Efficacy News and Research

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MAPK4 may play a key role in triple-negative breast cancer

Scientific evidence supporting the involvement of the enzyme MAPK4 in cancer growth and resistance to certain therapies has been growing quickly.

12 Jan 2022

An egg-derived SARS-CoV-2 vaccine and treatment for COVID-19 disease

A new study, posted to the medRxiv* preprint server, has focussed on the development of intranasal prophylaxis against SARS-CoV-2 infection.

11 Jan 2022

Engineering higher affinity SARS-CoV-2 antibodies

A new study describes the potential of engineered neutralizing antibodies that have a high affinity for the binding epitopes.

11 Jan 2022

Study opens up prospects for using virotherapy to treat central nervous system tumors

In a study conducted at the University of São Paulo's Human Genome and Stem Cell Research Center (HUG-CELL) in Brazil, serial systemic injections of zika virus into mice with brain tumors destroyed the cancer without causing neurological damage or injuring other organs, and increased the animals' survival rate.

11 Jan 2022

Third dose of mRNA COVID vaccine induces strong immunity in older adults

A new study describes the beneficial effects of a third dose of the COVID-19 mRNA vaccine in strengthening immunity among older adults.

11 Jan 2022

Phase 1 clinical trial shows the safety, feasibility of CAR-M cell therapy for solid tumors

Preliminary findings from Penn Medicine in an ongoing first-in-human clinical trial examining the safety, tolerability and feasibility of chimeric antigen receptor macrophage (CAR-M) has helped to establish the viability of this innovative immunotherapy, which advances the trailblazing scientific discovery of CAR T cell therapy- also pioneered at Penn- for solid cancer tumors and offers a promising new strategy in the fight against cancer.

11 Jan 2022

Withdrawing steroid treatment found to boost SARS-CoV-2 vaccine-induced immunity in kidney transplant recipients

In a new study, a team of researchers investigated the impact of the fourth dose of a vaccine against COVID-19 in kidney transplant recipients, who had not mounted a humoral immune response to three doses of vaccine.

11 Jan 2022

Study finds heterologous vaccine booster evokes robust immunity to SARS-CoV-2 Omicron variant

The current study examines the role of heterologous vaccination, an area that lacks much clarity.

11 Jan 2022

NeoCura and PhoreMost Announce Research Collaboration to Explore Novel Cancer Therapeutics

NeoCura and PhoreMost today announced an oncology drug discovery research collaboration.

From PhoreMost 11 Jan 2022

Latest tools for COVID-19 Omicron variant research

AMSBIO has announced new additions to its portfolio of tools for COVID-19 research - two monoclonal antibodies that recognize the Spike RBD (B.1.1.529, Omicron Variant) protein and neutralizes its interaction with ACE2.

From AMS Biotechnology 11 Jan 2022

Immunological factors associated with impaired BNT162b2 mRNA vaccine response in older adults

A new study posted to the pre-print server medRxiv* investigated the significant immune alterations concerning SARS-CoV-2 specific innate and adaptive immunity associated with a lower BNT162b2 mRNA vaccine response in older individuals.

10 Jan 2022

Neurologist receives ERC grant to study novel light-activated drugs with antiepileptic effects

Dr. Michael Wenzel from the Department of Epileptology at the University Hospital Bonn has received a coveted Starting Grant from the European Research Council.

10 Jan 2022

A study on COVID vaccinated vs. unvaccinated that required hospitalization

Researchers compared the characteristics of fully vaccinated and boosted and unvaccinated patients requiring hospitalization for COVID-19.

10 Jan 2022

Biosimilars could drive down drug prices and lead to $38.4 billion savings

Biosimilar drugs could drive down prices for expensive medicines used to treat illnesses such as cancer and rheumatoid arthritis, with savings estimated to be $38.4 billion or 5.9% of projected total U.S. spending on biologics from 2021 to 2025, according to a new RAND Corporation study.

10 Jan 2022

Researchers develop new biopsy technology for profiling multiple tumor microenvironment biomarkers

A team led by University of California, Irvine researchers has developed a new biopsy technology that can profile multiple tumor microenvironment biomarkers simultaneously, revealing cellular spatial organization and interactions that will help advance personalized disease diagnosis and treatment.

10 Jan 2022

JPND announces call for multinational research on understanding the mechanisms of non-pharmacological interventions

The EU Joint Programme - Neurodegenerative Disease Research (JPND) initiative has announced a joint transnational call for multinational research on understanding the mechanisms of non-pharmacological interventions.

10 Jan 2022

SARS-CoV-2 viral mutations shown to have a limited effect on T cell immunity

New research suggests that viral mutations have a minimal effect on T cell immunity, which could explain the protection provided by vaccination against severe COVID-19, despite the significant loss of neutralizing antibodies.

10 Jan 2022

Efficacy of surgical masks and N95 respirators in lowering SARS-CoV-2 transmission

In a new study, researchers determined the adherence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant to masks and respirators and the role of buccal protection in controlling SARS-CoV-2 transmission.

10 Jan 2022

Mathematical modeling the vaccination of children against SARS-CoV-2

Researchers evaluated the safety of mRNA vaccination against SARS-CoV-2 in children using mathematical modeling.

10 Jan 2022

Rapid antigen tests exhibit high accuracy for COVID-19 screening in children

In a new study, researchers evaluated the sensitivity, specificity, and positive predictive values (PPV) and negative predictive values (NPV) of the Abbott BinaxNOW rapid antigen test against the RT-PCR test in pediatric participants below 18 years in the US with high COVID-19 testing from May 7, 2021, to December 6, 2021.

10 Jan 2022

Efficacy News and Research

MAPK4 may play a key role in triple-negative breast cancer

An egg-derived SARS-CoV-2 vaccine and treatment for COVID-19 disease

Engineering higher affinity SARS-CoV-2 antibodies

Study opens up prospects for using virotherapy to treat central nervous system tumors

Third dose of mRNA COVID vaccine induces strong immunity in older adults

Phase 1 clinical trial shows the safety, feasibility of CAR-M cell therapy for solid tumors

Withdrawing steroid treatment found to boost SARS-CoV-2 vaccine-induced immunity in kidney transplant recipients

Study finds heterologous vaccine booster evokes robust immunity to SARS-CoV-2 Omicron variant

NeoCura and PhoreMost Announce Research Collaboration to Explore Novel Cancer Therapeutics

Latest tools for COVID-19 Omicron variant research

Immunological factors associated with impaired BNT162b2 mRNA vaccine response in older adults

Neurologist receives ERC grant to study novel light-activated drugs with antiepileptic effects

A study on COVID vaccinated vs. unvaccinated that required hospitalization

Biosimilars could drive down drug prices and lead to $38.4 billion savings

Researchers develop new biopsy technology for profiling multiple tumor microenvironment biomarkers

JPND announces call for multinational research on understanding the mechanisms of non-pharmacological interventions

SARS-CoV-2 viral mutations shown to have a limited effect on T cell immunity

Efficacy of surgical masks and N95 respirators in lowering SARS-CoV-2 transmission

Mathematical modeling the vaccination of children against SARS-CoV-2

Rapid antigen tests exhibit high accuracy for COVID-19 screening in children

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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