Infectious Diseases News and Research

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St. Jude gene therapy offers hope for infants with 'bubble boy' disease

Early evidence suggests that gene therapy developed at St. Jude Children's Research Hospital will lead to broad protection for infants with the devastating immune disorder X-linked severe combined immunodeficiency disorder.

11 Dec 2017

SLU scientists provide promising approach in designing new drugs for DMD

In a paper published in the Nature journal Scientific Reports, Saint Louis University researchers report that a new drug reduces fibrosis (scarring) and prevents loss of muscle function in an animal model of Duchenne muscular dystrophy (DMD), providing a promising approach in designing new medications for those suffering from DMD.

8 Dec 2017

University of Adelaide receives $23.2 million for preterm birth research

The University of Adelaide has been awarded $23.2 million for new research tackling some of the world's most significant health problems, including one of the biggest killers of children: preterm birth.

8 Dec 2017

New tests offer better chance for more accurate detection of Lyme disease

New tests to detect early Lyme disease - which is increasing beyond the summer months -could replace existing tests that often do not clearly identify the infection before health problems occur.

7 Dec 2017

BU researchers receive $2.7 million grant to find better ways of delivering anti-retrovirals

Rahm Gummuluru, PhD, associate professor of microbiology at Boston University School of Medicine, and Bjoern Reinhard, PhD, professor of chemistry at Boston University, have been awarded a Research Project Grant from the National Institutes of Allergy and Infectious Diseases/National Institute of Health.

5 Dec 2017

Investigational ZPIV vaccine found to be safe and immunogenic in trial participants

The investigational Zika purified inactivated virus (ZPIV) vaccine was well-tolerated and induced an immune response in participants, according to initial results from three Phase 1 clinical trials.

5 Dec 2017

New approaches show promise to fight against drug-resistant superbugs in hospitals

If you visit a doctor's surgery or hospital you may be asked to apply a hand sanitizer upon entry. Strict hand hygiene practices have become one of the most essential activities in the battle against reducing multi-drug resistant infections in hospitals, nursing homes, and other healthcare settings.

4 Dec 2017

Research could contribute to development of therapeutic drug and vaccine against malaria

Malaria is one of three major infectious diseases affecting approximately 300 million people every year, accounting for about 500,000 deaths, but effective vaccine development has not been successful.

4 Dec 2017

Computer simulations provide insights into plasmonic nanovesicles for drug delivery

Imagine a microscopic gold pill that could travel to a specific location in your body and deliver a drug just where it is needed. This is the promise of plasmonic nanovesicles.

1 Dec 2017

Experts offer research strategies to yield more protective flu vaccine candidates

In a New England Journal of Medicine perspective, experts from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, and the World Health Organization Collaborating Centre for Reference and Research on Influenza in Melbourne discuss how the process of preparing seasonal influenza vaccines in eggs may contribute to their limited effectiveness.

30 Nov 2017

U.S.-funded global effort appears to reduce incidence of new HIV infections

A steep drop in the local incidence of new HIV infections accompanied the rollout of a U.S.-funded anti-HIV program in a large East-African population, according to a study led by researchers at Johns Hopkins Bloomberg School of Public Health and Johns Hopkins School of Medicine.

30 Nov 2017

New genetic study of mosquitoes demonstrates movement of insecticide resistance across Africa

The largest ever genetic study of mosquitoes reveals the movement of insecticide resistance between different regions of Africa and finds several rapidly evolving insecticide resistance genes. Reported today) in Nature, this genetic resource will be used to develop new tools for monitoring resistance and managing insecticide use, and for designing novel control methods.

29 Nov 2017

AIDA project optimizes use of old antibiotics for better patient care

A European consortium of researchers studied five off-patent community and hospital antibiotics with modern methods. They integrated the results of three randomised controlled clinical trials with extensive non-clinical studies.

29 Nov 2017

Inexplicable cases of anaphylaxis caused by uncommon red meat allergy, study finds

While rare, some people experience recurrent episodes of anaphylaxis--a life-threatening allergic reaction that causes symptoms such as the constriction of airways and a dangerous drop in blood pressure--for which the triggers are never identified.

28 Nov 2017

New Canadian guideline outlines cost-effective strategies to prevent HIV in high-risk population

A new Canadian guideline outlines how new biomedical strategies to prevent HIV infection can best be used in high-risk populations both before and after exposure to the virus.

27 Nov 2017

New approach can track how superbugs travel among and within health care facilities

Killer bacteria – ones that have out-evolved our best antibiotics -- may not go away anytime soon. But a new approach to tracking their spread could eventually give us a fighting chance to keep their death toll down.

23 Nov 2017

Emerging technologies, automated systems provide promising solutions for rapid bacterial ID and AST profiling

An SLAS Technology review article by Yiyan Li, Xing Yang and Weian Zhao of University of California, Irvine highlights and synthesizes representative emerging micro- and nanotechnologies, as well as automated systems for bacterial identification (ID) and antibiotic susceptibility testing (AST), including both phenotypic and molecular methods and those at the point-of-care setting.

23 Nov 2017

Scientists detect pathological prion protein in skin of CJD patients

Researchers have found that it was possible to detect abnormal prion protein in the skin of 23 people who died from Creutzfeldt-Jakob Disease (CJD). They also found that exposing mice to skin tissue taken from the CJD patients caused them to develop prion disease.

23 Nov 2017

New technique holds promise to screen cancer cells for drug susceptibility

Doctors have many drugs available to treat multiple myeloma, a type of blood cancer. However, there is no way to predict, by genetic markers or other means, how a patient will respond to a particular drug. This can lead to months of treatment with a drug that isn't working.

20 Nov 2017

Scientists identify biomarkers that predict risk of death in Ebola patients

Scientists have identified a set of biomarkers that indicate which patients infected with the Ebola virus are most at risk of dying from the disease.

17 Nov 2017

Infectious Diseases News and Research

St. Jude gene therapy offers hope for infants with 'bubble boy' disease

SLU scientists provide promising approach in designing new drugs for DMD

University of Adelaide receives $23.2 million for preterm birth research

New tests offer better chance for more accurate detection of Lyme disease

BU researchers receive $2.7 million grant to find better ways of delivering anti-retrovirals

Investigational ZPIV vaccine found to be safe and immunogenic in trial participants

New approaches show promise to fight against drug-resistant superbugs in hospitals

Research could contribute to development of therapeutic drug and vaccine against malaria

Computer simulations provide insights into plasmonic nanovesicles for drug delivery

Experts offer research strategies to yield more protective flu vaccine candidates

U.S.-funded global effort appears to reduce incidence of new HIV infections

New genetic study of mosquitoes demonstrates movement of insecticide resistance across Africa

AIDA project optimizes use of old antibiotics for better patient care

Inexplicable cases of anaphylaxis caused by uncommon red meat allergy, study finds

New Canadian guideline outlines cost-effective strategies to prevent HIV in high-risk population

New approach can track how superbugs travel among and within health care facilities

Emerging technologies, automated systems provide promising solutions for rapid bacterial ID and AST profiling

Scientists detect pathological prion protein in skin of CJD patients

New technique holds promise to screen cancer cells for drug susceptibility

Scientists identify biomarkers that predict risk of death in Ebola patients

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