Research News and Research

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Rescheduling drugs can reduce use as well as the dangers, study finds

Many nations place drugs into various schedules or categories according to their risk of being abused and their medical value.

3 Feb 2021

New drug cocktail offers hope to patients with highly drug-resistant tuberculosis

A new three-drug, all-oral, six-month treatment is providing hope to patients in Tajikistan with highly drug-resistant forms of tuberculosis, which until now had limited treatment options and poor prognosis.

3 Feb 2021

Exploring the living quality in high-density housing

When we build new apartment block developments, we have to weigh up a number of factors, such as the number of apartments, their layouts, and access to light and a view.

3 Feb 2021

Spark Therapeutics launches gene therapy clinical trial for late-onset Pompe disease

Pompe disease is a hereditary genetic disorder caused by a deficiency of acid alpha-glucosidase leading to build-up of glycogen in the lyosomes, which then causes cell damage in various tissues, in particular the heart, the muscles, the liver and the nervous system.

3 Feb 2021

Study reveals a deep digital health divide within the older population

The COVID-19 pandemic is a great example of the importance of access to the Internet and to digital health information.

3 Feb 2021

Scientists unravel the workings of a mysterious protein implicated in movement disorders

Scientists at Scripps Research have clarified the workings of a mysterious protein called Gαo, which is one of the most abundant proteins in the brain and, when mutated, causes severe movement disorders.

3 Feb 2021

Preclinical study uncovers how Zika virus passes from mother to fetus during pregnancy

A preclinical study by a University of South Florida Health Morsani College of Medicine research team has discovered a new mechanism for how Zika virus can pass from mothers to their children during pregnancy - a process known as vertical transmission.

3 Feb 2021

Study gives new clues to how muscle wasting occurs on a cellular level

Muscle wasting, or the loss of muscle tissue, is a common problem for people with cancer, but the precise mechanisms have long eluded doctors and scientists. Now, a new study led by Penn State researchers gives new clues to how muscle wasting happens on a cellular level.

3 Feb 2021

Clinical trials of new treatments for COVID-19 often do not include vulnerable populations

Studies examining the effectiveness of treatments for COVID-19 often do not include the very populations hardest hit by the disease, according to a new review by University of Chicago Medicine researchers.

3 Feb 2021

Early use of therapeutic anticoagulation does not improve survival of critically ill COVID-19 patients

Although abnormal blood clotting has been identified as one of the primary causes of death from COVID-19, early treatment in an intensive care unit (ICU) with therapeutic anticoagulation (anti-clotting) for adults who are critically ill with COVID-19 does not appear to improve chances of survival, and could do more harm than good by increasing the risk for major bleeding, a multicenter research group cautions.

3 Feb 2021

Phase 1 clinical trial of novel HIV vaccine approach shows promising results

A phase 1 clinical trial testing a novel vaccine approach to prevent HIV has produced promising results, IAVI and Scripps Research announced today.

3 Feb 2021

Latest clinical trial supports UK’s decision to delay second COVID vaccine dose

Researchers in the UK, South Africa and Brazil have reported the latest efficacy results from phase III trials of the Oxford–AstraZeneca vaccine currently being rolled out in the UK to protect against coronavirus disease 2019 (COVID-19).

3 Feb 2021

Dispelling vaccine misinformation and myths in California’s breadbasket

Dust swirled in the air as Luz Gallegos parked her SUV on the side of a dirt road. She had just learned that her aunt died of covid-19 — the third family member to succumb to the disease in only two weeks.

3 Feb 2021

Research could open the door to next-generation of cancer drugs that work better

Some of the most commonly used drugs for treating hereditary breast and ovarian cancers may not work the way we thought they did, according to new University of Colorado Boulder research.

3 Feb 2021

Biomarkers could help discriminate cancer therapy-associated kidney injury from other causes

A study by Mayo Clinic researchers published in Kidney International Reports finds that immune checkpoint inhibitors, may have negative consequences in some patients, including acute kidney inflammation, known as interstitial nephritis. Immune checkpoint inhibitors are used to treat cancer by stimulating the immune system to attack cancerous cells.

3 Feb 2021

Experimental intranasal influenza vaccine produces durable immune response

An experimental single-dose, intranasal influenza vaccine was safe and produced a durable immune response when tested in a Phase 1 study published in the Journal of Clinical Investigation.

3 Feb 2021

Scientists receive award to explore how diet and metabolism influence the immune system

A pair of scientists from Van Andel Institute and the National Institute of Allergy and Infectious Diseases have been granted a three-year, $1.5 million Allen Distinguished Investigator award from The Paul G. Allen Frontiers Group, a division of the Allen Institute, to better understand how diet and metabolism influence the immune system's ability to fight off threats such as infections.

3 Feb 2021

Major changes in life influence the amount of physical activity

Life changes influence the amount of physical activity in a person, according to a recent study by the University of Jyväskylä.

3 Feb 2021

Moffitt researchers reveal why some ovarian cancer patients evolve better than others

The prognosis of ovarian cancer is poor, with an estimated five-year survival of only 40% for advanced disease, the stage at which most ovarian carcinomas are diagnosed.

3 Feb 2021

CU researchers awarded NEI's 3D ROC prize to accelerate development of new therapies

Natalia Vergara, PhD, assistant professor of ophthalmology at the University of Colorado School of Medicine, has been awarded a 3D ROC prize by the National Eye Institute for her research team's work to create better models to accelerate the development of new therapies for retinal diseases.

3 Feb 2021

Research News and Research

Rescheduling drugs can reduce use as well as the dangers, study finds

New drug cocktail offers hope to patients with highly drug-resistant tuberculosis

Exploring the living quality in high-density housing

Spark Therapeutics launches gene therapy clinical trial for late-onset Pompe disease

Study reveals a deep digital health divide within the older population

Scientists unravel the workings of a mysterious protein implicated in movement disorders

Preclinical study uncovers how Zika virus passes from mother to fetus during pregnancy

Study gives new clues to how muscle wasting occurs on a cellular level

Clinical trials of new treatments for COVID-19 often do not include vulnerable populations

Early use of therapeutic anticoagulation does not improve survival of critically ill COVID-19 patients

Phase 1 clinical trial of novel HIV vaccine approach shows promising results

Latest clinical trial supports UK’s decision to delay second COVID vaccine dose

Dispelling vaccine misinformation and myths in California’s breadbasket

Research could open the door to next-generation of cancer drugs that work better

Biomarkers could help discriminate cancer therapy-associated kidney injury from other causes

Experimental intranasal influenza vaccine produces durable immune response

Scientists receive award to explore how diet and metabolism influence the immune system

Major changes in life influence the amount of physical activity

Moffitt researchers reveal why some ovarian cancer patients evolve better than others

CU researchers awarded NEI's 3D ROC prize to accelerate development of new therapies

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