Infectious Diseases News and Research

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Investigational ZPIV vaccine found to be safe and immunogenic in trial participants

The investigational Zika purified inactivated virus (ZPIV) vaccine was well-tolerated and induced an immune response in participants, according to initial results from three Phase 1 clinical trials.

5 Dec 2017

New approaches show promise to fight against drug-resistant superbugs in hospitals

If you visit a doctor's surgery or hospital you may be asked to apply a hand sanitizer upon entry. Strict hand hygiene practices have become one of the most essential activities in the battle against reducing multi-drug resistant infections in hospitals, nursing homes, and other healthcare settings.

4 Dec 2017

Research could contribute to development of therapeutic drug and vaccine against malaria

Malaria is one of three major infectious diseases affecting approximately 300 million people every year, accounting for about 500,000 deaths, but effective vaccine development has not been successful.

4 Dec 2017

Computer simulations provide insights into plasmonic nanovesicles for drug delivery

Imagine a microscopic gold pill that could travel to a specific location in your body and deliver a drug just where it is needed. This is the promise of plasmonic nanovesicles.

1 Dec 2017

Experts offer research strategies to yield more protective flu vaccine candidates

In a New England Journal of Medicine perspective, experts from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, and the World Health Organization Collaborating Centre for Reference and Research on Influenza in Melbourne discuss how the process of preparing seasonal influenza vaccines in eggs may contribute to their limited effectiveness.

30 Nov 2017

U.S.-funded global effort appears to reduce incidence of new HIV infections

A steep drop in the local incidence of new HIV infections accompanied the rollout of a U.S.-funded anti-HIV program in a large East-African population, according to a study led by researchers at Johns Hopkins Bloomberg School of Public Health and Johns Hopkins School of Medicine.

30 Nov 2017

New genetic study of mosquitoes demonstrates movement of insecticide resistance across Africa

The largest ever genetic study of mosquitoes reveals the movement of insecticide resistance between different regions of Africa and finds several rapidly evolving insecticide resistance genes. Reported today) in Nature, this genetic resource will be used to develop new tools for monitoring resistance and managing insecticide use, and for designing novel control methods.

29 Nov 2017

AIDA project optimizes use of old antibiotics for better patient care

A European consortium of researchers studied five off-patent community and hospital antibiotics with modern methods. They integrated the results of three randomised controlled clinical trials with extensive non-clinical studies.

29 Nov 2017

Inexplicable cases of anaphylaxis caused by uncommon red meat allergy, study finds

While rare, some people experience recurrent episodes of anaphylaxis--a life-threatening allergic reaction that causes symptoms such as the constriction of airways and a dangerous drop in blood pressure--for which the triggers are never identified.

28 Nov 2017

New Canadian guideline outlines cost-effective strategies to prevent HIV in high-risk population

A new Canadian guideline outlines how new biomedical strategies to prevent HIV infection can best be used in high-risk populations both before and after exposure to the virus.

27 Nov 2017

New approach can track how superbugs travel among and within health care facilities

Killer bacteria – ones that have out-evolved our best antibiotics -- may not go away anytime soon. But a new approach to tracking their spread could eventually give us a fighting chance to keep their death toll down.

23 Nov 2017

Emerging technologies, automated systems provide promising solutions for rapid bacterial ID and AST profiling

An SLAS Technology review article by Yiyan Li, Xing Yang and Weian Zhao of University of California, Irvine highlights and synthesizes representative emerging micro- and nanotechnologies, as well as automated systems for bacterial identification (ID) and antibiotic susceptibility testing (AST), including both phenotypic and molecular methods and those at the point-of-care setting.

23 Nov 2017

Scientists detect pathological prion protein in skin of CJD patients

Researchers have found that it was possible to detect abnormal prion protein in the skin of 23 people who died from Creutzfeldt-Jakob Disease (CJD). They also found that exposing mice to skin tissue taken from the CJD patients caused them to develop prion disease.

23 Nov 2017

New technique holds promise to screen cancer cells for drug susceptibility

Doctors have many drugs available to treat multiple myeloma, a type of blood cancer. However, there is no way to predict, by genetic markers or other means, how a patient will respond to a particular drug. This can lead to months of treatment with a drug that isn't working.

20 Nov 2017

Scientists identify biomarkers that predict risk of death in Ebola patients

Scientists have identified a set of biomarkers that indicate which patients infected with the Ebola virus are most at risk of dying from the disease.

17 Nov 2017

Scientists suggest possibility of naturally acquired immunity against Zika infection

Birth defects in babies born infected with Zika virus remain a major health concern. Now, scientists suggest the possibility that some women in high-risk Zika regions may already be protected and not know it.

16 Nov 2017

Brazilian Zika epidemic could soon be over, say scientists

In 2016, news about the Zika virus in Brazil made the headlines in Europe for the first time. With approximately 65 million people affected, it is one of the largest epidemics in the last few years.

16 Nov 2017

New model provides better understanding of epidemic spreading in realistic circumstances

New approaches are needed to control the spread of epidemic diseases, according to the developers of a new model of the way pathogens can 'cooperate'.

16 Nov 2017

UCR researchers develop transgenic mosquitoes to help reduce spread of infectious diseases

Researchers at the University of California, Riverside have developed transgenic mosquitoes that stably express the Cas9 enzyme in their germline. The addition of Cas9 will enable the use of the CRISPR gene editing tool to make efficient, targeted changes to the mosquitoes' DNA.

14 Nov 2017

New health analysis in India finds increase in non-communicable diseases

A new state-by-state health analysis in India finds that over two decades heart- and lung-related conditions, as well as other non-communicable diseases (NCDs), have surpassed infectious diseases, such as diarrhea and tuberculosis, as the nation's leading killers.

14 Nov 2017

Infectious Diseases News and Research

Investigational ZPIV vaccine found to be safe and immunogenic in trial participants

New approaches show promise to fight against drug-resistant superbugs in hospitals

Research could contribute to development of therapeutic drug and vaccine against malaria

Computer simulations provide insights into plasmonic nanovesicles for drug delivery

Experts offer research strategies to yield more protective flu vaccine candidates

U.S.-funded global effort appears to reduce incidence of new HIV infections

New genetic study of mosquitoes demonstrates movement of insecticide resistance across Africa

AIDA project optimizes use of old antibiotics for better patient care

Inexplicable cases of anaphylaxis caused by uncommon red meat allergy, study finds

New Canadian guideline outlines cost-effective strategies to prevent HIV in high-risk population

New approach can track how superbugs travel among and within health care facilities

Emerging technologies, automated systems provide promising solutions for rapid bacterial ID and AST profiling

Scientists detect pathological prion protein in skin of CJD patients

New technique holds promise to screen cancer cells for drug susceptibility

Scientists identify biomarkers that predict risk of death in Ebola patients

Scientists suggest possibility of naturally acquired immunity against Zika infection

Brazilian Zika epidemic could soon be over, say scientists

New model provides better understanding of epidemic spreading in realistic circumstances

UCR researchers develop transgenic mosquitoes to help reduce spread of infectious diseases

New health analysis in India finds increase in non-communicable diseases

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