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Routine eye exams may help detect Alzheimer’s years before symptoms appear

Within the next few years, doctors may be able to spot signs of Alzheimer's disease and other dementias using routine eye exams well before symptoms appear, a new study suggests.

27 Aug 2025

Unlocking neuroglia’s potential to halt neurodegeneration and restore brain homeostasis

In a revealing Genomic Press Interview published today in Brain Medicine, Professor Alexei Verkhratsky dismantles decades of neuroscience orthodoxy with discoveries that position neuroglia as active architects of brain function rather than passive cellular bystanders.

26 Aug 2025

Fat location, not BMI, drives heart ageing risk in men and women

Researchers using UK Biobank imaging data found that where fat is stored in the body, not just how much, determines cardiovascular ageing. Visceral, liver, and muscle fat accelerate ageing, while gynoid fat protects women before menopause.

25 Aug 2025

New insights into bone remodeling process in orthodontic tooth movement under hypoxia

Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report researchers from Institute of Science Tokyo, Japan.

25 Aug 2025

One-stage hybrid operation improves safety in treating hypervascular brain and spinal tumors

Hypervascular tumors of the brain and spinal cord pose serious challenges for neurosurgeons due to their dense blood vessel networks, which can lead to heavy bleeding and increased surgical risk.

21 Aug 2025

How dietary formaldehyde links to worsening diabetes and memory loss

A new review reveals how everyday foods and hidden exposures to formaldehyde may fuel insulin resistance and chip away at memory, but also points to dietary patterns and emerging therapies that could help reduce the risk.

20 Aug 2025

Mitochondrial dysfunction in the blood-brain barrier may contribute to neuropsychiatric disease in 22qDS

In a new study led by the University of Pennsylvania School of Veterinary Medicine (Penn Vet) and Children's Hospital of Philadelphia (CHOP), researchers found that mitochondrial dysfunction in the blood-brain barrier (BBB) may lead to neuropsychiatric disease in some patients with 22qDS.

20 Aug 2025

Rethinking chronic disease management in older adults

Effectively managing chronic conditions like diabetes and hypertension can greatly improve quality of life, reduce complications and extend longevity for older adults.

20 Aug 2025

Elevated TMAO levels linked to higher risk of abdominal aortic aneurysms

Cleveland Clinic researchers have discovered a connection between elevated blood levels of TMAO (trimethylamine N-oxide) - a byproduct of gut bacteria digestion of nutrients found in red meat and other animal products - and a higher risk of abdominal aortic aneurysms.

20 Aug 2025

COVID-19 accelerates vascular aging in women

Research shows COVID-19 accelerates vascular aging, especially in women, with implications for long-term cardiovascular health and recovery strategies.

20 Aug 2025

Somatic mutations drive vascular aging and muscle weakness over time

Two new studies from Karolinska Institutet in Sweden have investigated how mutations that occur in muscles and blood vessels over time can affect aging.

20 Aug 2025

Omega-3 rich diet linked to lower risk of childhood myopia

A diet rich in omega-3 fatty acids, found predominantly in fish oils, may help ward off the development of short sightedness (myopia) in children, while a high intake of saturated fats, found in foods such as butter, palm oil, and red meat, may boost the risk of the condition, finds research published online in the British Journal of Ophthalmology.

20 Aug 2025

Impaired blood flow alters immunity and fuels tumor progression

Cutting off blood flow can prematurely age the bone marrow, weakening the immune system's ability to fight cancer, according to a new study from NYU Langone Health.

19 Aug 2025

COVID-19 ages arteries prematurely with women most affected

COVID-19 may leave arteries biologically “older,” with women showing more persistent stiffness and symptom links than men. Findings from the large CARTESIAN cohort suggest this vascular aging effect is partly reversible over time.

19 Aug 2025

Young adults with bipolar disorder show signs of early heart dysfunction

Cardiovascular disease is the leading cause of premature deaths in patients with bipolar disorder worldwide.

19 Aug 2025

Researchers develop a 3D-bioprinted in vitro model of stenotic brain blood vessels

Cerebrovascular diseases such as atherosclerosis and stroke remain a major cause of morbidity and mortality worldwide.

19 Aug 2025

Improving gene therapy safety with human kidney organoids

Ryuji Morizane, MD, PhD, of the Department of Medicine at Massachusetts General Hospital, is the senior/corresponding author of a new paper published in Signal Transduction and Targeted Therapy, "AAV for gene therapy drives a nephrotoxic response via NFκB in kidney organoids."

19 Aug 2025

Johns Hopkins team develops a more reliable AI for early cancer detection

Two studies led by Johns Hopkins Kimmel Cancer Center, Ludwig Center, and Johns Hopkins Whiting School of Engineering researchers report on a powerful new method that significantly improves the reliability and accuracy of artificial intelligence (AI) for many applications. As an example, they apply the new method to early cancer detection from blood samples, known as liquid biopsy.

19 Aug 2025

Researchers investigate how citrus bioflavonoid naringin could reduce inflammation and heart risk

Researchers reviewed 62 studies on naringin, a citrus flavonoid, and found strong preclinical evidence for its cardioprotective effects, including improved endothelial function, reduced oxidative stress, and protection against myocardial injury.

18 Aug 2025

Exploring the complex origins of endothelial cells in tumor angiogenesis

This newly published review article offers a comprehensive examination of the complexities of tumor angiogenesis and the origins of endothelial cells (ECs) within tumors.

18 Aug 2025