be a key regulator of cells’ innate defense mechanisms

New book explains concept and knowledge maps about biochemical compounds

New book explains concept and knowledge maps about biochemical compounds

New approach could treat infertility caused by abnormal GnRH secretion

Unbalanced progesterone may cause preterm or prolonged labor in some pregnant women

Study opens the door to new possibilities targeting telomeres to help treat cancer

Research reveals link between proteins causing Alzheimer's disease and age-related sight loss

New SARS-CoV-2 vaccine candidate produces strong immune response, prevents SARS-CoV-2 infection

Phase 2 clinical trial is now open at Columbia to test gene therapy for dry macular degeneration

Bruker announces new results in deep, unbiased plasma proteomics, PaSER 1.1 software and new cross-linking consumables at US HUPO 2021

Self-assembling nanoparticles an effective vaccine candidate for SARS-CoV-2

New method provides more control over gene drive releases

Researchers create new nerve cells, spur recovery after spinal cord injury

Cigarette smoke toxicity impacts protective biofilm in the lungs, study finds

Researchers make gametes from xenogenic mouse stem cells

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