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Genome analysis helps detect 568 genes that drive cancer

Analysis of the genomes of 28,000 tumors from 66 types of cancer has led to the identification of 568 cancer driver genes

17 Aug 2020

Women investigators can attract more women patients in heart failure clinical trials

While about a quarter of physicians and researchers working in advanced heart failure (HF) and transplant cardiology are women, representation of women leading HF research remains limited, according to new research led by Penn Medicine.

17 Aug 2020

SARS-CoV-2 spike pocket is a putative target for antiviral design

In a methodologically rigorous study, researchers from the University of Oxford have recently shown how the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein harbors a lipid-binding pocket which modulates the stability of the prefusion trimer and provides conformational shielding from antibodies. Their findings are currently freely available on the bioRxiv* preprint server.

16 Aug 2020

Remains of 17th century Bishop provide insights into the origins of tuberculosis

Bishop Peder Winstrup of Lund, Sweden passed away in the winter of 1679 at the age of 74 and was interred in a crypt at Lund Cathedral.

15 Aug 2020

Influenza-virus-based vaccine platform another viable option against SARS-CoV-2

In a novel proof of concept study, published on the bioRxiv preprint server, U.S. researchers used attenuated influenza viral particles that express severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain to induce neutralizing antibodies in mice – unveiling another viable vaccine candidate for preventing coronavirus disease (COVID-19).

14 Aug 2020

Social connection found to be the strongest protective factor for depression

Researchers from Massachusetts General Hospital (MGH) have identified a set of modifiable factors from a field of over 100 that could represent valuable targets for preventing depression in adults.

14 Aug 2020

Preexisting drug shows promise as a weapon against SARS-CoV-2 virus

First appearing in late 2019 in Wuhan City, China, the SARS-CoV-2 virus continues to cause sickness and death across the globe.

14 Aug 2020

Study identifies new set of multi-tasking taste cells

Our mouths may be home to a newly discovered set of multi-tasking taste cells that - unlike most known taste cells, which detect individual tastes - are capable of detecting sour, sweet, bitter and umami stimuli.

13 Aug 2020

Europeans could have been infected with syphilis before Columbus set sails to America

Columbus brought syphilis to Europe – or did he? A recent study conducted at the University of Zurich now indicates that Europeans could already have been infected with this sexually transmitted disease before the 15th century.

13 Aug 2020

Scientists identify genetic link to predict treatment response in patients with aggressive blood cancer

A Singapore team led by clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) discovered a genetic link to better predict treatment response for relapsed/refractory patients with natural- killer T-cell lymphoma (NKTCL), a highly aggressive form of blood cancer.

13 Aug 2020

Researchers to investigate the role of Connexin 26 protein controlled breathing

The protein Connexin 26 has been previously identified as being directly sensitive to Carbon dioxide and linked to conditions such as KIDS syndrome and deafness.

13 Aug 2020

A triplex SARS-CoV-2 assay based on nanopore sequencing is accurate, rapid and scalable

A novel breakthrough by a research group from Oxford Nanopore Technologies is a rapid way of testing and screening large numbers of samples for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

12 Aug 2020

Researchers develop new strategies to treat osteoporosis

A research team from the National University of Singapore (NUS) has identified a new avenue to maintain bone health while reducing bone resorption.

12 Aug 2020

Study sheds new light on mechanisms of cohesin function involved in cancer and cardiac development

Ana Losada, from the Spanish National Cancer Research Centre (CNIO), is the scientist who identified cohesin in vertebrates, a protein that is essential in cell division.

12 Aug 2020

SARS-CoV-2 a "swarm" of mutant viruses

In this new study, the virus was serially passaged in independent cell types in a controlled environment. The researchers found that the virus rapidly adapts to the changing conditions in culture by selecting for pre-existing species.

12 Aug 2020

Mouse study shows potential new way to unlock the power of immunotherapy for cancer patients

Immunotherapy has revolutionized cancer treatment by stimulating the patient's own immune system to attack cancer cells, yielding remarkably quick and complete remission in some cases. But such drugs work for less than a quarter of patients because tumors are notoriously adept at evading immune assault.

11 Aug 2020

Genome News and Research

Genome analysis helps detect 568 genes that drive cancer

Women investigators can attract more women patients in heart failure clinical trials

SARS-CoV-2 spike pocket is a putative target for antiviral design

Remains of 17th century Bishop provide insights into the origins of tuberculosis

Influenza-virus-based vaccine platform another viable option against SARS-CoV-2

Social connection found to be the strongest protective factor for depression

Preexisting drug shows promise as a weapon against SARS-CoV-2 virus

Study identifies new set of multi-tasking taste cells

Europeans could have been infected with syphilis before Columbus set sails to America

Scientists identify genetic link to predict treatment response in patients with aggressive blood cancer

Researchers to investigate the role of Connexin 26 protein controlled breathing

A triplex SARS-CoV-2 assay based on nanopore sequencing is accurate, rapid and scalable

Researchers develop new strategies to treat osteoporosis

Study sheds new light on mechanisms of cohesin function involved in cancer and cardiac development

SARS-CoV-2 a "swarm" of mutant viruses

Mouse study shows potential new way to unlock the power of immunotherapy for cancer patients

New research on COVID-19 and aging

Researchers discover dose threshold that improves delivery of cancer-fighting drugs into a tumor

Genomic sequencing falls short as a standalone screening tool for newborns

Rice engineers use gene editing to facilitate drug discovery based on natural fungus

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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