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Research shows how obesity sets the stage for diabetes

Obesity is probably the most important factor in the development of insulin resistance, but science's understanding of the chain of events is still spotty. Now, researchers at the Salk Institute for Biological Studies have filled in the gap and identified the missing link between the two.

22 Jun 2009

Goby fish may bring new drugs for high blood pressure

Medical scientists at the University of Leicester are investigating how a species of fish from the Pacific Ocean could help provide answers to tackling chronic conditions such as hereditary high blood pressure and kidney disease.

22 Jun 2009

Women warned not to wait too long to have a baby

Women are being warned that they should consider starting a family before the age of 35 or they will risk missing out on motherhood.

21 Jun 2009

HIV antibody tests unreliable for early infections in teens

A previously healthy teenager shows up at the doctor's office with a sore throat, fever, aches and general malaise. Routine blood tests are normal, an HIV test comes back negative, and the pediatrician sends the patient home with a diagnosis of acute viral infection.

21 Jun 2009

Omega-3 fatty acids may protect against progression of age-related macular degeneration

Omega-3 fatty acids found in fatty fish such as tuna and salmon may protect against progression of age-related macular degeneration (AMD), but the benefits appear to depend on the stage of disease and whether certain supplements are taken, report researchers at the Laboratory for Nutrition and Vision Research (LNVR), Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University.

18 Jun 2009

Young adults with poor fitness levels on road to diabetes in middle age

Most healthy 25 year olds don't stay up at night worrying whether they are going to develop diabetes in middle age. The disease is not on their radar, and middle age is a lifetime away.

18 Jun 2009

Targeting tumor behavior may find new anti-cancer agents

Ohio State University cancer researchers have used computational and genomic methods to identify possible anti-cancer agents that may block a particular kind of tumor behavior. The agents target multiple genes associated with that behavior at one time.

18 Jun 2009

Scientists edit genes in human stem cells

Researchers at the Johns Hopkins School of Medicine have successfully edited the genome of human- induced pluripotent stem cells, making possible the future development of patient-specific stem cell therapies. Reporting this week in Cell Stem Cell, the team altered a gene responsible for causing the rare blood disease paroxysmal nocturnal hemoglobinuria, or PNH, establishing for the first time a useful system to learn more about the disease.

18 Jun 2009

Obesity may reduce brain gray matter in postmenopausal women

Results from a small study of postmenopausal women suggest that obesity might relate to a reduced volume of gray matter in the brain. However, whether the results have relevance in a woman's day-to-day life is unclear.

18 Jun 2009

Gout gene discovered

Having partnered last year with an international team that surveyed the genomes of 12,000 individuals to find a genetic cause for gout, Johns Hopkins scientists now have shown that the malfunctioning gene they helped uncover can lead to high concentrations of blood urate that forms crystals in joint tissue, causing inflammation and pain - the hallmark of this disease.

18 Jun 2009

Research uncovers clues to the development of cancers in AIDS patients

In a series of recently-published articles, a research team from the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center has uncovered clues to the development of cancers in AIDS patients.

17 Jun 2009

“Life force” linked to body’s ability to withstand stress

Our ability to withstand stress-related, inflammatory diseases may be associated, not just with our race and sex, but with our personality as well, according to a study published in the July issue of the journal Brain, Behavior and Immunity. Especially in aging women, low levels of the personality trait extraversion may indicate that blood levels of a key inflammatory molecule have crossed over a threshold linked to a doubling of risk of death within five years.

17 Jun 2009

New diagnostic technique detects possible Alzheimer's biomarker in blood

A new diagnostic technique which may greatly simplify the detection of Alzheimer's disease has been discovered by researchers at McGill University and the affiliated Lady Davis Institute for Medical Research at Montreal's Jewish General Hospital (JGH).

17 Jun 2009

Novel light-sensitive compounds show promise for photodynamic cancer therapy

Chemists at the University of California, Santa Cruz, have developed novel compounds that show promise for photodynamic cancer therapy, which uses light-activated drugs to kill tumor cells.

17 Jun 2009

New understanding on how "trans fats" gum up cellular machinery

Partially hydrogenated vegetable oils in processed foods contain trans fatty acids that interfere with the regulation of blood flow. A new report reveals a new way in which these "trans fats" gum up the cellular machinery that keeps blood moving through arteries and veins.

17 Jun 2009

Minimally invasive treatment of brain tumors on the horizon

Duke University engineers have taken a first step toward a minimally invasive treatment of brain tumors by combining chemotherapy with heat administered from the end of a catheter.

17 Jun 2009

Six 'major health agencies' form alliance to address chronic diseases in developing countries

A group of "major health agencies" from Australia, Canada, China, the U.K. and the U.S., which "together control 80 percent of the world's public health-research funding," have joined together to form the Global Alliance for Chronic Diseases (GACD) to combat chronic diseases in developing countries, Time reports (Walsh, Time, 6/16).

17 Jun 2009

Opinion: U.S. should double global maternal, child health spending; Ban, Chan want 'global solidarity'; resources for diabetes, HIV/AIDS

Although "child survival is improving - albeit way too slowly - in most regions of the world," sub-Saharan Africa "continues to have the world's highest child-mortality rates," former U.S. Senate Majority Leader Bill Frist, who serves as the chairman of Save the Children's Survive to 5 campaign, writes in a Washington Times opinion piece. Frist asserts, "We cannot continue to allow one of every seven African children to die when it is so readily within our reach to prevent those deaths."

17 Jun 2009

Simple blood test detects molecular marker of aging in humans

In 2004, researchers at the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center announced a crucial discovery in the understanding of cellular aging. They found that as cells and tissues age, the expression of a key protein, called p16INK4a, dramatically increases in most mammalian organs. Because p16INK4a is a tumor suppressor protein, cancer researchers are interested in its role in cellular aging and cancer prevention.

17 Jun 2009

Trial of new ‘combo’ treatment for hepatitis C

In a multi-center trial led by a Saint Louis University researcher, investigators found that a new combination therapy of daily consensus interferon and ribavirin helps some hepatitis C patients who have not responded to previous treatment.

17 Jun 2009