Polymerase News and Research

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Study provides valuable insights into the UV susceptibility of SARS-CoV-2 omicron variants

The global outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its new variants has created a need for effective disinfection technologies to protect against harmful pathogens.

27 Jul 2023

Core promoter variation may drive development of triple-negative breast cancer

TNBC is a particularly aggressive subtype of breast cancer, characterized by the absence of three key receptors: estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2).

26 Jul 2023

Can epigenetic changes explain the strong link between age and cancer?

Researchers reported the link between aging, cancer, and epigenomic changes.

26 Jul 2023

Cervical fibroblasts in cervical insufficiency patients show impaired responses to progesterone

The study described in Scientific Reports highlights an impaired response to the hormone progesterone (P4) in cervical fibroblasts from patients with refractory cervical insufficiency (CI).

26 Jul 2023

Tumor-derived GDF-15 suppresses immunotherapy response

Researchers evaluate the impact of tumor-derived GDF-15 on responses to anti-PD-1 immunotherapy.

26 Jul 2023

Targeting chronic endometritis: study reveals potential diagnostic markers

Researchers investigated the gene expression signatures and immune cell involvement in chronic endometritis (CE) for potential diagnostic markers.

25 Jul 2023

Unlocking the secrets of asymptomatic COVID-19 infections: HLA-B*15:01 connection revealed

Researchers describe the findings of the COVID-19 Citizen Science Study.

25 Jul 2023

Comparing COVID-19 symptom burden and quality of life in positive and negative PCR test results

Reports evaluated to what extent symptoms are present before, during, and after a positive SARS-CoV-2 PCR test.

24 Jul 2023

Community COVID-19 disease is associated with increased risks of post-viral-illness, fatigue, embolism, and respiratory conditions

Researchers determined the magnitude of changes in healthcare utilization attributable to severe acute respiratory syndrome coronavirus 2.

24 Jul 2023

Trypsin and anaerobic bacteria boost SARS-CoV-2 Delta variant infectivity: oral hygiene key to prevention

Researchers investigated whether trypsin, a protease, increased SARS-CoV-2 infectivity.

21 Jul 2023

Understanding persistent COVID-19 symptoms: study explores early indicators of long COVID

Researchers investigated early biomarkers of post-acute sequelae of SARS-CoV-2 infection in individuals intensively sampled during the acute phase of COVID-19.

20 Jul 2023

New brain-penetrant agonist shows promise in protecting dopamine neurons for Parkinson's disease treatment

Researchers reported on Nurr1 as a promising therapeutic target for managing Parkinson's disease (PD).

20 Jul 2023

New biosensor could quickly and inexpensively identify people at risk for osteoporosis

As life expectancy increases worldwide, age-associated diseases such as osteoporosis are having an increasing impact.

19 Jul 2023

Study reveals potential target for repairing beta-cell dysfunction in Type 2 diabetes

Researchers used a murine model to demonstrate that functional excision of murine PITPNA eventually led to hyperglycemia in mice.

19 Jul 2023

Study identifies potential immune biomarker for pulmonary tuberculosis: a step towards early detection

Researchers have identified a potential immune biomarker associated with pulmonary TB in active patients compared to controls.

19 Jul 2023

The immunogenicity and safety of poxvirus-based Nipah vaccines that can be used in humans and species

Researchers characterized the immunogenicity and safety of poxvirus-based Nipah vaccines that can be used in humans and species.

19 Jul 2023

The potential prognostic role of AhRR and PPP1R3C expression in serous ovarian cancer

Study evaluated genes with copy number alterations to identify biomarkers for ovarian cancer prognosis.

18 Jul 2023

Study reports the first local case of mpox caused by imported case in the Chinese mainland

Monkeypox (mpox) is a zoonotic disease caused by the mpox virus (MPXV) that has been primarily limited to Central and West African nations since its discovery.

18 Jul 2023

Breast cancer and MEN1: exploring the connection

Researchers evaluated the role of Multiple Endocrine Neoplasia 1 (MEN1) messenger ribonucleic acid (mRNA) in breast cancer

17 Jul 2023

Researchers demonstrate targeted epigenome editing in the promoter region of several genes using sgRNA/dCas9 complexes

Researchers develop and characterize a highly specific EpiEditing system using catalytically inactivated catalytically inactivated Cas9.

17 Jul 2023

Polymerase News and Research

Study provides valuable insights into the UV susceptibility of SARS-CoV-2 omicron variants

Core promoter variation may drive development of triple-negative breast cancer

Can epigenetic changes explain the strong link between age and cancer?

Cervical fibroblasts in cervical insufficiency patients show impaired responses to progesterone

Tumor-derived GDF-15 suppresses immunotherapy response

Targeting chronic endometritis: study reveals potential diagnostic markers

Unlocking the secrets of asymptomatic COVID-19 infections: HLA-B*15:01 connection revealed

Comparing COVID-19 symptom burden and quality of life in positive and negative PCR test results

Community COVID-19 disease is associated with increased risks of post-viral-illness, fatigue, embolism, and respiratory conditions

Trypsin and anaerobic bacteria boost SARS-CoV-2 Delta variant infectivity: oral hygiene key to prevention

Understanding persistent COVID-19 symptoms: study explores early indicators of long COVID

New brain-penetrant agonist shows promise in protecting dopamine neurons for Parkinson's disease treatment

New biosensor could quickly and inexpensively identify people at risk for osteoporosis

Study reveals potential target for repairing beta-cell dysfunction in Type 2 diabetes

Study identifies potential immune biomarker for pulmonary tuberculosis: a step towards early detection

The immunogenicity and safety of poxvirus-based Nipah vaccines that can be used in humans and species

The potential prognostic role of AhRR and PPP1R3C expression in serous ovarian cancer

Study reports the first local case of mpox caused by imported case in the Chinese mainland

Breast cancer and MEN1: exploring the connection

Researchers demonstrate targeted epigenome editing in the promoter region of several genes using sgRNA/dCas9 complexes

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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