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UCLA researchers identify new drug delivery pathway to stop tumor growth

Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new drug delivery pathway that may help stop tumor growth and keep cancer from coming back in mice.

25 Sep 2019

Robust replication model of human noroviruses may pave way for effective therapeutics

Zebrafish larvae can serve as a robust replication model of human noroviruses, according to a study published September 19 in the open-access journal PLOS Pathogens by Joana Rocha-Pereira, Peter de Witte and Johan Neyts, of KU Leuven in Belgium, and colleagues.

From PLOS ONE 25 Sep 2019

Inflammasome, Boehringer Ingelheim team up to develop new therapies for retinal diseases

Boehringer Ingelheim and Inflammasome Therapeutics Inc. (Inflammasome) today announced they have entered into a co-development and license agreement to develop up to three therapies for patients with retinal diseases.

From Boehringer Ingelheim International GmbH 25 Sep 2019

Second round of Ebola vaccination trials on the way to DRC

A second experimental Ebola vaccine made by Johnson & Johnson will soon undergo clinical trials in the Ebola affected Democratic Republic of the Congo (DRC) announced health officials. The second round of vaccinations is to begin middle of October this year.

24 Sep 2019

Study identifies factor essential for tendon growth

Insulin-like growth factor 1 (IGF1) is essential for allowing tendons to adapt to physical activity and grow properly, according to basic science research by investigators at Hospital for Special Surgery.

24 Sep 2019

New study shows how fungal biofilm morphology impacts lung disease

Findings from an innovative new study led by researchers at Dartmouth's Geisel School of Medicine and published this week in Nature Microbiology reveal that the way in which human fungal pathogens form colonies can significantly impact their ability to cause disease.

23 Sep 2019

UTHealth's innovative cancer-fighting projects receive $11 million CPRIT funding

Five innovative cancer-fighting projects at The University of Texas Health Science Center at Houston received just over $11 million during the latest round of grants awarded by the Cancer Prevention and Research Institute of Texas

21 Sep 2019

Mutations in specific protein make dengue virus resistant to vaccines and therapeutics

Dengue virus infects about 400 million people annually around the world, with a high prevalence in tropical and sub-tropical regions.

20 Sep 2019

UK receives $8.8 million to support addiction treatment for women in criminal justice settings

The University of Kentucky recently received an $8.8 million grant from the National Institute on Drug Abuse, part of the National Institutes of Health, to establish a Clinical Research Center as part of the Justice Community Opioid Innovation Network to support research on quality addiction treatment for opioid use disorder in criminal justice settings nationwide.

20 Sep 2019

Discovery of combination protein leads to first-in-human clinical trial for leukemia

The discovery of tri-specific natural killer engagers (TriKE™), a combination protein that bridges an immune cell and a tumor cell to drive tumor cell killing power exponentially, has led to a new Phase I, first-in-human study to treat leukemia.

20 Sep 2019

Diarrhea linked significantly to weight gain

A study has shown that obesity is linked to chronic diarrhea, independent of other lifestyle or eating habits.

19 Sep 2019

Study uncovers new factor in the development of childhood lymphoma

A study recently published in the renowned journal Blood, led by Kaan Boztug, Scientific Director of the St. Anna Children's Cancer Research Institute, the Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Adjunct Principal Investigator at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and Associate Professor at the Medical University of Vienna, together with scientists from Israel, Germany, Turkey, Colombia, Argentina and the USA, investigated four patients from independent families with malignancy, autoimmunity and immunodeficiency.

19 Sep 2019

Microrna-based therapy may prove to be effective against chemotherapy-resistant cancers

A technology that manipulates microRNAs developed by Jingfang Ju, PhD, a biochemist and Professor in the Department of Pathology at the Renaissance School of Medicine at Stony Brook University, and colleagues has shown promise when used as anti-cancer therapeutic.

19 Sep 2019

Study opens a promising new front in the fight against pancreatic cancer

Pancreatic adenocarcinoma (PDAC) is a lethal malignancy that most often is resistant to chemotherapy. Researchers have been searching for ways to increase the sensitivity of the tumors to cancer-fighting drugs.

19 Sep 2019

New device uses electromagnetic waves to reverse Alzheimer’s

A new study, to be published in the September 3, 2019, issue of the Journal of Alzheimer's Disease, provides something to cheer about for the estimated 44 million patients who have Alzheimer’s disease (AD) in the US, and their hard-pressed caregivers.

18 Sep 2019

Roswell Park moving three-pronged immunotherapy strategy forward with support from DoD grant

A team from Roswell Park Comprehensive Cancer Center is moving a new three-part strategy for treating advanced cancers forward with support from a U.S. Department of Defense grant to Pawel Kalinski, MD, PhD, Vice Chair for Translational Research and Rustum Family Professor for Molecular Therapeutics and Translational Research at the Buffalo, N.Y.-based cancer center.

18 Sep 2019

Study examines racial disparities in survival outcomes of pediatric patients with Hodgkin lymphoma

In what is believed to be the largest dataset study to date examining the role of race on survival outcome for pediatric patients with Hodgkin lymphoma, investigators at Rutgers Cancer Institute of New Jersey have found that black patients have significantly worse overall survival at five years than white patients when accounting for all available clinical variables.

18 Sep 2019

Therapeutics News and Research

UCLA researchers identify new drug delivery pathway to stop tumor growth

Robust replication model of human noroviruses may pave way for effective therapeutics

Inflammasome, Boehringer Ingelheim team up to develop new therapies for retinal diseases

Second round of Ebola vaccination trials on the way to DRC

Study identifies factor essential for tendon growth

New study shows how fungal biofilm morphology impacts lung disease

UTHealth's innovative cancer-fighting projects receive $11 million CPRIT funding

Mutations in specific protein make dengue virus resistant to vaccines and therapeutics

UK receives $8.8 million to support addiction treatment for women in criminal justice settings

Discovery of combination protein leads to first-in-human clinical trial for leukemia

Diarrhea linked significantly to weight gain

Study uncovers new factor in the development of childhood lymphoma

Microrna-based therapy may prove to be effective against chemotherapy-resistant cancers

Study opens a promising new front in the fight against pancreatic cancer

New device uses electromagnetic waves to reverse Alzheimer’s

Roswell Park moving three-pronged immunotherapy strategy forward with support from DoD grant

Study examines racial disparities in survival outcomes of pediatric patients with Hodgkin lymphoma

Study finds differences in gut bacteria between vaginally born and cesarean-delivered babies

Study: Gene editing may correct genetic mutation responsible for Duchenne muscular dystrophy

New AI-guided robotic platform for automation of synthetic biological molecules

Next-generation therapeutics eBook eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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