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Huntington’s disease mutant gene affects brain and body growth in childhood

There is growing evidence to support the hypothesis that there is a neurodevelopmental component to the late-onset neurodegeneration occurring in the brain of huntingtin gene (HTT gene) mutation carriers, and that this increased susceptibility to brain cell death begins during childhood.

6 Jan 2021

Study: Decreased activation of LEF1 gene disrupts ordinary neuronal function

Lithium is considered the gold standard for treating bipolar disorder (BD), but nearly 70 percent of people with BD don't respond to it.

5 Jan 2021

Self-control in childhood may help set people up for healthy midlife aging

Self-control, the ability to contain one's own thoughts, feelings and behaviors, and to work toward goals with a plan, is one of the personality traits that makes a child ready for school. And, it turns out, ready for life as well.

5 Jan 2021

Middle-aged adults with comorbidities high-risk category for COVID-19-related mortality in Mexican study

Researchers from Mexico demonstrate how they calculated age-stratified COVID-19 case fatality rates, years of life lost (YLL), and relative risk for 9 comorbidities and 23 comorbidity combinations in a retrospective study.

5 Jan 2021

Study examines neural mechanisms of specific cognitive tasks of individuals with spinal cord injury

A team of rehabilitation researchers has studied processing speed deficits in individuals with spinal cord injury (SCI), comparing their brain activation patterns with those of healthy age-matched controls, and older healthy individuals.

4 Jan 2021

UOC researchers to study the effects of intermittent fasting on aging in postmenopausal women

Although many treatments are offered for slowing down the impact of aging on health and physical appearance, there are no serious studies that prove their effectiveness on the biological effects of aging.

29 Dec 2020

Study clarifies the effect of aging on hematopoietic stem cells

By transferring mouse aged hematopoietic stem cells (aged HSCs) to the environment of young mice (bone marrow niche), it was demonstrated that the pattern of stem cell gene expression was rejuvenated to that of young hematopoietic stem cells.

24 Dec 2020

Researchers publish study results on challenges of COVID-19 during confinement

The University of Alicante Public Health Research Group has just published the results of a study on the challenges of COVID-19 in Alicante; its effects on health and citizen resistance during confinement.

24 Dec 2020

Researchers discover how shattered chromosomes make cancer cells more aggressive

Cancer is one of the world's greatest health afflictions because, unlike some diseases, it is a moving target, constantly evolving to evade and resist treatment.

23 Dec 2020

COVID-19 severity could be linked to genetic variance

A new study describes some potentially important genetic factors in the host that may shape the clinical symptoms and signs of the disease.

23 Dec 2020

Research shows how colanic acid extends lifespan in C. elegans

Baylor College of Medicine researcher Meng Wang had already shown that bacteria that make a metabolite called colanic acid (CA) could extend the lifespan of worms in her lab by as much as 50%, but her collaboration with Rice University synthetic biologist Jeffrey Tabor is providing tools to answer the bigger question of how the metabolite imparts longer life.

22 Dec 2020

New drug starves cancer cells by attacking mitochondria

A newly developed compound starves cancer cells by attacking their "power plants" - the so-called mitochondria.

22 Dec 2020

Clinical psychologist evaluates the dangers of race-based norms in cognitive testing

A UCSF clinical psychologist has taken aim at the National Football League (NFL) for "race norming" black players diagnosed with dementia, a practice that is depriving them of the monetary awards allocated to former footballers with neurodegenerative disorders.

22 Dec 2020

Study shows how sodium ions drive glutamate transport in the central nervous system

Scientists from the MIPT Research Center for Molecular Mechanisms of Aging and Age-Related Diseases have joined forces with their colleagues from Forschungszentrum Jülich, Germany, and uncovered how sodium ions drive glutamate transport in the central nervous system.

22 Dec 2020

Discovery reveals new type of brain cell sensitive to distance and direction of objects

The existence of GPS-like brain cells, which can store maps of the places we've been, like our kitchen or holiday destination, was already widely known, but this discovery shows there is also a type of brain cell sensitive to the distance and direction of objects that can store their locations on these maps.

21 Dec 2020

Study highlights the far-reaching effects of mutagenic compounds on human health

In order to survive, flourish and successfully reproduce, organisms rely on a high degree of genetic stability. Mutagenic agents, which can threaten the integrity of the genetic code by causing mutations in DNA, pose a serious risk to human health.

21 Dec 2020

Short term “prehabilitation” strength exercises, undertaken pre-surgery, do not prevent muscle loss

Older adults about to undergo elective surgery should undertake a sustained programme of targeted exercise beforehand to counteract the muscle-wasting effects of bedrest, new research suggests.

21 Dec 2020

Anti-hypertension drug may be key to extending lifespan, shows study

A stress response of mitochondria, the part of our cells that produce energy to power bodily functions, is important to a longer life.

18 Dec 2020

Researchers investigate microbiome-mediated therapies for aging and health span

Texas Biomedical Research Institute Associate Professor Corinna Ross, PhD, is a principal investigator on a $3.38 million National Institutes of Health multi-investigator grant to study "microbiome-mediated therapies for aging and healthspan" in marmosets, which are small monkeys native to South America and are becoming increasingly more important in aging and infectious disease research.

18 Dec 2020

Novel device may help restore total eye function

An international consortium of researchers is developing a new method to bring eyes back to life from deceased body donors for clinical research purposes.

18 Dec 2020

Aging News and Research

Huntington’s disease mutant gene affects brain and body growth in childhood

Study: Decreased activation of LEF1 gene disrupts ordinary neuronal function

Self-control in childhood may help set people up for healthy midlife aging

Middle-aged adults with comorbidities high-risk category for COVID-19-related mortality in Mexican study

Study examines neural mechanisms of specific cognitive tasks of individuals with spinal cord injury

UOC researchers to study the effects of intermittent fasting on aging in postmenopausal women

Study clarifies the effect of aging on hematopoietic stem cells

Researchers publish study results on challenges of COVID-19 during confinement

Researchers discover how shattered chromosomes make cancer cells more aggressive

COVID-19 severity could be linked to genetic variance

Research shows how colanic acid extends lifespan in C. elegans

New drug starves cancer cells by attacking mitochondria

Clinical psychologist evaluates the dangers of race-based norms in cognitive testing

Study shows how sodium ions drive glutamate transport in the central nervous system

Discovery reveals new type of brain cell sensitive to distance and direction of objects

Study highlights the far-reaching effects of mutagenic compounds on human health

Short term “prehabilitation” strength exercises, undertaken pre-surgery, do not prevent muscle loss

Anti-hypertension drug may be key to extending lifespan, shows study

Researchers investigate microbiome-mediated therapies for aging and health span

Novel device may help restore total eye function

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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