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VRK1 protein may enable cancer cells to colonize new areas of the body during metastasis

Sometimes negative results can point researchers in the right direction. In results published in PLOS ONE on September 4, 2018, scientists at the Medical University of South Carolina examined a protein called vaccinia-related kinase 1 that they hypothesized was important for metastasis. They found that, rather than causing cancer cells to migrate and invade, VRK1 over-expression had the opposite effect.

26 Sep 2018

New born syphilis on the rise sparking concerns

Congenital syphilis or new born syphilis occurs in the new born baby when the mother is affected with the syphilis bacteria during pregnancy or delivery and passes it on to her baby. A new report that was released this Tuesday (25th September 2018) by the US Centres for Disease Control and Prevention (CDC) that showed that in the US, the numbers of these new born syphilis cases have doubled since 2013.

26 Sep 2018

Toxicological evaluation and dosimetry estimation of potential PET radiotracer

The SR101 N-(3-[18F]Fluoropropyl) sulfonamide ([18F]SRF101) is a Sulforhodamine 101 derivative that was previously synthesized by our group.

25 Sep 2018

UC Davis researchers take critical step in developing more effective Salmonella vaccine

UC Davis researchers announce in the Proceedings of the National Academy of Sciences this week a breakthrough in understanding which cells afford optimal protection against Salmonella infection--a critical step in developing a more effective and safe vaccine against a bacterium that annually kills an estimated one million people worldwide.

25 Sep 2018

Vanteres announces new evidence demonstrating role of LPC-DHA in fetal brain development

Vanteres, an innovative biotech company leveraging its biomedical research expertise to develop actively transported lysophospholipids, announces new evidence that demonstrates the critical role of LPC-DHA in normal fetal and infant brain development.

24 Sep 2018

ADCETRIS drug receives approval in Japan as frontline treatment option for Hodgkin lymphoma

Seattle Genetics, Inc. today announced that its collaborator, Takeda Pharmaceutical Company Limited, has received approval from the Japanese Ministry of Health, Labour and Welfare for ADCETRIS (brentuximab vedotin) in combination with doxorubicin, vinblastine and dacarbazine as a frontline treatment option for CD30-positive Hodgkin lymphoma patients in Japan.

24 Sep 2018

China NMPA approves LENVIMA for treatment of unresectable hepatocellular carcinoma

Eisai Co., Ltd. and Merck & Co., Inc., Kenilworth N.J., U.S.A., known as MSD outside of the United States and Canada, announced that the China National Medical Products Administration approved the kinase inhibitor LENVIMA (lenvatinib) as a single agent for the treatment of patients with unresectable hepatocellular carcinoma who have not received prior systemic therapy.

24 Sep 2018

Research shows possibility to postpone cumbersome treatment for low-risk MDS patients

It's possible to postpone the introduction of blood transfusions for an average of 17 months for patients with the low-risk variant of MDS blood cancer, provided they are given erythropoiesis-stimulating agents, which stimulate the body to produce red blood cells, according to a dissertation at Sahlgrenska Academy, Sweden.

24 Sep 2018

CHMP provides positive opinion to Cabometyx for previously-treated patients with hepatocellular carcinoma

Ipsen announced today that the Committee for Medicinal Products for Human Use, the scientific committee of the European Medicines Agency, provided a positive opinion for Cabometyx (cabozantinib) as a monotherapy for the treatment of hepatocellular carcinoma in adults who have been previously treated with sorafenib.

21 Sep 2018

Novel mathematical approach uncovers existence of unsuspected biological cycles

A novel mathematical approach has uncovered that some animal cells have robust 12-hour cycles of genetic activity, in addition to circadian or 24-hour cycles.

20 Sep 2018

Novel method achieves accurate and precise temperature estimation in fat-containing tissues

Magnetic resonance thermometry is the only imaging technique that noninvasively provides temperature distribution in vivo. The water proton resonance frequency shift -based method is the most popular choice for MR temperature monitoring in aqueous tissues.

