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Novel drug combination shows promise for treating advanced skin cancers in kidney transplant recipients

People who have had a kidney transplant are at high risk for developing skin cancers. New research directed by investigators from the Johns Hopkins Kimmel Cancer Center is exploring the best combination of treatments to target skin cancers while preserving the transplanted organs.

28 Feb 2024

Anti-cancer drug shows promise in treating brain injuries after stroke

A study by the Institut de Neurociències of the UAB (INc-UAB) demonstrates in animal models the benefits of vorinostat after having suffered a stroke.

28 Feb 2024

Novel "Tissue-in-a-CUBE" model mimics blood-brain barrier for drug testing

A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has succeeded in establishing a model of the blood-brain barrier using modularized tissue derived from human cells.

28 Feb 2024

Novel brain organoid model unveils link between inflammation and astrocyte dysfunction

The brain is typically depicted as a complex web of neurons sending and receiving messages. But neurons only make up half of the human brain.

28 Feb 2024

Sinusitis tied to elevated rheumatic disease risk

The common inflammatory condition sinusitis is linked to a 40% heightened risk of a subsequent diagnosis of rheumatic disease, particularly in the 5 to 10 years preceding the start of symptoms, finds research published in the open access journal RMD Open.

27 Feb 2024

Universal, essential biomarker identified for childhood neuroblastoma

Researchers have newly identified a universal, essential biomarker for the childhood cancer neuroblastoma – and a potential new target for treatment.

27 Feb 2024

Fenugreek seeds: A superfood for health and wellness, says new review

Research highlights the dietary significance and potential applications of fenugreek seeds, emphasizing their role in disease prevention, chronic condition management, and providing nutritional value, including their ability to reduce blood sugar and cholesterol levels.

27 Feb 2024

Study reveals distinct molecular features of proximal and distal colon cancers

The colon is often thought of as one organ, but the right and left parts of the colon have different molecular features in cancers.

27 Feb 2024

UMass Amherst study targets aplastic anemia with cell retraining approach

Researchers at the University of Massachusetts Amherst recently released a first-of-its-kind study that focuses on the rare autoimmune disorder aplastic anemia to understand how a subset of cells might be trained to correct the overzealous immune response that can lead to fatal autoimmune disorders.

27 Feb 2024

Discovery of bicarbonate-sensing receptor offers therapeutic insights into ischemic stroke treatment

Researchers have identified this receptor in brain mural cells that regulates reperfusion injury.

27 Feb 2024

Secondhand smoke exposure reduces chemotherapy effectiveness in head and neck cancer patients

People who are diagnosed with head and neck cancer often receive a standard type of chemotherapy as part of their treatment.

27 Feb 2024

Study uncovers the anti-aging role of vitamin D and vitamin D receptor in Drosophila midgut model

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 3, entitled, "The anti-aging effect of vitamin D and vitamin D receptor in Drosophila midgut."

27 Feb 2024

Study finds metabolic checkpoint PHGDH as potential target to modulate tumor-associated macrophages

A study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in the top-class journal Cellular & Molecular Immunology, has a promising result from tumor research: The enzyme phosphoglycerate dehydrogenase (PHDGH) acts as a metabolic checkpoint in the function of tumor-associated macrophages (TAMs) and thus on tumor growth.

27 Feb 2024

Ancient Eastern Arabians developed malaria resistance through agriculture, study finds

People living in ancient Eastern Arabia appear to have developed resistance to malaria following the appearance of agriculture in the region around five thousand years ago, a new study reveals.

27 Feb 2024

Bio-Rad launches vericheck ddPCR replication competent lentivirus and replication competent AAV kits for cell and gene therapy production

Rapid, Sensitive, and Validated Detection of Viral Replication Genes Using Droplet Digital™ PCR During Cell and Gene Therapy Production.

From Bio-Rad Laboratories 27 Feb 2024

Mapping the brain: How cell types and location influence Parkinson’s disease

A single-cell spatial transcriptome analysis on murine brain expression in age and disease using a Parkinson's disease.

27 Feb 2024

Research unveils major discovery in gut-brain axis communication

The mechanisms by which antidepressants and other emotion-focused medications work could be reconsidered due to an important new breakthrough in the understanding of how the gut communicates with the brain.

26 Feb 2024

Flavonol-rich diet linked to lower mortality and disease risk, study shows

Study finds that higher dietary intake of flavonol is linked to reduced all-cause mortality and lower risk of Alzheimer's disease, cancer, and cardiovascular disease in US adults.

26 Feb 2024

Vaping increases susceptibility to COVID-19 infection, study finds

Vapers are susceptible to infection by SARS-CoV-2, the virus that spreads COVID-19 and continues to infect people around the world, a University of California, Riverside, study has found.

26 Feb 2024

Boston College biologist wins NIH grant to study viral insulins for cancer treatment

Boston College Assistant Professor of Biology Emrah Altindis has been awarded a five-year, $2.5-million grant from the National Institutes of Health to study viral insulins and mechanisms related to IGF-1 receptor protein inhibition and its potential applications in cancer treatment.

26 Feb 2024

B Cell News and Research

Novel drug combination shows promise for treating advanced skin cancers in kidney transplant recipients

Anti-cancer drug shows promise in treating brain injuries after stroke

Novel "Tissue-in-a-CUBE" model mimics blood-brain barrier for drug testing

Novel brain organoid model unveils link between inflammation and astrocyte dysfunction

Sinusitis tied to elevated rheumatic disease risk

Universal, essential biomarker identified for childhood neuroblastoma

Fenugreek seeds: A superfood for health and wellness, says new review

Study reveals distinct molecular features of proximal and distal colon cancers

UMass Amherst study targets aplastic anemia with cell retraining approach

Discovery of bicarbonate-sensing receptor offers therapeutic insights into ischemic stroke treatment

Secondhand smoke exposure reduces chemotherapy effectiveness in head and neck cancer patients

Study uncovers the anti-aging role of vitamin D and vitamin D receptor in Drosophila midgut model

Study finds metabolic checkpoint PHGDH as potential target to modulate tumor-associated macrophages

Ancient Eastern Arabians developed malaria resistance through agriculture, study finds

Bio-Rad launches vericheck ddPCR replication competent lentivirus and replication competent AAV kits for cell and gene therapy production

Mapping the brain: How cell types and location influence Parkinson’s disease

Research unveils major discovery in gut-brain axis communication

Flavonol-rich diet linked to lower mortality and disease risk, study shows

Vaping increases susceptibility to COVID-19 infection, study finds

Boston College biologist wins NIH grant to study viral insulins for cancer treatment

Using single B cell screening to boost antibody discovery eBook

Expanding access to NMR with the Fourier 80 Duo

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