Therapeutics News and Research

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University of Notre Dame receives funding to help launch diabetic ulcer drug over 'Valley of Death'

Thousands of new chemical structures are tested in hopes of discovering a single drug meant to treat a single disease. Of the 5,000 to 10,000 that are prepared, only about 250 of those make it to the pre-clinical stage, and potentially as few as five make it to clinical trials in humans.

8 Oct 2019

New protein painting technology could transform drug discovery process

George Mason University researchers have discovered the exact location where two proteins responsible for hiding cancer cells from the immune system bind.

8 Oct 2019

Novel drug may be the answer in battling resistance in aggressive breast cancer

Breast cancer is one of the most frequently diagnosed cancers in women across the globe. It represents one in four of all cancers in women. The survival rates for breast cancer vary across the globe, but when it comes to the metastatic or advanced breast cancer type, it is currently incurable, but there are many treatments available.

7 Oct 2019

"Goldilocks" balance holds key to awakening the body's immune response to combat brain cancer

In the story of Goldilocks, a little girl tastes three different bowls of porridge to find which is not too hot, not too cold, but just the right temperature. In a study published in Advanced Therapeutics, University of Minnesota Medical School researchers report on a "Goldilocks" balance which holds the key to awakening the body's immune response to fight off brain cancer.

4 Oct 2019

NUS researcher invents novel transfection technique to deliver DNA into immune cells

Immunotherapy is a promising cancer treatment that uses genetically modified immune cells to fight cancer. It can be used as a primary treatment or in combination with other treatments such as radiation and chemotherapy to slow down or stop the growth of cancer cells and prevent them from spreading to other parts of the body.

4 Oct 2019

Antibody that targets CXCR6 prevents and reverses multiple sclerosis in mouse model

Multiple sclerosis, an autoimmune disorder, is known to be driven by "helper" T cells, white blood cells that mount an inflammatory attack on the brain and spinal cord. A new study from Boston Children's Hospital pinpoints the specific subgroup of helper T cells that cause MS, as well as a protein on their surface, called CXCR6, that marks them.

4 Oct 2019

New study pinpoints emergence and progression of Alzheimer's plaque in the brain

Long before symptoms like memory loss even emerge, the underlying pathology of Alzheimer's disease, such as an accumulation of amyloid protein plaques, is well underway in the brain.

4 Oct 2019

Long-term study data shows DBS is effective for patients with treatment-resistant depression

A study published online on Friday, October 4, in the American Journal of Psychiatry found that deep brain stimulation (DBS) of an area in the brain called the subcallosal cingulate (SCC) provides a robust antidepressant effect that is sustained over a long period of time in patients with treatment-resistant depression--the most severely depressed patients who have not responded to other treatments.

4 Oct 2019

Connected diabetes care can become part of a new diabetes care model

Digital diabetes management systems ("connected diabetes care") have the potential to become part of a new diabetes care model, augmenting the traditional practice of diabetes care by providing continuous and on-demand assistance that aligns with the 24/7 demands of diabetes as a chronic disease.

3 Oct 2019

New project to examine roles of microgravity and cosmic radiation in tumor growth, development

Can weightlessness stop cancer from growing? One of the nine research projects that has been given the go-ahead for the new China Space Station scheduled for 2022 is designed to answer this exact question.

3 Oct 2019

New algorithm can help reduce therapy for some patients with intermediate-risk neuroblastoma

A recent Children's Oncology Group study identified a treatment algorithm that can help reduce therapy for some neuroblastoma patients with intermediate-risk disease, while maintaining good clinical outcomes.

2 Oct 2019

Using AI to transform drug discovery in a big way

According to the National Cancer Institute, approximately 38 percent of men and women will be diagnosed with cancer at some point in their lives.

1 Oct 2019

Researchers to explore if humans can exploit genetics of a mouse that regrows axons after injury

A bit more than a million years ago, a population of Southeastern Asian mice developed the remarkable ability to regrow axons after injury to its brain.

1 Oct 2019

New study helps better understand how type 2 diabetes progresses as a disease

Researchers at Joslin Diabetes Center, an affiliate of Harvard Medical School, have unlocked the key to clearly identifying diseased beta cells in type 2 diabetes.

1 Oct 2019

Detecting neurocognitive change in children with acute lymphoblastic leukemia

Although cure rates for children with cancer are increasing, cancer treatments can cause permanent deterioration of brain functions leading to impairments in attention, concentration, memory and learning. As a result, these changes can lead to challenges with school, obtaining future employment and overall quality of life into adulthood, even though cancer treatment may have been successful.

1 Oct 2019

UC Davis research team receives NIH grant to develop novel drugs for treating pain

A UC Davis research team, led by Vladimir Yarov-Yarovoy and Heike Wulff, will receive a $1.5 million grant from the National Institutes of Health to develop a novel class of peptides that are better at treating pain and don't have the side effects of opioids.

1 Oct 2019

Duke Human Vaccine Institute participates in a large national effort to improve flu shots

As part of a massive national effort to improve and modernize flu shots, the Duke Human Vaccine Institute has received three research contracts from the National Institute of Allergy and Infectious Diseases, with an initial award of approximately $29.6 million in first-year funding.

30 Sep 2019

New imaging technology may help surgeons better detect cancer during surgery

University of Texas at Dallas researchers have demonstrated that imaging technology used to map the universe shows promise for more accurately and quickly identifying cancer cells in the operating room.

30 Sep 2019

High-risk surgical patients with severe aortic stenosis can benefit from new TAVR system

The Portico IDE study found that 30-day safety and one-year effectiveness outcomes of a novel self-expanding transcatheter aortic valve replacement (TAVR) system for patients with severe aortic stenosis (AS) at high or extreme-risk for surgery was noninferior to contemporary FDA-approved TAVR systems available in the United States.

30 Sep 2019

Study: Revascularization with PCI or CABG prolongs survival in patients with left main disease

Patients with left main coronary artery disease (LMCAD) typically have a poor prognosis due to the large amount of myocardium at risk.

30 Sep 2019

Therapeutics News and Research

University of Notre Dame receives funding to help launch diabetic ulcer drug over 'Valley of Death'

New protein painting technology could transform drug discovery process

Novel drug may be the answer in battling resistance in aggressive breast cancer

"Goldilocks" balance holds key to awakening the body's immune response to combat brain cancer

NUS researcher invents novel transfection technique to deliver DNA into immune cells

Antibody that targets CXCR6 prevents and reverses multiple sclerosis in mouse model

New study pinpoints emergence and progression of Alzheimer's plaque in the brain

Long-term study data shows DBS is effective for patients with treatment-resistant depression

Connected diabetes care can become part of a new diabetes care model

New project to examine roles of microgravity and cosmic radiation in tumor growth, development

New algorithm can help reduce therapy for some patients with intermediate-risk neuroblastoma

Using AI to transform drug discovery in a big way

Researchers to explore if humans can exploit genetics of a mouse that regrows axons after injury

New study helps better understand how type 2 diabetes progresses as a disease

Detecting neurocognitive change in children with acute lymphoblastic leukemia

UC Davis research team receives NIH grant to develop novel drugs for treating pain

Duke Human Vaccine Institute participates in a large national effort to improve flu shots

New imaging technology may help surgeons better detect cancer during surgery

High-risk surgical patients with severe aortic stenosis can benefit from new TAVR system

Study: Revascularization with PCI or CABG prolongs survival in patients with left main disease

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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