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Nicotine pouch use may be a step toward reducing more dangerous forms of tobacco

As lawmakers and public health experts debate the safety of nicotine pouches, researchers from Rutgers Health found that for now, most adults that use these products also have a history of tobacco use and may be choosing these products as a possible step toward reducing or quitting more dangerous forms of nicotine delivery.

8 Sep 2025

Study identifies a reductive uric acid degradation pathway in anaerobic bacteria

Uric acid builds up in the blood when the body cannot excrete it efficiently, leading to painful gout attacks, kidney stones, and other complications.

8 Sep 2025

How breast milk changes from day to night and why timing matters

Breast milk's hormonal and microbial variations throughout the day may affect infant development, emphasizing the need for synchronized feeding practices.

8 Sep 2025

New method advances RNA velocity analysis with spatial and multi batch integration

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it will be and its function.

5 Sep 2025

Unlocking the secrets of oral bacteria to fight tooth decay

If Wenjun Zhang has her way, no one will ever have to brush or floss again.

5 Sep 2025

Shifts in meal timing predict health and longevity in older adults

As we age, what and how much we eat tends to change. However, how meal timing relates to our health remains less understood. Researchers at Mass General Brigham and their collaborators studied changes to meal timing in older adults and discovered people experience gradual shifts in when they eat meals as they age.

4 Sep 2025

Apple juice has temporary effects on saliva but no lasting damage

A new study led by the University of Portsmouth suggests our saliva is stronger than we thought.

3 Sep 2025

Colorectal cancer identified by its unique microbial fingerprint

Colorectal cancer is unique in having its own microbial 'fingerprint' – according to new research from the University of East Anglia.

3 Sep 2025

Stopping oral anticoagulation reduces risk after successful atrial fibrillation ablation

Discontinuing oral anticoagulation (OAC) therapy resulted in a lower risk of a composite of stroke, systemic embolism or major bleeding than continuing OAC therapy in patients who had successful ablation for atrial fibrillation at least 12 months previously, according to results from a late-breaking trial presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in The Journal of the American Medical Association.

3 Sep 2025

Dental care gaps affect children with sickle cell disease in Michigan

Children with sickle cell disease are more likely to have dental problems - but fewer than half of those covered by Michigan Medicaid got dental care in 2022, according to a new study.

3 Sep 2025

Intravenous cangrelor provides rapid platelet inhibition in cardiogenic shock

Compared with crushed ticagrelor, intravenous cangrelor provided immediate, effective platelet inhibition, with no increase in major bleeding and lower mortality rates in patients with acute myocardial infarction and cardiogenic shock, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

3 Sep 2025

Ablation methods equally effective for drug-resistant paroxysmal atrial fibrillation

Pulsed field ablation did not have superior efficacy to radiofrequency ablation in patients with drug-resistant paroxysmal (intermittent) atrial fibrillation, according to results from a late-breaking trial presented in a Hot Line session today at ESC Congress 2025.

3 Sep 2025

Beetroot juice lowers blood pressure in older adults by reshaping oral bacteria

Dietary nitrate from beetroot juice lowered blood pressure in older adults but not in younger participants in a double-blind crossover trial. The effect was linked to oral microbiome changes, including reduced Prevotella and higher plasma nitrite, without improvements in endothelial function

2 Sep 2025

How raspberry leaf tea reduces insulin surges from table sugar

Trial shows that raspberry leaf tea blunts sucrose-induced glucose and insulin surges, offering a natural strategy for moderating blood sugar without the side effects of pharmaceutical enzyme inhibitors.

2 Sep 2025

Most adults experience dental fear and show interest in virtual fear-treatments

Nearly three out of four adults fear going to the dentist, according to a new study published in the Journal of the American Dental Association.

2 Sep 2025

Breakthrough discovery reveals treatable form of familial mesothelioma

Researchers working independently at the University of Hawaii Cancer Center and the National Cancer Institute have discovered, and validated, a new variant of mesothelioma that may lead to more successful treatments.

2 Sep 2025

Why metformin could protect the brain by rewiring mitochondria

Metformin boosts human oligodendrocyte differentiation and myelination across stem-cell, organoid, and chimera models. The study links these effects to mitochondrial metabolic shifts, supporting its potential as a therapy for multiple sclerosis.

1 Sep 2025

Adding aspirin raises cardiovascular events in high-risk CCS patients on anticoagulants

Adding aspirin increased the risk of cardiovascular events, death and major bleeding in high-risk patients with chronic coronary syndrome (CCS) who had prior stenting and were receiving long-term chronic oral anticoagulation (OAC), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in New England Journal of Medicine.

1 Sep 2025

Tailored risk-based treatment does not improve outcomes in atrial fibrillation

An individually tailored multidimensional risk-based treatment strategy was not associated with improvements in clinical outcomes compared with usual guideline-based care in patients with atrial fibrillation (AF), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

1 Sep 2025

Phase II trial finds zilebesiran lowers systolic blood pressure in patients with uncontrolled hypertension

Among individuals with cardiovascular disease or high cardiovascular risk and uncontrolled hypertension on multiple anti-hypertensive agents, a single subcutaneous dose of zilebesiran 300 mg led to a 5-mmHg reduction in systolic blood pressure at Month 3 compared with placebo, a difference that did not reach statistical significance.

1 Sep 2025

Oral News and Research

Nicotine pouch use may be a step toward reducing more dangerous forms of tobacco

Study identifies a reductive uric acid degradation pathway in anaerobic bacteria

How breast milk changes from day to night and why timing matters

New method advances RNA velocity analysis with spatial and multi batch integration

Unlocking the secrets of oral bacteria to fight tooth decay

Shifts in meal timing predict health and longevity in older adults

Apple juice has temporary effects on saliva but no lasting damage

Colorectal cancer identified by its unique microbial fingerprint

Stopping oral anticoagulation reduces risk after successful atrial fibrillation ablation

Dental care gaps affect children with sickle cell disease in Michigan

Intravenous cangrelor provides rapid platelet inhibition in cardiogenic shock

Ablation methods equally effective for drug-resistant paroxysmal atrial fibrillation

Beetroot juice lowers blood pressure in older adults by reshaping oral bacteria

How raspberry leaf tea reduces insulin surges from table sugar

Most adults experience dental fear and show interest in virtual fear-treatments

Breakthrough discovery reveals treatable form of familial mesothelioma

Why metformin could protect the brain by rewiring mitochondria

Adding aspirin raises cardiovascular events in high-risk CCS patients on anticoagulants

Tailored risk-based treatment does not improve outcomes in atrial fibrillation

Phase II trial finds zilebesiran lowers systolic blood pressure in patients with uncontrolled hypertension

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