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FDA approves novel device to treat symptoms associated with advanced heart failure

The U.S. Food and Drug Administration today approved the Barostim Neo System for the improvement of symptoms in patients with advanced heart failure who are not suited for treatment with other heart failure devices, such as cardiac resynchronization therapy.

18 Aug 2019

Targeted pancreatic cancer drug shows promise in clinical trials

Researchers have conducted clinical trials with a new drug targeting pancreatic cancer and the initial results are promising.

16 Aug 2019

Removal of a critical enzyme may help cases of sepsis finds research

Scientists at the University of California San Diego School of Medicine have shown that removal of an enzyme called the PH domain Leucine-rich repeat Protein Phosphatase 1 (PHLPP1) could help laboratory mice with sepsis in a model they had created for their experiment. The study titled, “PHLPP1 counter-regulates STAT1-mediated inflammatory signalling,” was published this week in the journal eLife.

15 Aug 2019

New drug to treat pancreatic cancer shows promising results in clinical trial

A clinical trial testing a new drug in pancreatic cancer had promising initial results, report researchers from the University of Michigan Rogel Cancer Center.

14 Aug 2019

Removing single enzyme improves outcomes in mouse model of sepsis

Sepsis occurs when the body goes overboard in its attempt to fight off an infection. Immune cells rush in, overreact and wreak havoc on tissues and organs, often resulting in organ failure and death.

14 Aug 2019

New research suggests another possible mechanism for Alzheimer’s

Neurofibrillary plaques and tau protein are among the most widely known pathological entities characterizing Alzheimer’s disease (AD), but new research at the University of California, Riverside, has come up with another plausible explanation for this debilitating disorder.

13 Aug 2019

Bioinspired method detects and detoxifies harmful chemicals in single step

Many industrial and agriculture processes use chemicals that can be harmful for workers and the ecosystems where they accumulate.

12 Aug 2019

Researchers test new drug to treat patients with chylomicronemia syndrome

People with familial chylomicronemia syndrome are born with a genetic mutation that means they can't produce an enzyme called lipoprotein lipase.

9 Aug 2019

Treatment with both targeted cancer therapy and MS drug halts glioblastoma stem cells

Glioblastoma is an aggressive form of brain cancer that infiltrates surrounding brain tissue, making it extremely difficult to treat with surgery.

9 Aug 2019

New drug combination successfully reduces levels of bovine leukemia virus

Scientists have succeeded in reducing levels of the bovine leukemia virus in cows with severe infections by combining an immune checkpoint inhibitor and an enzyme inhibitor.

2 Aug 2019

Researchers reveal undiscovered hot spots on surface of bacteria's critical enzyme

Researchers reveal previously undiscovered hot spots on the surface of bacteria's critical enzyme, which could guide novel approaches to antibiotic design.

2 Aug 2019

New antibiotics on the horizon as scientists discover a weakness in the cell wall of pathogenic bacteria

Researchers have discovered a weak spot in the cell wall of pathogenic bacteria that could lead to the development of new antibiotics.

1 Aug 2019

Scientists redesign chemotaxis by creating artificial nanoswimmers from gold nanoparticles

Bacteria can actively move towards a nutrient source—a phenomenon known as chemotaxis—and they can move collectively in a process known as swarming.

1 Aug 2019

Simple, accurate, and fast: the new "sniff-cam" disease detector

It’s not just about garlic on the breath any more; your breath could now help reveal a variety of diseases. The science behind it is that the human body excretes a number of volatile compounds through the breath, and the type and proportion of these vary with the kind of disease.

1 Aug 2019

Glowing cholesterol helps researchers to fight cardiovascular disease

A newly developed technique that shows artery clogging fat-and-protein complexes in live fish gave investigators from Carnegie, Johns Hopkins University, and the Mayo Clinic a glimpse of how to study heart disease in action.

31 Jul 2019

Highly sensitive 'sniff-cam' to detect disease biomarkers

Having bad breath can mean someone ate a smelly lunch, but it could indicate that the person is sick. Various scent compounds have been linked to illnesses such as diabetes, lung cancer and Parkinson's disease, leading scientists to develop technology that measures these substances.

31 Jul 2019

Study reveals the complexities of viral evolution

Comparing a living cell to a virus is a bit like comparing the Sistine Chapel to a backyard dog house. Lacking the intricate machinery of living cells, viruses represent biology stripped down to an extreme level. They are the true minimalists of the biological world.

31 Jul 2019

Understanding creation of antibiotic scaffolds could drive new class of antibiotics

Understanding how antibiotic scaffolds are constructed in nature can help scientists prospect for new classes of antibiotics through DNA sequencing and genome mining.

31 Jul 2019

Study discovers paradoxical proinflammatory effect of endocannabinoids in the brain

A new study led by the Neuropharmacology Laboratory -NeuroPhar at UPF shows that increasing endocannabinoids in the brain may cause inflammation in specific brain areas such as the cerebellum, which is associated with problems of fine motor coordination.

30 Jul 2019

FDA clears existing tests with new indications to aid in the diagnosis of Lyme disease

Today, the U.S. Food and Drug Administration cleared for marketing four previously cleared tests with new indications to aid in the diagnosis of Lyme disease.

30 Jul 2019

Enzyme News and Research

FDA approves novel device to treat symptoms associated with advanced heart failure

Targeted pancreatic cancer drug shows promise in clinical trials

Removal of a critical enzyme may help cases of sepsis finds research

New drug to treat pancreatic cancer shows promising results in clinical trial

Removing single enzyme improves outcomes in mouse model of sepsis

New research suggests another possible mechanism for Alzheimer’s

Bioinspired method detects and detoxifies harmful chemicals in single step

Researchers test new drug to treat patients with chylomicronemia syndrome

Treatment with both targeted cancer therapy and MS drug halts glioblastoma stem cells

New drug combination successfully reduces levels of bovine leukemia virus

Researchers reveal undiscovered hot spots on surface of bacteria's critical enzyme

New antibiotics on the horizon as scientists discover a weakness in the cell wall of pathogenic bacteria

Scientists redesign chemotaxis by creating artificial nanoswimmers from gold nanoparticles

Simple, accurate, and fast: the new "sniff-cam" disease detector

Glowing cholesterol helps researchers to fight cardiovascular disease

Highly sensitive 'sniff-cam' to detect disease biomarkers

Study reveals the complexities of viral evolution

Understanding creation of antibiotic scaffolds could drive new class of antibiotics

Study discovers paradoxical proinflammatory effect of endocannabinoids in the brain

FDA clears existing tests with new indications to aid in the diagnosis of Lyme disease

Biochemical Assays for Efficient Hit Prioritization After Screening eBook

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