20 Sep 2018

Progenitor cells for human bone and cartilage have been identified

Research published today describes for the first time the identification of human skeletal stem cells. The discovery may enable the development of novel therapeutic strategies for diseases that cause skeletal degeneration.

20 Sep 2018

UK and European research collaborations receive vote of confidence by three major cancer charities

UK and European research collaborations in cancer research have received a vote of confidence by three major cancer charities, with an announcement today of approximately £30 million into six international projects.

20 Sep 2018

Leading nutritionist explains about different types of iron in oral supplements

Iron is the top nutritional deficiency in the world, as many as 80 percent of people do not have enough iron in their body according to the World Health Organization.

From BetterYou Ltd 19 Sep 2018

Study: Consumption of foods with lower nutritional quality related to increased cancer risk

The consumption of foods with higher scores on the British Food Standards Agency nutrient profiling system (FSAm-NPS), reflecting a lower nutritional quality, is associated with an increased risk of developing cancer, according to a study published this week in PLOS Medicine.

19 Sep 2018

Researchers analyze how exposure to silver nanoparticles affects zebrafish

Silver nanoparticles are increasingly being used in consumer products, such as clothing and personal care products, in the medical and pharmaceutical industry, and in the food industry.

18 Sep 2018

Researchers use CRISPR to identify gene that helps cells resist flavivirus infection

UT Southwestern researchers today report the first use of CRISPR genome-wide screening to identify a gene that helps cells resist flavivirus infection. That nasty class of pathogens includes West Nile virus, dengue fever, Zika virus, and yellow fever.

18 Sep 2018

New studies examine links between fatty liver disease and mitochondrial dysfunction

Researchers at Northeast Ohio Medical University studied the lifespan of mitochondrial proteins in a mouse model of fatty liver disease. Comparing the amount of protein between healthy mice and a mouse model of nonalcoholic fatty liver disease gave them an estimate of each protein's half-life.

17 Sep 2018

Caspase-2 enzyme inhibitor could provide effective way to stop aggressive fatty liver disease

Researchers at University of California San Diego School of Medicine have discovered using mice and human clinical specimens, that caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis, a chronic and aggressive liver condition.

14 Sep 2018

Is ‘precision medicine’ the answer to cancer? Not precisely.

Facing incurable breast cancer at age 55, MaryAnne DiCanto put her faith in "precision medicine" — in which doctors try to match patients with drugs that target the genetic mutations in their tumors. She underwent repeated biopsies to identify therapies that might help.

13 Sep 2018

Liver News and Research

VRK1 protein may enable cancer cells to colonize new areas of the body during metastasis

New born syphilis on the rise sparking concerns

Toxicological evaluation and dosimetry estimation of potential PET radiotracer

UC Davis researchers take critical step in developing more effective Salmonella vaccine

Vanteres announces new evidence demonstrating role of LPC-DHA in fetal brain development

ADCETRIS drug receives approval in Japan as frontline treatment option for Hodgkin lymphoma

China NMPA approves LENVIMA for treatment of unresectable hepatocellular carcinoma

Research shows possibility to postpone cumbersome treatment for low-risk MDS patients

CHMP provides positive opinion to Cabometyx for previously-treated patients with hepatocellular carcinoma

Novel mathematical approach uncovers existence of unsuspected biological cycles

Novel method achieves accurate and precise temperature estimation in fat-containing tissues

Progenitor cells for human bone and cartilage have been identified

UK and European research collaborations receive vote of confidence by three major cancer charities

Leading nutritionist explains about different types of iron in oral supplements

Study: Consumption of foods with lower nutritional quality related to increased cancer risk

Researchers analyze how exposure to silver nanoparticles affects zebrafish

Researchers use CRISPR to identify gene that helps cells resist flavivirus infection

New studies examine links between fatty liver disease and mitochondrial dysfunction

Caspase-2 enzyme inhibitor could provide effective way to stop aggressive fatty liver disease

Is ‘precision medicine’ the answer to cancer? Not precisely.

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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