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Zombie cicadas infected with mind-controlling fungus

Mind-controlling fungus that infects the brains of cicadas can make them kill each other. These mutant critters, dubbed as zombie cicadas, are forced to infect other insects.

5 Aug 2020

Genetic variation influencing chromatin states associated with neuropsychiatric disorders

A new study led by NorthShore University HealthSystem and the University of Chicago took a novel approach to identifying SNPs influencing the risk of neuropsychiatric disorders like schizophrenia, bipolar and major depressive disorder, the institutions announced today.

4 Aug 2020

Study identifies impact of gene mutations on severity of myelodysplastic syndrome

The Myelodysplastic Syndromes Group of Josep Carreras Leukaemia Research Institute, led by Dr. Francesc Solé, has participated in the first international study that confirms that having two mutated copies of the TP53 gene, as opposed to a single mutated copy, is associated with a worse prognosis in patients diagnosed with myelodysplastic syndrome (MDS).

4 Aug 2020

Picomolar inhibitors to SARS-CoV-2 proteins

Now, a new study published on the preprint server bioRxiv in August 2020 reports the development of mini-inhibitors based on computational design, that are suitable for such topical use.

4 Aug 2020

Novel mutation identified in SARS-CoV-2 spike protein from Sweden

Researchers from Sweden and Brazil have identified a novel mutation in a strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) obtained from a patient in Stockholm, Sweden, in late April.

4 Aug 2020

Normal DNA repair process can lead to mutations in cancer

Hypermutation is an unusual occurence that can lead to many nearby mutations at once, severely damaging our genetic material and potentially causing cancer.

4 Aug 2020

Regulatory mechanisms involved in brain development are same for insects and mammals

With these new findings scientists can potentially better understand the subtle changes that can occur in genes and brain circuits that can lead to mental health disorders such as anxiety and autism spectrum disorders.

4 Aug 2020

Researchers develop scalable strategy to find novel molecular glue degraders

Despite enormous efforts to advance traditional pharmacology approaches, more than three quarters of all human proteins remain beyond the reach of therapeutic development.

4 Aug 2020

Study solves long-held controversy over two popular bird species

A half-century of controversy over two popular bird species may have finally come to an end. In one corner: the Bullock's Oriole, found in the western half of North America. In the other corner: the Baltimore Oriole, breeding in the eastern half.

4 Aug 2020

Study reveals impact of TP53 gene mutations on MDS severity

Considered the "guardian of the genome," TP53 is the most commonly mutated gene in cancer. TP53's normal function is to detect DNA damage and prevent cells from passing this damage on to daughter cells.

3 Aug 2020

Extensive study of SARS-CoV-2 sequencing reveals six strains of the virus

The virus causing the COVID-19 pandemic, SARS-CoV-2, presents at least six strains. Despite its mutations, the virus shows little variability, and this is good news for the researchers working on a viable vaccine.

3 Aug 2020

Study investigates genetic determinants of stroke in individuals of African descent

African-Americans have up to three times the risk of dying from strokes as people of European descent, yet there has been little investigation of if and how genetic variants contribute to their elevated stroke risk. Until now.

3 Aug 2020

Long stretches of repeating DNA associated with susceptibility to systemic sclerosis

Researchers from the University of Tsukuba show that long stretches of repeat DNA sequences in the gene FLI1 are associated with susceptibility to systemic sclerosis.

2 Aug 2020

Synthetic riboregulators detect SARS-CoV-2 genome parts in 40 minutes

By exploiting the tools of synthetic biology, the researchers from Turkey have successfully developed a de novo riboregulator system for rapidly detecting the presence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomic material. Their paper is currently available on medRxiv preprint server.

2 Aug 2020

Understanding the causal relationships between diabetes, obesity and NAFLD

Diabetes, obesity and nonalcoholic fatty liver disease (NAFLD) are all common diseases that can lead to serious health implications.

31 Jul 2020

15 young scientists receive Damon Runyon Fellowship Award to pursue cancer research

Grants totaling nearly $3.5 million give early career investigators independence to pursue brave and bold cancer research.

31 Jul 2020

Researchers report a liquid biopsy for COVID-19

A new study published on the preprint server medRxiv in July 2020 reports the potential of cell-free DNA as a marker of the severity of disease in COVID-19. This could help triage patients as well as provide a prognostic marker.

30 Jul 2020

CZI, CZ Biohub, and The State Of California join forces to track COVID-19 transmission

Today, the Chan Zuckerberg Biohub, in partnership with the Chan Zuckerberg Initiative, announced that it will provide free whole genome sequencing and analysis of the SARS-CoV-2 virus to all California Departments of Public Health and California local health jurisdictions through a newly-launched effort called the California COVID Tracker.

30 Jul 2020

Research shows how Zika virus succeeds in protecting key parts of its genome

To fight viruses, cells can deploy defence enzymes that progressively destroy viral genome strands starting from one of the two strand ends. However, this degradation mechanism is not effective against epidemic viruses such as Zika.

30 Jul 2020

Immunosuppressive steroids help tumors to evade the immune system

A new study has revealed that tumors can evade the immune system by telling immune cells to produce immunosuppressive steroids.

30 Jul 2020

Genome News and Research

Zombie cicadas infected with mind-controlling fungus

Genetic variation influencing chromatin states associated with neuropsychiatric disorders

Study identifies impact of gene mutations on severity of myelodysplastic syndrome

Picomolar inhibitors to SARS-CoV-2 proteins

Novel mutation identified in SARS-CoV-2 spike protein from Sweden

Normal DNA repair process can lead to mutations in cancer

Regulatory mechanisms involved in brain development are same for insects and mammals

Researchers develop scalable strategy to find novel molecular glue degraders

Study solves long-held controversy over two popular bird species

Study reveals impact of TP53 gene mutations on MDS severity

Extensive study of SARS-CoV-2 sequencing reveals six strains of the virus

Study investigates genetic determinants of stroke in individuals of African descent

Long stretches of repeating DNA associated with susceptibility to systemic sclerosis

Synthetic riboregulators detect SARS-CoV-2 genome parts in 40 minutes

Understanding the causal relationships between diabetes, obesity and NAFLD

15 young scientists receive Damon Runyon Fellowship Award to pursue cancer research

Researchers report a liquid biopsy for COVID-19

CZI, CZ Biohub, and The State Of California join forces to track COVID-19 transmission

Research shows how Zika virus succeeds in protecting key parts of its genome

Immunosuppressive steroids help tumors to evade the immune system

Genetics & Genomics - Second Edition eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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