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What you need to know about the drug price fight in those TV ads

In recent months ominous ads about prescription drugs have flooded the TV airwaves. Perhaps by design, it's not always clear who's sponsoring the ads or why.

10 Jul 2023

Proposed PFAS rule would cost companies estimated $1B; lacks limits and cleanup requirement

A proposed federal rule calls for forcing companies to disclose whether their products contain toxic "forever" chemicals, the government's first attempt at cataloging the pervasiveness of PFAS across the United States.

10 Jul 2023

Meet the people deciding how to spend $50 billion in opioid settlement cash

As more than $50 billion makes its way to state and local governments to compensate for the opioid epidemic, people with high hopes for the money are already fighting over a little-known bureaucratic arm of the process: state councils that wield immense power over how the cash is spent.

10 Jul 2023

Australian rainforest remedies: Scientists explore bioactive plant compounds as potential anti-neuroinflammatory agents

Research discusses the process of discovering anti-inflammatory and neuroprotective drugs from medicinal plants found in the Australian rainforest. It focuses on the pathways from the discovery of bioactive plants to the validation in an appropriate neuro-inflammatory mouse model, using some examples from their current research.

9 Jul 2023

Unique blood protein patterns in long COVID patients could reveal potential drug targets

Recently published in The Journal of Translational Medicine, a team at Lawson Health Research Institute has discovered unique patterns of blood plasma proteins in patients with long COVID that could reveal potential drug targets to improve patient outcomes.

7 Jul 2023

AI tool can rapidly decode brain tumor DNA during surgery

Scientists have designed an AI tool that can rapidly decode a brain tumor's DNA to determine its molecular identity during surgery - critical information that under the current approach can take a few days and up to a few weeks.

7 Jul 2023

Triple combination therapy shows promise in long-term treatment of cystic fibrosis

The mucus in the airways is not as sticky, inflammation in the lungs significantly reduced: Triple combination therapy can achieve these positive, lasting effects in patients with cystic fibrosis (CF).

7 Jul 2023

Fecal transplants safe and effective in treating advanced melanoma, clinical trial shows

In a world-first clinical trial published in the journal Nature Medicine, a multi-center study from Lawson Health Research Institute, the Centre hospitalier de l'Université de Montréal and the Jewish General Hospital (JGH) has found fecal microbiota transplants (FMT) from healthy donors are safe and show promise in improving response to immunotherapy in patients with advanced melanoma.

7 Jul 2023

New molecular pathway identified for early onset coronary artery disease

A novel molecular pathway to explain how a mutation in the gene ACTA2 can cause individuals in their 30s – with normal cholesterol levels and no other risk factors - to develop coronary artery disease has been identified, according to researchers with UTHealth Houston.

7 Jul 2023

Cryo-EM helps decode the molecular architecture of a neural transport protein

Using Cryo-EM, a powerful microscopy technique, researchers at IISc and collaborators have decoded the molecular architecture of a transporter protein controlling the movement of a key neurotransmitter.

6 Jul 2023

THC use during pregnancy could lead to life-long health impacts for offspring

Oregon Health & Science University researchers showed that consuming THC while pregnant could potentially affect development of the fetus and lead to life-long health impacts for offspring.

6 Jul 2023

Multiple discoveries open new paths for early prediction of Parkinson's disease trajectories

Hand tremors and slowed movements are two of the most widely recognized hallmarks of Parkinson's disease, and for many sufferers the first indication that something is amiss.

6 Jul 2023

Aneuploidy could function as a therapeutic target for cancer

Cancer cells with extra chromosomes depend on those chromosomes for tumor growth, a new Yale study reveals, and eliminating them prevents the cells from forming tumors.

6 Jul 2023

Why the next big hope for Alzheimer’s might not help most Black patients

This week the FDA is expected to approve what many scientists and doctors believe is the first drug to show promise of slowing the progression of Alzheimer's disease.

6 Jul 2023

New therapy to mitigate fragile X syndrome may be on the horizon

An antisense therapy developed by Joel D. Richter, PhD, Sneha Shah, PhD, and Jonathan K. Watts, PhD, at UMass Chan Medical School and Elizabeth Berry-Kravis, MD, PhD, at RUSH University Medical Center, restores production of the protein FMRP in cell samples taken from patients with fragile X syndrome.

5 Jul 2023

New protein found to help melanoma evade the immune system

New research from Sanford Burnham Prebys has helped explain how melanoma evades the immune system and may guide the discovery of future therapies for the disease.

5 Jul 2023

Less than half of approved new drugs add substantial therapeutic value over existing treatments

New drugs are often used not only for one disease (first approved indication) but also for other diseases (supplemental indications).

5 Jul 2023

Biomarker found in urine could help diagnose acute tubulointerstitial nephritis

In a study led by Johns Hopkins Medicine, in collaboration with Yale School of Medicine, researchers have identified a biomarker found via a simple urine test that can be used to diagnose acute tubulointerstitial nephritis (AIN), a medical condition that causes inflammation of the kidneys and can lead to acute kidney injury (AKI) — a sudden loss of kidney function.

5 Jul 2023

Clinical trial of three-month TB treatment regimen closed due to high rate of unfavorable outcomes

The first clinical trial of a three-month tuberculosis (TB) treatment regimen is closing enrollment because of a high rate of unfavorable outcomes with the investigational course of treatment.

5 Jul 2023

Study identifies role of ROR1 in pancreatic cancer metastasis

Tumor-initiating cells, or cancer stem cells, are gaining attention in cancer therapy, as they can travel through the body and cause cancerous tumors at other sites through metastasis.

5 Jul 2023

Drugs News and Research

What you need to know about the drug price fight in those TV ads

Proposed PFAS rule would cost companies estimated $1B; lacks limits and cleanup requirement

Meet the people deciding how to spend $50 billion in opioid settlement cash

Australian rainforest remedies: Scientists explore bioactive plant compounds as potential anti-neuroinflammatory agents

Unique blood protein patterns in long COVID patients could reveal potential drug targets

AI tool can rapidly decode brain tumor DNA during surgery

Triple combination therapy shows promise in long-term treatment of cystic fibrosis

Fecal transplants safe and effective in treating advanced melanoma, clinical trial shows

New molecular pathway identified for early onset coronary artery disease

Cryo-EM helps decode the molecular architecture of a neural transport protein

THC use during pregnancy could lead to life-long health impacts for offspring

Multiple discoveries open new paths for early prediction of Parkinson's disease trajectories

Aneuploidy could function as a therapeutic target for cancer

Why the next big hope for Alzheimer’s might not help most Black patients

New therapy to mitigate fragile X syndrome may be on the horizon

New protein found to help melanoma evade the immune system

Less than half of approved new drugs add substantial therapeutic value over existing treatments

Biomarker found in urine could help diagnose acute tubulointerstitial nephritis

Clinical trial of three-month TB treatment regimen closed due to high rate of unfavorable outcomes

Study identifies role of ROR1 in pancreatic cancer metastasis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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