Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Loss of smell following COVID-19 recovery: How long could it last?

In a recent study posted to the Preprints with The Lancet* server, researchers in China conducted a multi-center, retrospective study to gather data on the prevalence of olfactory dysfunction (OD) after three years of recovering from coronavirus disease 2019 (COVID-19).

21 Mar 2023

Paxlovid is 80% effective when taken within 5 days of severe COVID

In a recent study published in The Lancet’s Infectious Diseases, researchers in the United States evaluated nirmatrelvir–ritonavir treatment effectiveness against hospitalizations and deaths among coronavirus disease 2019 (COVID-19) outpatients in the United States of America (USA).

21 Mar 2023

The effectiveness of mRNA vaccines during Omicron BA.4/5 predominance

Researchers evaluate vaccine effectiveness for two, three, and four doses of COVID-19 mRNA first-generation vaccines.

21 Mar 2023

Discovery of 16th century coronavirus in France

In a recent study published in the International Journal of Infectious Diseases, researchers conducted paleoserological tests on dental pulp samples of skeletons excavated from the Abbey Saint-Pierre in the village of Baume-Les-Messieurs in France.

20 Mar 2023

H5N1 avian influenza found in stranded harbor porpoise

In a recent study published in the United States (U.S.) Centers for Disease Control and Prevention (CDC) journal Emerging Infectious Diseases, researchers from Sweden described the detection of the hemagglutinin type 5 and neuraminidase type 1 (H5N1) avian influenza virus in a stranded harbor porpoise, indicating a potential spillover of this highly pathogenic avian influenza virus into cetacean species.

20 Mar 2023

Does vitamin D play an anti-viral role against SARS-CoV-2?

Researchers screened various compounds for anti-viral properties against SARS-CoV-2.

17 Mar 2023

Venous thromboembolism is rare among non-hospitalized COVID-19 patients

In a recent study published in the journal JAMA Network Open, researchers in the United States assessed the risk and aimed to identify the independent predictors of venous thromboembolism events in outpatients who had less severe manifestations of coronavirus disease 2019 (COVID-19).

16 Mar 2023

Research highlights the potential risk of secondary SARS-CoV-2 transmission from wild rats

In a recent study published in the journal mBio, researchers in the United States evaluated rat exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in New York City (NYC).

16 Mar 2023

Research highlights the importance of ventilation and air filtration to reduce pathogen transmission

Testing of ambient air can be used to monitor the community circulation of respiratory pathogens.

16 Mar 2023

Multiplex PCR panels associated with reduced administration of antibiotics to hospitalized GI patients

Acute gastroenteritis afflicts adults of all ages, causing significant suffering and inflicting significant costs on the American healthcare system.

16 Mar 2023

Study identifies link between oral and gut microbiomes and depression

Researchers investigate the role of the oral-gut-brain axis in anxiety and depression.

14 Mar 2023

Study shows SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response

Researchers assessed the association between SARS-CoV-2 infection and DNA damage and cellular senescence.

14 Mar 2023

Oral host responses to SARS-CoV-2 predict progression of COVID-19

In a recent study posted to the medRxiv* preprint server, researchers at the University of North Carolina and the National Institutes of Health determined the associations between oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), oral antibodies against SARS-CoV-2, and coronavirus disease 2019 (COVID-19) symptoms.

14 Mar 2023

Kinetics of successive SARS-CoV-2 infections

Researchers compare viral kinetics of successive SARS-CoV-2 infections.

13 Mar 2023

Hyperinflammation triggers long COVID headaches

Researchers characterize the immunological and metabolic alterations involved in chronic headache onset during post-acute sequelae of COVID-19.

13 Mar 2023

What are the risk factors associated with post-acute SARS-CoV-2 infection?

In a recent study posted to the Research Square* preprint server, researchers assessed the risk factors and predictive models for post-acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

13 Mar 2023

SARS-CoV-2 replication persists for weeks in lungs after symptom onset in severe COVID-19

Researchers observe persistent SARS-CoV-2 replication in severe COVID-19 patient lungs.

13 Mar 2023

How effective are monovalent mRNA COVID-19 vaccine booster doses against Omicron-associated severe outcomes among adults?

Researchers from Canada investigated the efficacy of booster doses of the monovalent mRNA COVID-19 vaccine in preventing hospitalization and death during the dominance of the SARS-CoV-2 Omicron variant.

10 Mar 2023

Individuals with autosomal and X-linked recessive deficiency of IRAK-4 and MyD88 are more susceptible to developing hypoxemic COVID-19 pneumonia

Researchers identified that individuals with a deficiency of myeloid differentiation primary response 88 (MyD88) and interleukin-1 receptor-associated kinase 4 (IRAK-4) due to an autosomal recessive condition were highly susceptible to developing hypoxemic coronavirus disease 2019 (COVID-19) pneumonia when infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

9 Mar 2023

Exploring the prevalence of COVID-19 symptoms in post-acute COVID-19 phase among children and young people

In a recent study published in PLoS ONE, researchers prospectively followed up with children and young people (CYP) diagnosed with post-coronavirus disease 2019 (COVID-19) condition or long COVID to elucidate long COVID symptom profiles over six months.

8 Mar 2023

Polymerase Chain Reaction News and Research

Further Reading

Loss of smell following COVID-19 recovery: How long could it last?

Paxlovid is 80% effective when taken within 5 days of severe COVID

The effectiveness of mRNA vaccines during Omicron BA.4/5 predominance

Discovery of 16th century coronavirus in France

H5N1 avian influenza found in stranded harbor porpoise

Does vitamin D play an anti-viral role against SARS-CoV-2?

Venous thromboembolism is rare among non-hospitalized COVID-19 patients

Research highlights the potential risk of secondary SARS-CoV-2 transmission from wild rats

Research highlights the importance of ventilation and air filtration to reduce pathogen transmission

Multiplex PCR panels associated with reduced administration of antibiotics to hospitalized GI patients

Study identifies link between oral and gut microbiomes and depression

Study shows SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response

Oral host responses to SARS-CoV-2 predict progression of COVID-19

Kinetics of successive SARS-CoV-2 infections

Hyperinflammation triggers long COVID headaches

What are the risk factors associated with post-acute SARS-CoV-2 infection?

SARS-CoV-2 replication persists for weeks in lungs after symptom onset in severe COVID-19

How effective are monovalent mRNA COVID-19 vaccine booster doses against Omicron-associated severe outcomes among adults?

Individuals with autosomal and X-linked recessive deficiency of IRAK-4 and MyD88 are more susceptible to developing hypoxemic COVID-19 pneumonia

Exploring the prevalence of COVID-19 symptoms in post-acute COVID-19 phase among children and young people

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